Development Level

Tbio 21 | 11,445
Tchem 8 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 3 | 298
preweaning lethality, complete... 3 | 979
decreased leukocyte cell numbe... 2 | 73
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased heart weight 2 | 62
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased anxiety-related resp... 1 | 2
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
thin ventricular wall 1 | 24

Disease

Carcinoma 30 | 11,493
psoriasis 22 | 6,694
medulloblastoma, large-cell 21 | 6,241
ovarian cancer 20 | 8,520
glioblastoma 19 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
group 3 medulloblastoma 17 | 4,104
adult high grade glioma 16 | 3,801
lung cancer 16 | 4,740
primitive neuroectodermal tumor 15 | 3,035
Autosomal recessive predisposition 14 | 1,442
astrocytic glioma 14 | 2,597
osteosarcoma 14 | 7,950
Astrocytoma, Pilocytic 13 | 3,081
ependymoma 13 | 4,679
Epilepsy 12 | 792
Seizures 12 | 596
oligodendroglioma 12 | 2,850
Intellectual disability 11 | 1,016
Pick disease 11 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
lung carcinoma 10 | 2,843
non-small cell lung cancer 10 | 2,890
Breast cancer 9 | 3,578
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Schizophrenia 9 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
subependymal giant cell astrocytoma 9 | 2,287
Muscle hypotonia 8 | 571
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Atopic dermatitis 7 | 952
Liver Cirrhosis, Experimental 7 | 769
adrenocortical carcinoma 7 | 1,428
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
nasopharyngeal carcinoma 7 | 1,058
Down syndrome 6 | 499
Hyperammonemia 6 | 30
diabetes mellitus 6 | 1,728
esophageal adenocarcinoma 6 | 737
Argininosuccinic aciduria 5 | 17
Cancer 5 | 2,499
Infantile onset 5 | 238
Lethargy 5 | 77
Obesity 5 | 678
Succinic semialdehyde dehydrogenase deficiency 5 | 16
active ulcerative colitis 5 | 764
cystic fibrosis 5 | 1,696
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Autistic Disorder 4 | 364
Cerebellar Ataxia 4 | 304
Cerebral Edema 4 | 30
Citrullinemia 4 | 14
Comatose 4 | 56
Failure to gain weight 4 | 365
Hyperreflexia 4 | 209
Kidney cancer 4 | 2,613
Multiple myeloma 4 | 1,332
Pediatric failure to thrive 4 | 365
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
gastric cancer 4 | 459
juvenile dermatomyositis 4 | 1,187
nephrosclerosis 4 | 333
tuberculosis 4 | 2,010
Alcoholic Intoxication, Chronic 3 | 289
Cerebral atrophy 3 | 178
Delayed speech and language development 3 | 112
Depressive disorder 3 | 409
Electroencephalogram abnormal 3 | 101
Heart disease 3 | 306
Kidney disease 3 | 430
Language Delay 3 | 112
Mental Depression 3 | 333
Mood Disorders 3 | 184
Respiratory Insufficiency 3 | 132
Speech Delay 3 | 112
Speech impairment 3 | 112
Vomiting 3 | 116
active Crohn's disease 3 | 922
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
medulloblastoma 3 | 720
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819

Tissue

Digestive Tract 35 | 17,369
Liver and Pancreas 35 | 16,750
Skin and soft tissues 35 | 17,230
Female tissues 34 | 17,400
Nervous System 34 | 16,725
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Endocrine System 33 | 18,159
Male tissues 33 | 17,142
Respiratory system 32 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Enzyme 34 | 4,145
Non-IDG 1 | 12,091

KEGG Pathway

Alanine, aspartate and glutama... 35 | 35
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.33579 2.63 48
Argininosuccinate lyase ASL Tbio Enzyme -2.13476 130.8 199
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 Tbio Enzyme -1.47858 32.0 77
Glutaminase kidney isoform, mitochondrial GLS Tchem Enzyme -2.92171 795.3 268
Alanine aminotransferase 1 GPT Tbio Enzyme -2.47451 285.2 217
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Succinate-semialdehyde dehydrogenase, mitochondrial ALDH5A1 Tclin Enzyme -2.23586 168.4 347
CAD protein CAD Tchem Non-IDG -2.23887 168.4 224