Development Level

Tbio 80 | 11,445
Tchem 32 | 1,598
Tclin 28 | 613
Tdark 7 | 6,588

Collection

Ion Channel: IDG Consortium (T... 15 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal bone structure 7 | 187
increased startle reflex 7 | 112
abnormal behavior 6 | 298
increased heart weight 4 | 62
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
hypoactivity 3 | 132
abnormal locomotor behavior 2 | 24
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased mean corpuscular vol... 2 | 79
decreased mean platelet volume 2 | 25
decreased total body fat amoun... 2 | 207
edema 2 | 59
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
male infertility 2 | 123
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal glucose homeostasis 1 | 4
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
cyanosis 1 | 7
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged gallbladder 1 | 2
hemorrhage 1 | 23
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

Carcinoma 108 | 11,493
glioblastoma 74 | 5,792
osteosarcoma 72 | 7,950
medulloblastoma, large-cell 71 | 6,241
ovarian cancer 70 | 8,520
psoriasis 69 | 6,694
atypical teratoid / rhabdoid tumor 68 | 5,112
adult high grade glioma 61 | 3,801
ependymoma 52 | 4,679
group 3 medulloblastoma 51 | 4,104
Astrocytoma, Pilocytic 47 | 3,081
primitive neuroectodermal tumor 46 | 3,035
Breast cancer 43 | 3,578
lung cancer 43 | 4,740
Kidney cancer 36 | 2,613
oligodendroglioma 35 | 2,850
astrocytic glioma 32 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
invasive ductal carcinoma 32 | 2,951
lung adenocarcinoma 32 | 2,716
lung carcinoma 32 | 2,843
Cancer 31 | 2,499
subependymal giant cell astrocytoma 30 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
Pick disease 28 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
non-small cell lung cancer 28 | 2,890
Schizophrenia 27 | 1,160
colon cancer 26 | 1,478
diabetes mellitus 26 | 1,728
pituitary cancer 26 | 1,972
Bipolar Disorder 25 | 666
Epilepsy 25 | 792
Hypertension 23 | 396
pancreatic cancer 23 | 2,398
group 4 medulloblastoma 22 | 1,855
ulcerative colitis 21 | 1,819
Heart disease 20 | 306
malignant mesothelioma 20 | 3,232
Atrial Fibrillation 19 | 124
Autosomal recessive predisposition 19 | 1,442
ductal carcinoma in situ 19 | 1,745
interstitial cystitis 19 | 2,312
breast carcinoma 17 | 1,638
tuberculosis 17 | 2,010
Depressive disorder 16 | 409
Hypertensive disease 16 | 292
Congestive heart failure 15 | 113
Obesity 15 | 678
acute quadriplegic myopathy 15 | 1,158
Cardiomyopathy 14 | 116
Hypertrophic Cardiomyopathy 14 | 117
Liver cancer 14 | 604
Parkinson's disease 14 | 392
Cardiomyopathies 13 | 110
Cardiomyopathy, Dilated 13 | 83
Heart failure 13 | 162
Mental Depression 13 | 333
Seizures 13 | 596
adrenocortical carcinoma 13 | 1,428
astrocytoma 13 | 1,146
Asthma 12 | 385
Chronic heart failure 12 | 46
Hypertensive disorder 12 | 56
Myocardial Infarction 12 | 151
Skin cancer 12 | 469
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Alzheimer's disease 11 | 658
Atopic dermatitis 11 | 952
Cerebrovascular disease 11 | 238
Dilated cardiomyopathy 11 | 56
Melanoma 11 | 711
juvenile dermatomyositis 11 | 1,187
Adenoma 10 | 167
Intellectual disability 10 | 1,016
Mood Disorders 10 | 184
Multiple myeloma 10 | 1,332
Rheumatoid arthritis 10 | 1,191
Substance Withdrawal Syndrome 10 | 55
Ventricular arrhythmia 10 | 27
Waldenstrons macroglobulinemia 10 | 765
Dull intelligence 9 | 645
Familial isolated dilated cardiomyopathy 9 | 41
LEFT VENTRICULAR NONCOMPACTION 10 9 | 40
LEFT VENTRICULAR NONCOMPACTION 8 9 | 40
Low intelligence 9 | 645
Major Depressive Disorder 9 | 301
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Myocardial Ischemia 9 | 169
Poor school performance 9 | 645
Stomach Neoplasms 9 | 300
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
Cerebellar Ataxia 8 | 304
Duchenne muscular dystrophy 8 | 601
Polycystic ovary syndrome 8 | 360
gastric carcinoma 8 | 807
primary Sjogren syndrome 8 | 735
spina bifida 8 | 1,074

Tissue

Endocrine System 144 | 18,159
Digestive Tract 140 | 17,369
Male tissues 140 | 17,142
Skin and soft tissues 139 | 17,230
Female tissues 138 | 17,400
Nervous System 138 | 16,725
Blood and immune system 135 | 16,909
Liver and Pancreas 135 | 16,750
Urinary Tract 134 | 16,678
Respiratory system 130 | 16,393
Cardiovascular System 128 | 15,192

Target Family

Enzyme 36 | 4,145
Non-IDG 32 | 12,091
Ion Channel 27 | 344
Kinase 19 | 634
Transporter 15 | 473
Transcription Factor 11 | 1,400
GPCR 7 | 408

KEGG Pathway

Adrenergic signaling in cardio... 147 | 147
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform PPP2R5D Tbio Enzyme -0.70843 3.59 261
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114