Development Level

Tbio 31 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 2 | 298
decreased circulating glucose ... 2 | 126
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal male genitalia morpho... 1 | 3
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 41 | 11,493
Colorectal Neoplasms 29 | 243
Kidney cancer 28 | 2,613
osteosarcoma 21 | 7,950
ovarian cancer 20 | 8,520
psoriasis 20 | 6,694
lung cancer 17 | 4,740
Breast cancer 16 | 3,578
lung carcinoma 16 | 2,843
medulloblastoma, large-cell 16 | 6,241
glioblastoma 15 | 5,792
malignant mesothelioma 15 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Autosomal recessive predisposition 14 | 1,442
atypical teratoid / rhabdoid tumor 13 | 5,112
invasive ductal carcinoma 13 | 2,951
Astrocytoma, Pilocytic 12 | 3,081
lung adenocarcinoma 12 | 2,716
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
non-small cell lung cancer 10 | 2,890
Skin cancer 9 | 469
adult high grade glioma 9 | 3,801
ductal carcinoma in situ 9 | 1,745
Cancer 8 | 2,499
Disease Progression 8 | 136
Liver cancer 8 | 604
Rheumatoid arthritis 8 | 1,191
oligodendroglioma 8 | 2,850
Cholestasis 7 | 155
Liver Cirrhosis, Experimental 7 | 769
Melanoma 7 | 711
Pick disease 7 | 1,894
active Crohn's disease 7 | 922
active ulcerative colitis 7 | 764
adrenocortical carcinoma 7 | 1,428
interstitial cystitis 7 | 2,312
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Adverse reaction to drug 6 | 61
Arthritis, Rheumatoid 6 | 174
Drug-Related Side Effects and Adverse Reactions 6 | 62
Hepatomegaly 6 | 285
Tangier disease 6 | 10
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
group 3 medulloblastoma 6 | 4,104
non-small cell lung carcinoma 6 | 317
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Diarrhea 5 | 253
Dubin-Johnson syndrome 5 | 6
Endometriosis 5 | 540
Failure to gain weight 5 | 365
Liver disease 5 | 237
Pediatric failure to thrive 5 | 365
Peripheral Neuropathy 5 | 134
Schizophrenia 5 | 1,160
Sitosterolemia 5 | 9
acute quadriplegic myopathy 5 | 1,158
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
posterior fossa group A ependymoma 5 | 468
primary Sjogren syndrome 5 | 735
primitive neuroectodermal tumor 5 | 3,035
Adrenoleukodystrophy 4 | 29
Atherosclerosis 4 | 291
Biliary cirrhosis 4 | 45
Bilirubin metabolic disorder 4 | 41
Bipolar Disorder 4 | 666
Carcinoma, squamous cell of head and neck 4 | 31
Cardiovascular system disease 4 | 246
Cholelithiasis 4 | 33
Down syndrome 4 | 499
Endometrial cancer 4 | 311
Epilepsy 4 | 792
Icterus 4 | 82
Lipid metabolism disorder 4 | 114
Pseudoxanthoma elasticum 4 | 18
Splenomegaly 4 | 190
Squamous cell carcinoma of the head and neck 4 | 29
aldosterone-producing adenoma 4 | 665
facioscapulohumeral dystrophy 4 | 288
non primary Sjogren syndrome sicca 4 | 891
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
non diabetic and post-ischemic heart failure 3 | 200
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 44 | 18,159
Digestive Tract 43 | 17,369
Female tissues 43 | 17,400
Nervous System 43 | 16,725
Skin and soft tissues 43 | 17,230
Liver and Pancreas 42 | 16,750
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909
Male tissues 41 | 17,142
Respiratory system 38 | 16,393
Cardiovascular System 34 | 15,192

Target Family

Transporter 41 | 473
Non-IDG 2 | 12,091
Ion Channel 1 | 344

KEGG Pathway

ABC transporters 44 | 44
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 10 ABCA10 Tdark Transporter -0.25772 2.27 36
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 Tbio Transporter -0.85002 7.18 96
ATP-binding cassette sub-family A member 13 ABCA13 Tbio Transporter -1.12588 13.9 0
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
ATP-binding cassette sub-family A member 8 ABCA8 Tbio Transporter -0.83170 7.18 88
Canalicular multispecific organic anion transporter 2 ABCC3 Tbio Transporter -2.46032 287.4 214
Multidrug resistance-associated protein 4 ABCC4 Tchem Transporter -2.56001 341.6 352