Development Level

Tbio 13 | 10,625
Tchem 4 | 1,890

IMPC Term

abnormal coping response 1 | 12
abnormal glucose homeostasis 1 | 5
abnormal tail movements 1 | 12
decreased IgM level 1 | 1
decreased body weight 1 | 174
decreased lean body mass 1 | 195
increased bone mineral content 1 | 92
increased circulating choleste... 1 | 53
preweaning lethality, complete... 1 | 633

Disease

ovarian cancer 11 | 8,484
psoriasis 9 | 6,685
glioblastoma 6 | 5,572
osteosarcoma 6 | 7,933
Breast cancer 5 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
Multiple myeloma 4 | 1,327
atypical teratoid / rhabdoid tumor 4 | 4,369
gastric carcinoma 4 | 832
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
medulloblastoma, large-cell 4 | 6,234
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
pituitary cancer 4 | 1,972
Cancer 3 | 2,346
Degenerative polyarthritis 3 | 93
astrocytic glioma 3 | 2,241
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,713
lung cancer 3 | 4,466
malignant mesothelioma 3 | 3,162
non primary Sjogren syndrome sicca 3 | 840
pilocytic astrocytoma 3 | 3,086
primitive neuroectodermal tumor 3 | 3,031
Carcinoma 2 | 2,147
Cholangiocarcinoma 2 | 32
Chondroma 2 | 12
D-2-hydroxyglutaric aciduria 2 | 9
DOID:2627 2 | 14
Enchondromatosis 2 | 4
Hemangioma 2 | 35
Immune system cancer 2 | 38
Inflammatory dermatosis 2 | 38
Interval angle-closure glaucoma 2 | 2
Liver Cirrhosis, Experimental 2 | 108
Liver carcinoma 2 | 217
Maffucci syndrome 2 | 7
Maple syrup urine disease 2 | 25
Myelofibrosis 2 | 11
Obesity 2 | 616
Ollier disease 2 | 15
Papilloma 2 | 27
Polycystic Ovary Syndrome 2 | 332
Precancerous Conditions 2 | 69
Tropical spastic paraparesis 2 | 17
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
chronic lymphosyte leukemia 2 | 232
diabetes mellitus 2 | 1,663
group 3 medulloblastoma 2 | 2,254
interstitial cystitis 2 | 2,299
lung carcinoma 2 | 2,844
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis 2 | 1,557
tuberculosis and treatment for 3 months 2 | 327
ulcerative colitis 2 | 2,087
2-hydroxyglutaric aciduria 1 | 5
Anemia 1 | 252
Anoxia 1 | 33
Cardiomyopathies 1 | 90
Cardiovascular system disease 1 | 194
Drug-Induced Liver Injury 1 | 118
Dysembryoplastic neuroepithelial tumor 1 | 10
Fatty Liver 1 | 48
Fibrillary astrocytoma 1 | 2
Filariasis 1 | 21
Friedreich ataxia 1 | 23
Ganglioglioma 1 | 16
Giant Cell Glioblastoma 1 | 12
Glioma 1 | 65
Heart failure 1 | 80
Hepatitis B 1 | 103
Huntington's disease 1 | 72
Liver disease 1 | 219
Liver diseases 1 | 66
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 257
Parkinson's disease 1 | 364
Peripheral T-cell lymphoma 1 | 24
Polycythemia Vera 1 | 24
Renal Cell Carcinoma 1 | 199
Retinitis pigmentosa 1 | 153
Weight Gain 1 | 87
Zellweger Syndrome 1 | 38
gliosarcoma 1 | 19
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
non-inflammatory breast cancer 1 | 208

Tissue

Blood and immune system 17 | 17,995
Cardiovascular System 17 | 17,958
Digestive Tract 17 | 18,473
Endocrine System 17 | 18,512
Female tissues 17 | 18,647
Liver and Pancreas 17 | 18,136
Male tissues 17 | 17,969
Nervous System 17 | 18,561
Respiratory system 17 | 17,484
Skin and soft tissues 17 | 18,115
Urinary Tract 17 | 18,444

Target Family

Enzyme 17 | 4,146

KEGG Pathway

2-Oxocarboxylic acid metabolis... 17 | 17
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B Tbio Enzyme -1.13428 13.6 146
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.21924 1416.9 422
Alanine aminotransferase 1 GPT Tbio Enzyme -2.42875 265.2 188
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G Tbio Enzyme -0.19018 0.67 161
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A Tbio Enzyme -1.40593 22.4 131
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.17104 145.2 256
Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 Tchem Enzyme -1.78471 67.3 189
Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 Tchem Enzyme -1.76989 61.1 143
Isocitrate dehydrogenase [NADP], mitochondrial IDH2 Tbio Enzyme -2.83742 700.9 270
Aminoacylase-1 ACY1 Tbio Enzyme -1.98809 99.7 257