Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal limb position 1 | 3
abnormal skin morphology 1 | 50
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased vertical activity 1 | 208
improved glucose tolerance 1 | 79
increased total body fat amoun... 1 | 134
prolonged RR interval 1 | 8
thin skin 1 | 2

Disease

ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
Astrocytoma, Pilocytic 5 | 3,081
Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
adult high grade glioma 4 | 3,801
non-small cell lung cancer 4 | 2,890
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Bruck syndrome 2 | 10
Cervical incompetence 2 | 6
Dentinogenesis imperfecta 2 | 25
Kidney cancer 2 | 2,613
Osteogenesis imperfecta 2 | 34
Osteogenesis imperfecta type 2 2 | 8
Osteogenesis imperfecta type III (disorder) 2 | 11
Osteogenesis imperfecta, dominant perinatal lethal 2 | 5
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
osteogenesis imperfecta type 3 2 | 11
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Acquired scoliosis 1 | 281
Acute cystitis 1 | 35
Amyotrophic lateral sclerosis type 8 1 | 10
Blepharophimosis 1 | 70
Blue sclera 1 | 32
Bronchitis 1 | 43
CD40 deficiency 1 | 4
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Carcinoma, squamous cell of head and neck 1 | 31
Cellulitis 1 | 20
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Curvature of spine 1 | 282
Cystinuria 1 | 18
Death in early childhood 1 | 82
Death in infancy 1 | 82
Degenerative polyarthritis 1 | 115
Diffuse Scleroderma 1 | 7
Dubowitz syndrome 1 | 13
Exophthalmos 1 | 112
Fragile X syndrome 1 | 34
Frequent fractures 1 | 53
Generalized osteopenia 1 | 99
Genu varum 1 | 29
Hereditary spastic paraplegia 36 1 | 3
Hip joint varus deformity - observation 1 | 24
Hydronephrosis 1 | 89
Increased fracture rate 1 | 53
Late fontanel closure 1 | 28
Liver Cirrhosis, Experimental 1 | 769
Liver carcinoma 1 | 240
Long philtrum 1 | 137
Lymphadenitis 1 | 15
Micromelia 1 | 58
Myopia 1 | 176
Narrow thorax 1 | 53
Osteoarthritis 1 | 184
Osteogenesis imperfecta type IV (disorder) 1 | 10
Osteopenia 1 | 99
Pectus excavatum 1 | 100
Pharyngitis 1 | 17
Pleural empyema 1 | 12
Pneumonia 1 | 174
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Ptosis 1 | 48
Pyelonephritis 1 | 13
Rhizomelia 1 | 25
Round face 1 | 45
Round, full face 1 | 45
Scarlet fever 1 | 8
Squamous cell carcinoma of the head and neck 1 | 29
Structure of wormian bone 1 | 24
Tonsillitis 1 | 16
Urinary bladder cancer 1 | 36
Varying degree of multiple fractures 1 | 53
Wide anterior fontanel 1 | 44
Wide cranial sutures 1 | 4
colon cancer 1 | 1,478
facioscapulohumeral dystrophy 1 | 288
fibroadenoma 1 | 559
medulloblastoma 1 | 720
osteogenesis imperfecta type 4 1 | 10
posterior fossa group B ependymoma 1 | 416
pulmonary arterial hypertension 1 | 75
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Enzyme 4 | 4,145
Non-IDG 4 | 12,091

Jensen-TM Tissue

p3h3 8 | 8
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.49306 295.2 60
Ubiquitin-protein ligase E3B UBE3B Tbio Enzyme -2.21700 129.2 44
Cartilage-associated protein CRTAP Tbio Non-IDG -1.47844 29.1 199
Endoplasmic reticulum protein SC65 P3H4 Tbio Non-IDG -1.18768 13.4 90
Cyclin-A1 CCNA1 Tbio Non-IDG -2.02564 107.2 314
Prolyl 3-hydroxylase 3 P3H3 Tbio Enzyme -1.97511 85.0 71
Prolyl 3-hydroxylase 1 P3H1 Tbio Enzyme -1.47252 31.3 199
Stathmin-4 STMN4 Tbio Non-IDG -2.06131 113.1 106