Development Level

Tbio 65 | 11,445
Tchem 23 | 1,598
Tclin 6 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 6 | 239
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 3 | 151
enlarged heart 3 | 210
abnormal behavioral response t... 2 | 66
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased bone mineral density 2 | 126
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal lens morphology 1 | 81
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
absent spleen 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased thermal nociceptive ... 1 | 9
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
shortened ST segment 1 | 10
small spleen 1 | 19
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

Carcinoma 64 | 11,493
ovarian cancer 61 | 8,520
psoriasis 60 | 6,694
osteosarcoma 52 | 7,950
Cancer 49 | 2,499
Breast cancer 45 | 3,578
glioblastoma 45 | 5,792
lung cancer 44 | 4,740
medulloblastoma, large-cell 43 | 6,241
group 3 medulloblastoma 42 | 4,104
atypical teratoid / rhabdoid tumor 40 | 5,112
malignant mesothelioma 40 | 3,232
primitive neuroectodermal tumor 36 | 3,035
non-small cell lung cancer 33 | 2,890
lung adenocarcinoma 32 | 2,716
adult high grade glioma 31 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
invasive ductal carcinoma 29 | 2,951
adrenocortical carcinoma 25 | 1,428
Endometriosis 23 | 540
ependymoma 23 | 4,679
Atopic dermatitis 21 | 952
breast carcinoma 21 | 1,638
colon cancer 21 | 1,478
ulcerative colitis 21 | 1,819
Kidney cancer 20 | 2,613
ductal carcinoma in situ 20 | 1,745
astrocytic glioma 18 | 2,597
pancreatic cancer 18 | 2,398
nasopharyngeal carcinoma 16 | 1,058
Intellectual disability 15 | 1,016
oligodendroglioma 15 | 2,850
Rheumatoid arthritis 14 | 1,191
Multiple myeloma 13 | 1,332
Astrocytoma, Pilocytic 12 | 3,081
Pick disease 12 | 1,894
Schizophrenia 12 | 1,160
Short stature 12 | 531
Small head 12 | 374
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
Dull intelligence 11 | 645
Epilepsy 11 | 792
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
diabetes mellitus 11 | 1,728
Autosomal recessive predisposition 10 | 1,442
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
group 4 medulloblastoma 10 | 1,855
Cognitive delay 9 | 608
Glaucoma 9 | 239
Global developmental delay 9 | 608
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Mental and motor retardation 9 | 608
Micrognathism 9 | 275
Waldenstrons macroglobulinemia 9 | 765
Microcephaly 8 | 166
Nijmegen breakage syndrome 8 | 24
Stomach Neoplasms 8 | 300
astrocytoma 8 | 1,146
interstitial cystitis 8 | 2,312
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
Bloom syndrome 7 | 29
Colorectal Neoplasms 7 | 243
Liver cancer 7 | 604
acute quadriplegic myopathy 7 | 1,158
hepatocellular carcinoma 7 | 547
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Alzheimer's disease 6 | 658
Anteverted nostril 6 | 191
Ataxia telangiectasia 6 | 34
Cataract 6 | 297
Cerebrovascular disease 6 | 238
Congenital Epicanthus 6 | 177
Delayed bone age 6 | 136
Male infertility 6 | 206
Penile hypospadias 6 | 106
Prostatic Neoplasms 6 | 495
Renal Cell Carcinoma 6 | 214
Seizures 6 | 596
Sensorineural Hearing Loss (disorder) 6 | 284
Toxic encephalopathy 6 | 141
Xeroderma pigmentosum 6 | 43
dermatomyositis 6 | 966
esophageal adenocarcinoma 6 | 737
posterior fossa group A ependymoma 6 | 468
primary Sjogren syndrome 6 | 735
Bipolar Disorder 5 | 666
Broad flat nasal bridge 5 | 236
Depressed nasal bridge 5 | 195
acute myeloid leukemia 5 | 783
juvenile dermatomyositis 5 | 1,187
progressive supranuclear palsy 5 | 676
tuberculosis 5 | 2,010

Tissue

Endocrine System 97 | 18,159
Female tissues 96 | 17,400
Skin and soft tissues 96 | 17,230
Blood and immune system 95 | 16,909
Digestive Tract 95 | 17,369
Male tissues 94 | 17,142
Nervous System 94 | 16,725
Respiratory system 94 | 16,393
Urinary Tract 94 | 16,678
Liver and Pancreas 93 | 16,750
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 21 | 4,145
Kinase 14 | 634
Transcription Factor 6 | 1,400
Epigenetic 4 | 242

Jensen-TM Tissue

Vegetative cell 98 | 98
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
ATP-dependent zinc metalloprotease YME1L1 YME1L1 Tbio Enzyme -2.42377 268.0 75
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Serine/threonine-protein phosphatase 4 regulatory subunit 3B PPP4R3B Tbio Enzyme -1.46618 28.8 121
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
DNA topoisomerase 3-alpha TOP3A Tbio Enzyme -2.77897 560.7 45
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577