Development Level

Tbio 182 | 11,445
Tchem 66 | 1,598
Tclin 43 | 613
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
decreased vertical activity 7 | 208
enlarged heart 7 | 210
abnormal heart morphology 6 | 162
embryonic lethality prior to t... 6 | 278
increased heart weight 6 | 62
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
abnormal bone structure 5 | 187
abnormal seminal vesicle morph... 5 | 114
decreased total body fat amoun... 5 | 207
hypoactivity 5 | 132
increased startle reflex 5 | 112
abnormal embryo size 4 | 220
abnormal lens morphology 4 | 81
cataract 4 | 92
decreased grip strength 4 | 116
decreased hemoglobin content 4 | 68
decreased mean corpuscular vol... 4 | 79
embryonic lethality prior to o... 4 | 239
improved glucose tolerance 4 | 79
increased blood urea nitrogen ... 4 | 48
increased circulating alkaline... 4 | 122
abnormal urinary bladder morph... 3 | 11
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
embryonic growth retardation 3 | 106
increased circulating HDL chol... 3 | 80
increased circulating creatini... 3 | 38
increased circulating total pr... 3 | 28
increased total body fat amoun... 3 | 134
short tibia 3 | 97
small superior vagus ganglion 3 | 74
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal femur morphology 2 | 14
abnormal kidney morphology 2 | 65
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased heart left ventricle... 2 | 28
decreased large unstained cell... 2 | 11
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased mean platelet volume 2 | 25
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased circulating alanine ... 2 | 13
increased circulating bilirubi... 2 | 16
increased circulating potassiu... 2 | 29
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
male infertility 2 | 123
prolonged ST segment 2 | 36
small kidney 2 | 16
thin ventricular wall 2 | 24
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
cystolithiasis 1 | 3
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased food intake 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased pulmonary respirator... 1 | 5
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 197 | 11,493
Cancer 172 | 2,499
psoriasis 142 | 6,694
Kidney disease 141 | 430
ovarian cancer 135 | 8,520
diabetes mellitus 121 | 1,728
osteosarcoma 113 | 7,950
glioblastoma 107 | 5,792
lung cancer 106 | 4,740
Hypertension 104 | 396
Autosomal recessive predisposition 95 | 1,442
medulloblastoma, large-cell 89 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 81 | 2,955
malignant mesothelioma 81 | 3,232
Liver disease 77 | 237
pancreatic cancer 77 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 76 | 2,989
Obesity 74 | 678
atypical teratoid / rhabdoid tumor 72 | 5,112
ependymoma 70 | 4,679
tuberculosis 70 | 2,010
adult high grade glioma 69 | 3,801
lung carcinoma 68 | 2,843
non-small cell lung cancer 66 | 2,890
Heart disease 65 | 306
lung adenocarcinoma 65 | 2,716
Breast cancer 64 | 3,578
Coronary artery disease 63 | 268
invasive ductal carcinoma 63 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 63 | 1,962
Anemia 62 | 365
Schizophrenia 62 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 62 | 3,291
cystic fibrosis 60 | 1,696
interstitial cystitis 59 | 2,312
ulcerative colitis 59 | 1,819
Cerebrovascular disease 58 | 238
Atherosclerosis 57 | 291
Hypertensive disease 57 | 292
Astrocytoma, Pilocytic 55 | 3,081
group 3 medulloblastoma 55 | 4,104
Prostatic Neoplasms 53 | 495
Kidney cancer 52 | 2,613
Diarrhea 50 | 253
Liver Cirrhosis, Experimental 49 | 769
Arthritis 47 | 290
ductal carcinoma in situ 45 | 1,745
Asthma 44 | 385
Epilepsy 44 | 792
Lung disease 44 | 142
breast carcinoma 44 | 1,638
Rheumatoid arthritis 43 | 1,191
Osteoporosis 42 | 363
subependymal giant cell astrocytoma 42 | 2,287
Seizures 41 | 596
Chemical and Drug Induced Liver Injury 40 | 195
pituitary cancer 40 | 1,972
Depressive disorder 39 | 409
Pancreatitis 37 | 123
colon cancer 37 | 1,478
Kidney Diseases 36 | 114
adrenocortical carcinoma 36 | 1,428
oligodendroglioma 36 | 2,850
Intellectual disability 34 | 1,016
Liver Cirrhosis 34 | 181
cutaneous lupus erythematosus 34 | 1,057
primitive neuroectodermal tumor 34 | 3,035
Bipolar Disorder 33 | 666
astrocytic glioma 33 | 2,597
primary pancreatic ductal adenocarcinoma 33 | 1,109
Acute kidney injury 32 | 70
Cholestasis 32 | 155
Heart failure 32 | 162
Major Depressive Disorder 32 | 301
Dull intelligence 31 | 645
Endometriosis 31 | 540
Hyperglycemia 31 | 137
Liver carcinoma 31 | 240
Low intelligence 31 | 645
Lung Neoplasms 31 | 232
Melanoma 31 | 711
Mental Retardation 31 | 645
Mental deficiency 31 | 645
Poor school performance 31 | 645
nephrosclerosis 31 | 333
Alzheimer's disease 30 | 658
Autistic Disorder 30 | 364
Hypersensitivity reaction type II disease 30 | 253
Vascular disease 30 | 319
Adenoma 29 | 167
Atopic dermatitis 29 | 952
Mental Depression 29 | 333
Alcoholic Intoxication, Chronic 28 | 289
Breast Neoplasms 28 | 445
Calcinosis 28 | 70
Carcinoma, Hepatocellular 28 | 228
Inflammation 28 | 120
Inflammatory bowel disease 28 | 151
Mammary Neoplasms 28 | 425
Myocardial Infarction 28 | 151

Tissue

Digestive Tract 283 | 17,369
Endocrine System 281 | 18,159
Male tissues 280 | 17,142
Urinary Tract 280 | 16,678
Liver and Pancreas 278 | 16,750
Skin and soft tissues 277 | 17,230
Female tissues 275 | 17,400
Blood and immune system 269 | 16,909
Nervous System 261 | 16,725
Respiratory system 254 | 16,393
Cardiovascular System 220 | 15,192

Target Family

Non-IDG 133 | 12,091
Enzyme 118 | 4,145
Transporter 23 | 473
Kinase 6 | 634
Transcription Factor 6 | 1,400
GPCR 4 | 408
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Urine 298 | 298
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.9 150
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.17330 1408.2 293
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Putative glutathione hydrolase 3 proenzyme GGT3P Tdark Enzyme -3.09193 1683.2 0
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131