Development Level

Tbio 178 | 11,445
Tchem 31 | 1,598
Tclin 15 | 613
Tdark 4 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 6 | 278
increased total body fat amoun... 5 | 134
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
embryonic lethality prior to o... 3 | 239
preweaning lethality, incomple... 3 | 499
abnormal epididymis morphology 2 | 42
abnormal femur morphology 2 | 14
abnormal heart morphology 2 | 162
abnormal ovary morphology 2 | 7
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
absent epididymis 2 | 3
decreased body weight 2 | 161
decreased eosinophil cell numb... 2 | 24
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hypoactivity 2 | 132
increased or absent threshold ... 2 | 101
small superior vagus ganglion 2 | 74
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal skin morphology 1 | 50
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 15
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
absent uterus 1 | 1
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small kidney 1 | 16

Disease

Cancer 172 | 2,499
psoriasis 130 | 6,694
Carcinoma 126 | 11,493
diabetes mellitus 116 | 1,728
Arthritis 88 | 290
Hypersensitivity reaction type II disease 78 | 253
Ankylosing spondylitis 74 | 140
osteosarcoma 72 | 7,950
ovarian cancer 72 | 8,520
Behcet's disease 70 | 89
lung cancer 70 | 4,740
Acquired immunodeficiency syndrome 66 | 197
malignant mesothelioma 63 | 3,232
Uveitis 62 | 103
glioblastoma 61 | 5,792
Rheumatoid arthritis 60 | 1,191
Herpes zoster 59 | 68
Juvenile rheumatoid arthritis 59 | 111
Kidney disease 59 | 430
Human immunodeficiency virus infectious disease 55 | 138
Stevens-Johnson syndrome 53 | 92
tuberculosis 52 | 2,010
Psoriatic arthritis 51 | 86
Liver disease 50 | 237
interstitial cystitis 49 | 2,312
Breast cancer 48 | 3,578
dermatomyositis 48 | 966
Anemia 46 | 365
pancreatic cancer 46 | 2,398
Dermatitis 45 | 157
non-small cell lung cancer 45 | 2,890
invasive ductal carcinoma 44 | 2,951
lung carcinoma 44 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
medulloblastoma, large-cell 43 | 6,241
ulcerative colitis 43 | 1,819
ependymoma 42 | 4,679
Schizophrenia 41 | 1,160
Congenital adrenal hyperplasia 40 | 73
Pre-Eclampsia 40 | 68
Synovitis 40 | 78
cystic fibrosis 40 | 1,696
lung adenocarcinoma 40 | 2,716
Astrocytoma, Pilocytic 39 | 3,081
Multiple Sclerosis 39 | 540
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
Hypertension 38 | 396
Breast Neoplasms 37 | 445
Mammary Neoplasms 37 | 425
Nephritis 37 | 51
Takayasu's arteritis 37 | 53
adult high grade glioma 37 | 3,801
atypical teratoid / rhabdoid tumor 37 | 5,112
Behcet's syndrome 36 | 50
drug-induced hepatitis 36 | 44
ductal carcinoma in situ 36 | 1,745
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
pituitary cancer 34 | 1,972
Hepatitis B 32 | 108
Obesity 32 | 678
breast carcinoma 31 | 1,638
Heart disease 29 | 306
Skin disease 29 | 66
subependymal giant cell astrocytoma 29 | 2,287
Prostatic Neoplasms 28 | 495
Liver Cirrhosis, Experimental 27 | 769
group 3 medulloblastoma 27 | 4,104
Endometriosis 26 | 540
Lung disease 26 | 142
Atherosclerosis 25 | 291
Hemochromatosis 25 | 54
Hypertensive disease 25 | 292
Leprosy 25 | 73
Primary immunodeficiency disease 25 | 54
primitive neuroectodermal tumor 25 | 3,035
Alzheimer's disease 24 | 658
Kidney cancer 24 | 2,613
Stomach Neoplasms 24 | 300
Autosomal recessive predisposition 23 | 1,442
Adenoma 22 | 167
Birdshot chorioretinopathy 22 | 23
Coronary artery disease 22 | 268
Hyperglycemia 22 | 137
Infertility 22 | 188
group 4 medulloblastoma 22 | 1,855
Polycystic ovary syndrome 21 | 360
Vascular disease 21 | 319
cutaneous lupus erythematosus 21 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Asthma 20 | 385
Atopic dermatitis 20 | 952
Depressive disorder 20 | 409
Inflammation 20 | 120
Major Depressive Disorder 20 | 301
adrenocortical carcinoma 20 | 1,428
oligodendroglioma 20 | 2,850
primary pancreatic ductal adenocarcinoma 20 | 1,109
astrocytic glioma 19 | 2,597

Tissue

Endocrine System 151 | 18,159
Digestive Tract 149 | 17,369
Female tissues 147 | 17,400
Skin and soft tissues 147 | 17,230
Male tissues 143 | 17,142
Blood and immune system 142 | 16,909
Liver and Pancreas 140 | 16,750
Respiratory system 140 | 16,393
Urinary Tract 135 | 16,678
Nervous System 134 | 16,725
Cardiovascular System 117 | 15,192

Target Family

Non-IDG 166 | 12,091
Enzyme 22 | 4,145
Transcription Factor 21 | 1,400
Transporter 7 | 473
Kinase 6 | 634
Nuclear Receptor 4 | 48
GPCR 2 | 408

Jensen-TM Tissue

Trophoblast 228 | 228
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 7 NLRP7 Tbio Non-IDG -1.63951 0.00000 84
ETS-related transcription factor Elf-5 ELF5 Tbio Transcription Factor -1.72839 58.0 200
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Homeobox protein orthopedia OTP Tbio Transcription Factor -2.26130 187.7 110
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Disintegrin and metalloproteinase domain-containing protein 12 ADAM12 Tchem Enzyme -2.28901 214.1 347
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173