Development Level

Tbio 103 | 10,625
Tchem 53 | 1,890
Tclin 29 | 602
Tdark 5 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 10 | 633
abnormal bone mineralization 6 | 55
abnormal bone structure 5 | 131
abnormal retina morphology 4 | 100
increased heart weight 4 | 37
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
decreased circulating creatini... 3 | 31
decreased fasted circulating g... 3 | 49
decreased lean body mass 3 | 195
decreased monocyte cell number 3 | 28
abnormal cranium morphology 2 | 32
abnormal head morphology 2 | 10
decreased bone mineral content 2 | 157
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating calcium ... 2 | 33
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
increased mean corpuscular hem... 2 | 93
prenatal lethality prior to he... 2 | 64
short tibia 2 | 82
thrombocytosis 2 | 23
abnormal clavicle morphology 1 | 5
abnormal coat/hair pigmentatio... 1 | 54
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lung morphology 1 | 15
abnormal radius morphology 1 | 8
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal thoracic cage shape 1 | 3
abnormal thoracic vertebrae mo... 1 | 16
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 2
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased NK cell number 1 | 16
decreased body length 1 | 108
decreased circulating chloride... 1 | 32
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased effector memory T-he... 1 | 2
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to o... 1 | 148
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased CD8-positive, naive ... 1 | 3
increased Ly6C high monocyte n... 1 | 12
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating glycerol... 1 | 11
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased memory-marker gamma-... 1 | 2
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 35
long tibia 1 | 13
sparse hair 1 | 6
straub tail 1 | 26
tremors 1 | 34

Disease

Cancer 123 | 2,346
psoriasis 93 | 6,685
ovarian cancer 79 | 8,484
osteosarcoma 74 | 7,933
diabetes mellitus 73 | 1,663
Hypothyroidism 70 | 89
glioblastoma 64 | 5,572
Adenoma 63 | 165
lung cancer 63 | 4,466
medulloblastoma, large-cell 59 | 6,234
Kidney disease 56 | 396
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,289
Obesity 50 | 616
Breast cancer 49 | 3,094
Carcinoma 48 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
pilocytic astrocytoma 47 | 3,086
lung carcinoma 46 | 2,844
pancreatic cancer 46 | 2,300
atypical teratoid / rhabdoid tumor 45 | 4,369
malignant mesothelioma 45 | 3,162
non-small cell lung cancer 43 | 2,798
Hypertension 42 | 287
Prostatic Neoplasms 42 | 471
pediatric high grade glioma 42 | 2,712
Heart disease 41 | 279
Hyperthyroidism 41 | 50
lung adenocarcinoma 41 | 2,713
oligodendroglioma 41 | 2,849
invasive ductal carcinoma 39 | 2,950
Liver disease 38 | 219
pituitary cancer 38 | 1,972
interstitial cystitis 36 | 2,299
Mammary Neoplasms 35 | 410
ulcerative colitis 35 | 2,087
Endometriosis 34 | 535
cystic fibrosis 33 | 1,665
Alzheimer's disease 32 | 644
Atherosclerosis 32 | 275
Cerebrovascular disease 32 | 231
Diarrhea 32 | 155
Osteoporosis 32 | 257
primitive neuroectodermal tumor 32 | 3,031
ductal carcinoma in situ 31 | 1,745
Coronary artery disease 30 | 240
Rheumatoid Arthritis 30 | 1,160
astrocytoma 30 | 1,493
breast carcinoma 30 | 1,614
ependymoma 30 | 2,514
tuberculosis 30 | 1,557
Anemia 29 | 252
Lung Neoplasms 29 | 171
adrenocortical carcinoma 28 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,795
Pick disease 27 | 1,893
Hyperglycemia 26 | 120
Hypoglycemia 26 | 81
astrocytic glioma 26 | 2,241
Asthma 25 | 349
Goiter 25 | 27
Hypersensitivity reaction type II disease 25 | 235
Hypertensive disease 25 | 193
primary pancreatic ductal adenocarcinoma 25 | 1,271
subependymal giant cell astrocytoma 25 | 2,287
Acromegaly 24 | 40
Arthritis 24 | 248
Cushing's syndrome 24 | 47
Hyperinsulinism 24 | 63
Inflammatory bowel disease 24 | 142
Metabolic syndrome X 24 | 155
Lung disease 23 | 132
Pituitary adenoma 23 | 35
posterior fossa group A ependymoma 23 | 1,511
Liver carcinoma 22 | 217
Multiple Sclerosis 22 | 498
Pancreatitis 22 | 97
Thyrotoxicosis 22 | 38
medulloblastoma 22 | 1,524
Brain disease 21 | 83
Schizophrenia 21 | 501
colon cancer 21 | 1,475
sonic hedgehog group medulloblastoma 21 | 1,482
Polycystic Ovary Syndrome 20 | 332
acute quadriplegic myopathy 20 | 1,157
Adenocarcinoma 19 | 115
Colonic Neoplasms 19 | 126
Colorectal Neoplasms 19 | 217
Hyperparathyroidism 19 | 43
group 3 medulloblastoma 19 | 2,254
group 4 medulloblastoma 19 | 1,875
non-small cell lung carcinoma 19 | 413
Atopic dermatitis 18 | 944
Neuropathy 18 | 210
Stomach Neoplasms 18 | 282
sarcoidosis 18 | 358
Peripheral Neuropathy 17 | 303
Vascular disease 17 | 281
atypical teratoid/rhabdoid tumor 17 | 1,095
nasopharyngeal carcinoma 17 | 1,056

Tissue

Digestive Tract 186 | 18,473
Endocrine System 186 | 18,512
Female tissues 186 | 18,647
Nervous System 186 | 18,561
Urinary Tract 185 | 18,444
Liver and Pancreas 183 | 18,136
Skin and soft tissues 183 | 18,115
Cardiovascular System 182 | 17,958
Blood and immune system 181 | 17,995
Male tissues 179 | 17,969
Respiratory system 179 | 17,484

Target Family

Non-IDG 100 | 11,971
Enzyme 41 | 4,146
Transcription Factor 13 | 1,400
Kinase 9 | 634
Nuclear Receptor 9 | 48
Transporter 8 | 473
GPCR 5 | 406
Epigenetic 3 | 242
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Thyroid gland 190 | 190
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Monocarboxylate transporter 8 SLC16A2 Tbio Transporter -2.32240 230.6 103
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein Niban FAM129A Tbio Non-IDG -1.03213 12.4 149
Krueppel-like factor 9 KLF9 Tbio Transcription Factor -1.87911 88.8 139
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952