Development Level

Tbio 41 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
corneal opacity 1 | 32
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23
increased body weight 1 | 25
increased heart weight 1 | 62
male infertility 1 | 123
narrow eye opening 1 | 12
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 36 | 11,493
psoriasis 28 | 6,694
non-small cell lung cancer 26 | 2,890
Breast cancer 23 | 3,578
Cancer 21 | 2,499
esophageal adenocarcinoma 20 | 737
ovarian cancer 19 | 8,520
cystic fibrosis 18 | 1,696
interstitial cystitis 15 | 2,312
lung cancer 15 | 4,740
spina bifida 15 | 1,074
osteosarcoma 14 | 7,950
pancreatic cancer 14 | 2,398
Kidney cancer 13 | 2,613
Palmoplantar keratosis 13 | 74
ductal carcinoma in situ 12 | 1,745
malignant mesothelioma 12 | 3,232
nasopharyngeal carcinoma 11 | 1,058
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
Atopic dermatitis 9 | 952
Keratosis 9 | 37
breast carcinoma 9 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Abnormal blistering of the skin 8 | 54
Autosomal recessive predisposition 8 | 1,442
Blister of skin 8 | 54
Breast Neoplasms 8 | 445
Dystrophia unguium 8 | 53
Mammary Neoplasms 8 | 425
Skin bulla 8 | 54
cutaneous lupus erythematosus 8 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
medulloblastoma, large-cell 8 | 6,241
Cell Transformation, Neoplastic 7 | 97
Neoplastic Cell Transformation 7 | 89
Skin cancer 7 | 469
Squamous cell carcinoma 7 | 129
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
lung carcinoma 7 | 2,843
Adenoma 6 | 167
Ameloblastoma 6 | 24
Carcinoma, Squamous Cell 6 | 110
Congenital ichthyosiform erythroderma 6 | 28
Dermatitis 6 | 157
Epidermolytic hyperkeratosis 6 | 14
Hyperhidrosis disorder 6 | 81
Increased sweating 6 | 81
Leukokeratosis 6 | 19
Leukoplakia, Oral 6 | 20
Liver disease 6 | 237
Melanoma 6 | 711
Nail Diseases 6 | 24
Nail abnormality 6 | 22
Onychogryposis 6 | 13
Papilloma 6 | 44
Pemphigus 6 | 23
Skin disease 6 | 66
Sweating 6 | 81
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Arrhythmogenic right ventricular cardiomyopathy 5 | 30
Bullous pemphigoid 5 | 18
Dental caries 5 | 164
Epidermolysis bullosa 5 | 21
Epidermolysis bullosa simplex 5 | 9
Erythema 5 | 58
Esophageal Squamous Cell Carcinoma 5 | 77
Flushing 5 | 60
Hypotrichosis 5 | 47
Ichthyoses 5 | 41
Liver cancer 5 | 604
Nail dysplasia 5 | 52
Pachyonychia congenita 5 | 10
Rotting teeth 5 | 73
Skin Neoplasms 5 | 69
Squamous cell carcinoma of esophagus 5 | 77
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
periodontitis 5 | 293
Adenoid Cystic Carcinoma 4 | 99
Astrocytoma, Pilocytic 4 | 3,081
Carcinoma, Adenoid Cystic 4 | 99
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Dilated cardiomyopathy 4 | 56
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Failure to gain weight 4 | 365
Pediatric failure to thrive 4 | 365
Prostatic Neoplasms 4 | 495
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 45 | 17,369
Skin and soft tissues 45 | 17,230
Female tissues 44 | 17,400
Blood and immune system 43 | 16,909
Endocrine System 41 | 18,159
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Urinary Tract 40 | 16,678
Liver and Pancreas 37 | 16,750
Respiratory system 36 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

Jensen-TM Tissue

Stratified epithelium 45 | 45
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Cadherin-17 CDH17 Tbio Non-IDG -3.38219 2005.5 312
Hornerin HRNR Tbio Non-IDG -1.33117 22.2 69
Plakophilin-1 PKP1 Tbio Non-IDG -1.86062 76.3 103
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.15644 132.3 116
Keratin, type II cytoskeletal 6A KRT6A Tbio Non-IDG -1.89234 80.6 339