Development Level

Tbio 251 | 10,625
Tchem 179 | 1,890
Tclin 89 | 602
Tdark 7 | 7,003

IMPC Term

preweaning lethality, complete... 25 | 633
decreased lean body mass 12 | 195
preweaning lethality, incomple... 12 | 260
abnormal behavior 10 | 226
embryonic lethality prior to t... 10 | 187
decreased grip strength 8 | 123
decreased bone mineral content 7 | 157
embryonic lethality prior to o... 7 | 148
increased lean body mass 7 | 107
abnormal embryo size 6 | 112
decreased body weight 6 | 174
decreased total body fat amoun... 6 | 186
increased circulating alkaline... 6 | 119
decreased circulating alanine ... 5 | 53
hyperactivity 5 | 108
hypoactivity 5 | 89
increased circulating HDL chol... 5 | 63
abnormal gait 4 | 51
decreased circulating alkaline... 4 | 41
decreased circulating choleste... 4 | 85
decreased prepulse inhibition 4 | 52
enlarged heart 4 | 111
improved glucose tolerance 4 | 56
increased circulating chloride... 4 | 43
increased circulating choleste... 4 | 53
increased mean corpuscular hem... 4 | 93
increased or absent threshold ... 4 | 128
limb grasping 4 | 35
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
abnormal coping response 3 | 12
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
abnormal sleep behavior 3 | 63
decreased body length 3 | 108
decreased circulating HDL chol... 3 | 77
decreased circulating LDL chol... 3 | 37
decreased circulating glucose ... 3 | 121
decreased heart weight 3 | 44
decreased mean corpuscular vol... 3 | 50
increased blood urea nitrogen ... 3 | 44
increased body weight 3 | 42
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 24
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased startle reflex 3 | 38
short tibia 3 | 82
straub tail 3 | 26
tremors 3 | 34
abnormal epididymis morphology 2 | 31
abnormal femur morphology 2 | 14
abnormal lens morphology 2 | 73
abnormal limb bud morphology 2 | 15
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 100
abnormal spinal cord morpholog... 2 | 8
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 35
decreased anxiety-related resp... 2 | 12
decreased blood urea nitrogen ... 2 | 31
decreased bone mineral density 2 | 126
decreased circulating aspartat... 2 | 27
decreased circulating calcium ... 2 | 33
decreased circulating creatini... 2 | 31
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased fasted circulating g... 2 | 49
decreased rib number 2 | 59
decreased total retina thickne... 2 | 20
enlarged epididymis 2 | 27
immune system phenotype 2 | 17
impaired glucose tolerance 2 | 52
increased circulating LDL chol... 2 | 15
increased circulating total pr... 2 | 20
increased erythrocyte cell num... 2 | 26
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 91
increased total body fat amoun... 2 | 57
male infertility 2 | 62
persistence of hyaloid vascula... 2 | 22
premature death 2 | 5
abnormal cranium morphology 1 | 32
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased effector memory CD8-... 1 | 24
decreased mean corpuscular hem... 1 | 34
decreased pulmonary respirator... 1 | 4
embryonic growth retardation 1 | 28
female infertility 1 | 34
increased circulating magnesiu... 1 | 10
increased sacral vertebrae num... 1 | 62

Disease

Cancer 297 | 2,346
psoriasis 274 | 6,685
glioblastoma 267 | 5,572
ovarian cancer 260 | 8,484
medulloblastoma, large-cell 246 | 6,234
lung cancer 221 | 4,466
osteosarcoma 221 | 7,933
pilocytic astrocytoma 191 | 3,086
atypical teratoid / rhabdoid tumor 175 | 4,369
oligodendroglioma 171 | 2,849
lung carcinoma 170 | 2,844
diabetes mellitus 158 | 1,663
malignant mesothelioma 153 | 3,162
invasive ductal carcinoma 148 | 2,950
Alzheimer's disease 145 | 644
pediatric high grade glioma 145 | 2,712
lung adenocarcinoma 134 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 132 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 129 | 2,956
subependymal giant cell astrocytoma 125 | 2,287
interstitial cystitis 123 | 2,299
ulcerative colitis 122 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 121 | 2,988
non-small cell lung cancer 121 | 2,798
pancreatic cancer 120 | 2,300
primitive neuroectodermal tumor 120 | 3,031
Breast cancer 117 | 3,094
cystic fibrosis 111 | 1,665
Schizophrenia 109 | 501
pituitary cancer 109 | 1,972
Kidney disease 108 | 396
Carcinoma 107 | 2,147
astrocytoma 103 | 1,493
Toxic encephalopathy 102 | 131
Cerebrovascular disease 101 | 231
ependymoma 101 | 2,514
Vascular disease 99 | 281
tuberculosis 99 | 1,557
Parkinson's disease 98 | 364
Obesity 97 | 616
posterior fossa group A ependymoma 95 | 1,511
Epilepsy 94 | 346
adult high grade glioma 94 | 2,148
colon cancer 90 | 1,475
Neurodegenerative disease 89 | 383
breast carcinoma 89 | 1,614
astrocytic glioma 88 | 2,241
Arthritis 87 | 248
group 4 medulloblastoma 84 | 1,875
Multiple Sclerosis 83 | 498
Asthma 82 | 349
Pick disease 82 | 1,893
Heart disease 81 | 279
Atherosclerosis 80 | 275
Hypertension 80 | 287
ductal carcinoma in situ 79 | 1,745
Rheumatoid Arthritis 76 | 1,160
Lung disease 74 | 132
cutaneous lupus erythematosus 73 | 1,056
group 3 medulloblastoma 72 | 2,254
Dementia 71 | 129
adrenocortical carcinoma 71 | 1,427
Mammary Neoplasms 70 | 410
atypical teratoid/rhabdoid tumor 69 | 1,095
sonic hedgehog group medulloblastoma 68 | 1,482
Autistic Disorder 66 | 320
Down syndrome 66 | 548
primary pancreatic ductal adenocarcinoma 64 | 1,271
Hypersensitivity reaction type II disease 62 | 235
medulloblastoma 62 | 1,524
gastric carcinoma 61 | 832
Brain disease 60 | 83
Neuropathy 60 | 210
Prostatic Neoplasms 60 | 471
acute quadriplegic myopathy 58 | 1,157
Inflammatory bowel disease 57 | 142
posterior fossa group B ependymoma 56 | 1,530
Coronary artery disease 55 | 240
Liver disease 55 | 219
juvenile dermatomyositis 55 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 55 | 1,795
Endometriosis 54 | 535
Inflammation 54 | 109
Intellectual disability 54 | 573
Atopic dermatitis 52 | 944
Bipolar Disorder 52 | 266
Brain Ischemia 51 | 87
Duchenne muscular dystrophy 50 | 602
Amyotrophic Lateral Sclerosis 48 | 431
Hypertensive disease 48 | 193
Seizures 48 | 95
nasopharyngeal carcinoma 48 | 1,056
Liver carcinoma 47 | 217
Pain agnosia 46 | 99
esophageal adenocarcinoma 45 | 737
Reperfusion Injury 44 | 84
Multiple myeloma 43 | 1,327
Hyperalgesia 42 | 71
dermatomyositis 42 | 933
Adenoma 41 | 165

Tissue

Female tissues 519 | 18,647
Nervous System 519 | 18,561
Digestive Tract 518 | 18,473
Endocrine System 518 | 18,512
Urinary Tract 515 | 18,444
Skin and soft tissues 511 | 18,115
Blood and immune system 509 | 17,995
Cardiovascular System 509 | 17,958
Liver and Pancreas 509 | 18,136
Male tissues 506 | 17,969
Respiratory system 500 | 17,484

Target Family

Non-IDG 259 | 11,971
Enzyme 106 | 4,146
Transcription Factor 38 | 1,400
GPCR 33 | 406
Ion Channel 33 | 341
Kinase 27 | 634
Transporter 22 | 473
Epigenetic 4 | 242
Nuclear Receptor 4 | 48

Jensen-TM Tissue

Spinal cord 526 | 526
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715