Development Level

Tbio 301 | 11,651
Tchem 147 | 1,388
Tclin 97 | 612
Tdark 4 | 6,593

Collection

GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 20 | 499
embryonic lethality prior to t... 13 | 278
abnormal behavior 12 | 298
abnormal embryo size 10 | 220
decreased vertical activity 10 | 208
embryonic lethality prior to o... 10 | 239
hyperactivity 10 | 148
increased total body fat amoun... 9 | 134
increased lean body mass 8 | 172
abnormal gait 7 | 69
decreased lean body mass 7 | 135
enlarged heart 7 | 210
increased circulating alkaline... 7 | 122
increased circulating sodium l... 7 | 71
increased startle reflex 7 | 112
abnormal seminal vesicle morph... 6 | 114
decreased bone mineral content 6 | 151
decreased grip strength 6 | 116
decreased total body fat amoun... 6 | 207
embryonic growth retardation 6 | 106
hypoactivity 6 | 132
increased circulating chloride... 6 | 41
increased circulating choleste... 6 | 66
decreased body weight 5 | 161
decreased mean corpuscular vol... 5 | 79
decreased neutrophil cell numb... 5 | 42
increased circulating HDL chol... 5 | 80
increased mean corpuscular vol... 5 | 92
limb grasping 5 | 41
prolonged ST segment 5 | 36
abnormal heart morphology 4 | 162
decreased circulating LDL chol... 4 | 38
decreased circulating alkaline... 4 | 46
decreased circulating serum al... 4 | 82
improved glucose tolerance 4 | 79
increased circulating total pr... 4 | 28
increased circulating triglyce... 4 | 42
increased fasted circulating g... 4 | 76
increased lymphocyte cell numb... 4 | 32
increased neutrophil cell numb... 4 | 46
prolonged QT interval 4 | 38
abnormal behavioral response t... 3 | 66
abnormal retina morphology 3 | 71
decreased basophil cell number 3 | 16
decreased blood urea nitrogen ... 3 | 51
decreased circulating aspartat... 3 | 34
decreased circulating creatini... 3 | 39
decreased fasted circulating g... 3 | 65
decreased prepulse inhibition 3 | 82
increased bone mineral content 3 | 108
increased circulating iron lev... 3 | 30
increased mean corpuscular hem... 3 | 96
short tibia 3 | 97
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal kidney morphology 2 | 65
abnormal lung morphology 2 | 26
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased anxiety-related resp... 2 | 12
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating bilirubi... 2 | 19
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased heart left ventricle... 2 | 28
decreased heart rate variabili... 2 | 13
decreased heart weight 2 | 27
decreased lactate dehydrogenas... 2 | 16
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
edema 2 | 59
enlarged kidney 2 | 14
enlarged uterus 2 | 11
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral density 2 | 72
increased circulating alanine ... 2 | 13
increased circulating magnesiu... 2 | 10
increased circulating serum al... 2 | 22
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
male infertility 2 | 123
premature death 2 | 5
small superior vagus ganglion 2 | 74
thin ventricular wall 2 | 24

Disease

Carcinoma 375 | 11,493
Cancer 317 | 2,499
glioblastoma 289 | 5,792
psoriasis 284 | 6,694
ovarian cancer 276 | 8,520
medulloblastoma, large-cell 256 | 6,241
lung cancer 242 | 4,740
atypical teratoid / rhabdoid tumor 236 | 5,112
osteosarcoma 235 | 7,950
ependymoma 234 | 4,679
Schizophrenia 233 | 1,160
Astrocytoma, Pilocytic 199 | 3,081
adult high grade glioma 196 | 3,801
diabetes mellitus 175 | 1,728
lung carcinoma 175 | 2,843
oligodendroglioma 175 | 2,850
malignant mesothelioma 172 | 3,232
group 3 medulloblastoma 169 | 4,104
Alzheimer's disease 162 | 658
Breast cancer 159 | 3,578
invasive ductal carcinoma 159 | 2,951
Bipolar Disorder 152 | 666
lung adenocarcinoma 138 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 133 | 2,955
subependymal giant cell astrocytoma 133 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 131 | 3,291
Depressive disorder 130 | 409
non-small cell lung cancer 129 | 2,890
Epilepsy 128 | 792
pancreatic cancer 128 | 2,398
interstitial cystitis 127 | 2,312
astrocytic glioma 125 | 2,597
tuberculosis 125 | 2,010
Kidney cancer 124 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 124 | 2,989
primitive neuroectodermal tumor 124 | 3,035
Kidney disease 118 | 430
cystic fibrosis 115 | 1,696
ulcerative colitis 115 | 1,819
Obesity 113 | 678
pituitary cancer 112 | 1,972
Toxic encephalopathy 110 | 141
Vascular disease 109 | 319
Hypertension 107 | 396
Cerebrovascular disease 104 | 238
Mental Depression 103 | 333
Neurodegenerative disease 103 | 414
Parkinson's disease 103 | 392
Major Depressive Disorder 101 | 301
Seizures 101 | 596
breast carcinoma 99 | 1,638
Arthritis 98 | 290
colon cancer 97 | 1,478
Autosomal recessive predisposition 95 | 1,442
Multiple Sclerosis 91 | 540
Asthma 90 | 385
Intellectual disability 89 | 1,016
Atherosclerosis 88 | 291
Heart disease 88 | 306
Pick disease 87 | 1,894
Alcoholic Intoxication, Chronic 86 | 289
Liver Cirrhosis, Experimental 85 | 769
ductal carcinoma in situ 85 | 1,745
Dementia 84 | 175
Rheumatoid arthritis 84 | 1,191
Unipolar Depression 83 | 250
group 4 medulloblastoma 83 | 1,855
Breast Neoplasms 77 | 445
Lung disease 77 | 142
Autistic Disorder 76 | 364
Mammary Neoplasms 76 | 425
adrenocortical carcinoma 76 | 1,428
cutaneous lupus erythematosus 76 | 1,057
astrocytoma 75 | 1,146
Brain disease 73 | 96
Neuropathy 72 | 261
Down syndrome 71 | 499
Hypersensitivity reaction type II disease 71 | 253
Mood Disorders 71 | 184
Prostatic Neoplasms 68 | 495
Hypertensive disease 65 | 292
Melanoma 65 | 711
pancreatic ductal adenocarcinoma liver metastasis 65 | 1,962
Liver disease 64 | 237
acute quadriplegic myopathy 63 | 1,158
Coronary artery disease 62 | 268
Inflammatory bowel disease 62 | 151
Inflammation 60 | 120
primary pancreatic ductal adenocarcinoma 60 | 1,109
Dull intelligence 59 | 645
Low intelligence 59 | 645
Mental Retardation 59 | 645
Mental deficiency 59 | 645
Poor school performance 59 | 645
gastric carcinoma 59 | 807
juvenile dermatomyositis 58 | 1,187
Brain Ischemia 55 | 110
Endometriosis 55 | 540
Cognitive delay 54 | 608
Global developmental delay 54 | 608

Tissue

Endocrine System 531 | 18,159
Nervous System 520 | 16,725
Digestive Tract 517 | 17,369
Skin and soft tissues 515 | 17,230
Female tissues 514 | 17,400
Male tissues 506 | 17,142
Liver and Pancreas 502 | 16,750
Blood and immune system 501 | 16,909
Urinary Tract 498 | 16,678
Respiratory system 482 | 16,393
Cardiovascular System 440 | 15,192

Target Family

Non-IDG 271 | 12,091
Enzyme 106 | 4,145
Transcription Factor 40 | 1,400
GPCR 35 | 408
Ion Channel 35 | 344
Kinase 29 | 634
Transporter 23 | 473
Epigenetic 5 | 242
Nuclear Receptor 5 | 48

Jensen-TM Tissue

Spinal cord 549 | 549
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Gap junction beta-6 protein GJB6 Tbio Non-IDG -2.99235 908.9 170
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Roundabout homolog 1 ROBO1 Tbio Non-IDG -2.15518 129.8 261