Development Level

Tbio 35 | 10,625
Tclin 28 | 602
Tchem 13 | 1,890
Tdark 4 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased grip strength 3 | 123
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
increased startle reflex 2 | 38
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal vibrissa morphology 1 | 17
brachydactyly 1 | 2
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased eosinophil cell numb... 1 | 41
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating serum al... 1 | 25
increased or absent threshold ... 1 | 128
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small epididymis 1 | 3
small heart 1 | 8
small liver 1 | 8

Disease

medulloblastoma, large-cell 40 | 6,234
Epilepsy 39 | 346
glioblastoma 38 | 5,572
psoriasis 34 | 6,685
osteosarcoma 33 | 7,933
atypical teratoid / rhabdoid tumor 31 | 4,369
Cancer 27 | 2,346
ovarian cancer 27 | 8,484
pilocytic astrocytoma 26 | 3,086
primitive neuroectodermal tumor 26 | 3,031
oligodendroglioma 24 | 2,849
diabetes mellitus 23 | 1,663
pediatric high grade glioma 23 | 2,712
Carcinoma 22 | 2,147
Schizophrenia 22 | 501
astrocytic glioma 21 | 2,241
malignant mesothelioma 20 | 3,162
Hypertension 19 | 287
Alzheimer's disease 18 | 644
Pick disease 18 | 1,893
lung cancer 18 | 4,466
ependymoma 17 | 2,514
lung carcinoma 17 | 2,844
subependymal giant cell astrocytoma 17 | 2,287
Migraine 16 | 79
Cerebrovascular disease 15 | 231
Pain agnosia 15 | 99
adult high grade glioma 15 | 2,148
Obesity 14 | 616
Parkinson's disease 14 | 364
posterior fossa group A ependymoma 14 | 1,511
Diarrhea 13 | 155
Heart disease 13 | 279
Multiple Sclerosis 13 | 498
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
medulloblastoma 13 | 1,524
sonic hedgehog group medulloblastoma 13 | 1,482
Alcohol dependence 12 | 107
Autistic Disorder 12 | 320
Neurodegenerative disease 12 | 383
Toxic encephalopathy 12 | 131
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
Bipolar Disorder 11 | 266
Intellectual disability 11 | 573
Kidney disease 11 | 396
colon cancer 11 | 1,475
lung adenocarcinoma 11 | 2,713
Irritable bowel syndrome 10 | 59
Seizures 10 | 95
astrocytoma 10 | 1,493
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 2,087
Amnestic disorder 9 | 37
Cocaine-Related Disorders 9 | 88
Huntington's disease 9 | 72
Major Depressive Disorder 9 | 106
Neuropathy 9 | 210
Pain 9 | 70
Pancreatitis 9 | 97
Rheumatoid Arthritis 9 | 1,160
Tetanus 9 | 66
cystic fibrosis 9 | 1,665
interstitial cystitis 9 | 2,299
invasive ductal carcinoma 9 | 2,950
pancreatic cancer 9 | 2,300
Asthma 8 | 349
Constipation 8 | 43
Coronary artery disease 8 | 240
Eaton-Lambert syndrome 8 | 40
Hyperglycemia 8 | 120
Hypotension 8 | 53
atypical teratoid/rhabdoid tumor 8 | 1,095
group 3 medulloblastoma 8 | 2,254
group 4 medulloblastoma 8 | 1,875
Allergic hypersensitivity disease 7 | 123
Atherosclerosis 7 | 275
Breast cancer 7 | 3,094
Cerebellar Ataxia 7 | 72
Dementia 7 | 129
Dyspepsia 7 | 34
Hypoglycemia 7 | 81
Long QT syndrome 7 | 52
Substance abuse 7 | 55
non-small cell lung cancer 7 | 2,798
posterior fossa group B ependymoma 7 | 1,530
tuberculosis 7 | 1,557
Anemia 6 | 252
Brain disease 6 | 83
Down syndrome 6 | 548
Gastroesophageal reflux disease 6 | 37
Gastroparesis 6 | 20
Hyperalgesia 6 | 71
Lennox-Gastaut syndrome 6 | 34
Local anesthesia 6 | 40
Simple partial seizure 6 | 26
Status Epilepticus 6 | 85
Substance Withdrawal Syndrome 6 | 52
Tonic-clonic epilepsy 6 | 47
non primary Sjogren syndrome sicca 6 | 840

Tissue

Female tissues 80 | 18,647
Endocrine System 79 | 18,512
Nervous System 79 | 18,561
Urinary Tract 79 | 18,444
Digestive Tract 77 | 18,473
Cardiovascular System 76 | 17,958
Liver and Pancreas 76 | 18,136
Skin and soft tissues 76 | 18,115
Blood and immune system 75 | 17,995
Male tissues 74 | 17,969
Respiratory system 72 | 17,484

Target Family

Non-IDG 37 | 11,971
Ion Channel 22 | 341
Enzyme 12 | 4,146
GPCR 7 | 406
Transcription Factor 1 | 1,400
Transporter 1 | 473

Jensen-TM Tissue

Spike 80 | 80
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
N-acylneuraminate cytidylyltransferase CMAS Tbio Enzyme -3.17782 1533.5 76
Potassium voltage-gated channel subfamily C member 1 KCNC1 Tclin Ion Channel -2.42317 260.8 283
Sodium channel protein type 8 subunit alpha SCN8A Tclin Ion Channel -2.43832 279.5 169
Syncytin-1 ERVW-1 Tbio Non-IDG -3.60744 3712.1 143
Somatostatin SST Tchem Non-IDG -4.13259 13272.3 348
Membrane transport protein XK XK Tbio Non-IDG -4.91542 83211.2 112
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.38727 250.6 241