Development Level

Tbio 503 | 11,445
Tchem 165 | 1,598
Tclin 89 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 33 | 979
preweaning lethality, incomple... 31 | 499
decreased vertical activity 19 | 208
enlarged heart 18 | 210
embryonic lethality prior to t... 17 | 278
increased startle reflex 12 | 112
abnormal behavior 10 | 298
abnormal embryo size 10 | 220
increased total body fat amoun... 10 | 134
abnormal heart morphology 9 | 162
embryonic lethality prior to o... 9 | 239
abnormal bone structure 8 | 187
abnormal seminal vesicle morph... 8 | 114
increased heart weight 8 | 62
abnormal skin morphology 7 | 50
decreased bone mineral content 7 | 151
decreased mean corpuscular vol... 7 | 79
decreased total body fat amoun... 7 | 207
increased circulating alkaline... 7 | 122
abnormal coat-hair pigmentatio... 6 | 64
abnormal lens morphology 6 | 81
abnormal retina morphology 6 | 71
decreased body weight 6 | 161
decreased circulating glucose ... 6 | 126
decreased lymphocyte cell numb... 6 | 83
decreased prepulse inhibition 6 | 82
improved glucose tolerance 6 | 79
increased circulating HDL chol... 6 | 80
increased neutrophil cell numb... 6 | 46
male infertility 6 | 123
short tibia 6 | 97
cataract 5 | 92
decreased blood urea nitrogen ... 5 | 51
decreased body length 5 | 101
decreased circulating HDL chol... 5 | 68
decreased circulating insulin ... 5 | 76
decreased circulating serum al... 5 | 82
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
decreased fasted circulating g... 5 | 65
decreased lean body mass 5 | 135
decreased neutrophil cell numb... 5 | 42
embryonic growth retardation 5 | 106
hyperactivity 5 | 148
hypoactivity 5 | 132
increased bone mineral content 5 | 108
increased circulating calcium ... 5 | 34
increased lean body mass 5 | 172
increased monocyte cell number 5 | 63
prenatal lethality prior to he... 5 | 87
small superior vagus ganglion 5 | 74
abnormal femur morphology 4 | 14
abnormal kidney morphology 4 | 65
abnormal lung morphology 4 | 26
abnormal vibrissa morphology 4 | 25
decreased bone mineral density 4 | 126
decreased circulating alkaline... 4 | 46
decreased circulating calcium ... 4 | 36
decreased eosinophil cell numb... 4 | 24
decreased hemoglobin content 4 | 68
edema 4 | 59
enlarged spleen 4 | 41
hydrometra 4 | 53
impaired glucose tolerance 4 | 75
impaired righting response 4 | 26
increased circulating choleste... 4 | 66
increased circulating total pr... 4 | 28
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular vol... 4 | 92
limb grasping 4 | 41
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal humerus morphology 3 | 11
abnormal retinal vasculature m... 3 | 27
abnormal sleep behavior 3 | 70
abnormal spleen morphology 3 | 55
abnormal testis morphology 3 | 43
abnormal tooth morphology 3 | 24
decreased circulating choleste... 3 | 93
decreased circulating creatini... 3 | 39
decreased circulating free fat... 3 | 31
decreased circulating phosphat... 3 | 27
decreased hematocrit 3 | 46
enlarged lymph nodes 3 | 37
increased blood urea nitrogen ... 3 | 48
increased circulating creatini... 3 | 38
increased circulating serum al... 3 | 22
microphthalmia 3 | 26
persistence of hyaloid vascula... 3 | 33
prolonged ST segment 3 | 36
small testis 3 | 58
abnormal cornea morphology 2 | 31
abnormal head morphology 2 | 10
abnormal liver morphology 2 | 17
corneal opacity 2 | 32
increased body weight 2 | 25
increased circulating bilirubi... 2 | 16
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased large unstained cell... 2 | 5

Disease

Cancer 546 | 2,499
Carcinoma 522 | 11,493
psoriasis 440 | 6,694
ovarian cancer 394 | 8,520
lung cancer 331 | 4,740
osteosarcoma 328 | 7,950
glioblastoma 308 | 5,792
Breast cancer 265 | 3,578
diabetes mellitus 251 | 1,728
medulloblastoma, large-cell 240 | 6,241
malignant mesothelioma 232 | 3,232
ependymoma 228 | 4,679
non-small cell lung cancer 227 | 2,890
pancreatic cancer 223 | 2,398
atypical teratoid / rhabdoid tumor 214 | 5,112
lung carcinoma 210 | 2,843
interstitial cystitis 209 | 2,312
invasive ductal carcinoma 205 | 2,951
lung adenocarcinoma 204 | 2,716
tuberculosis 198 | 2,010
Astrocytoma, Pilocytic 197 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 188 | 3,291
adult high grade glioma 186 | 3,801
Kidney disease 185 | 430
intraductal papillary-mucinous adenoma (IPMA) 182 | 2,955
cystic fibrosis 177 | 1,696
ulcerative colitis 177 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 172 | 2,989
Arthritis 155 | 290
breast carcinoma 152 | 1,638
Autosomal recessive predisposition 151 | 1,442
Kidney cancer 150 | 2,613
Asthma 145 | 385
Schizophrenia 142 | 1,160
ductal carcinoma in situ 141 | 1,745
group 3 medulloblastoma 141 | 4,104
cutaneous lupus erythematosus 137 | 1,057
Hypersensitivity reaction type II disease 133 | 253
Multiple Sclerosis 130 | 540
Hypertension 128 | 396
Obesity 128 | 678
Liver disease 126 | 237
pituitary cancer 126 | 1,972
subependymal giant cell astrocytoma 125 | 2,287
Rheumatoid arthritis 122 | 1,191
oligodendroglioma 120 | 2,850
Atopic dermatitis 117 | 952
Anemia 114 | 365
Breast Neoplasms 114 | 445
Vascular disease 114 | 319
Mammary Neoplasms 113 | 425
Heart disease 112 | 306
primitive neuroectodermal tumor 112 | 3,035
Liver Cirrhosis, Experimental 111 | 769
Atherosclerosis 109 | 291
Lung disease 109 | 142
colon cancer 109 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 106 | 1,962
Inflammatory bowel disease 104 | 151
Melanoma 104 | 711
esophageal adenocarcinoma 103 | 737
astrocytic glioma 102 | 2,597
nasopharyngeal carcinoma 102 | 1,058
adrenocortical carcinoma 97 | 1,428
Prostatic Neoplasms 96 | 495
juvenile dermatomyositis 96 | 1,187
Dermatitis 95 | 157
Alzheimer's disease 93 | 658
Cerebrovascular disease 91 | 238
Coronary artery disease 87 | 268
Hypertensive disease 87 | 292
primary pancreatic ductal adenocarcinoma 87 | 1,109
acute quadriplegic myopathy 82 | 1,158
group 4 medulloblastoma 81 | 1,855
gastric carcinoma 80 | 807
Short stature 79 | 531
Bipolar Disorder 76 | 666
Stomach Neoplasms 76 | 300
Allergic hypersensitivity disease 75 | 126
astrocytoma 75 | 1,146
Epilepsy 74 | 792
Intellectual disability 73 | 1,016
Liver carcinoma 73 | 240
Osteoporosis 72 | 363
Carcinoma, Hepatocellular 71 | 228
Depressive disorder 71 | 409
Diarrhea 71 | 253
Seizures 70 | 596
Skin cancer 70 | 469
dermatomyositis 70 | 966
Adenoma 68 | 167
Lung Neoplasms 68 | 232
Multiple myeloma 68 | 1,332
spina bifida 68 | 1,074
periodontitis 67 | 293
Endometriosis 66 | 540
Pick disease 66 | 1,894
Duchenne muscular dystrophy 65 | 601
Human immunodeficiency virus infectious disease 65 | 138
Pneumonia 64 | 174

Tissue

Skin and soft tissues 704 | 17,230
Digestive Tract 700 | 17,369
Endocrine System 700 | 18,159
Blood and immune system 695 | 16,909
Female tissues 693 | 17,400
Male tissues 684 | 17,142
Urinary Tract 680 | 16,678
Liver and Pancreas 673 | 16,750
Respiratory system 657 | 16,393
Nervous System 650 | 16,725
Cardiovascular System 601 | 15,192

Target Family

Non-IDG 473 | 12,091
Enzyme 156 | 4,145
Transcription Factor 47 | 1,400
Kinase 36 | 634
GPCR 19 | 408
Transporter 13 | 473
Ion Channel 8 | 344
Nuclear Receptor 8 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Skin 763 | 763
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309