Development Level

Tbio 443 | 10,625
Tchem 205 | 1,890
Tclin 80 | 602
Tdark 7 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 26 | 633
preweaning lethality, incomple... 18 | 260
embryonic lethality prior to t... 11 | 187
enlarged heart 10 | 111
abnormal bone structure 9 | 131
decreased bone mineral content 9 | 157
decreased lean body mass 9 | 195
abnormal behavior 8 | 226
decreased total body fat amoun... 8 | 186
abnormal coat/hair pigmentatio... 7 | 54
decreased circulating glucose ... 7 | 121
decreased circulating insulin ... 7 | 75
increased circulating HDL chol... 7 | 63
abnormal bone mineralization 6 | 55
improved glucose tolerance 6 | 56
increased circulating alkaline... 6 | 119
increased heart weight 6 | 37
abnormal retina morphology 5 | 100
decreased body length 5 | 108
decreased body weight 5 | 174
decreased mean corpuscular vol... 5 | 50
decreased prepulse inhibition 5 | 52
embryonic lethality prior to o... 5 | 148
abnormal embryo size 4 | 112
abnormal femur morphology 4 | 14
abnormal heart morphology 4 | 51
abnormal lens morphology 4 | 73
abnormal sleep behavior 4 | 63
abnormal tooth morphology 4 | 24
decreased blood urea nitrogen ... 4 | 31
decreased bone mineral density 4 | 126
decreased circulating HDL chol... 4 | 77
decreased circulating calcium ... 4 | 33
decreased circulating triglyce... 4 | 83
decreased fasted circulating g... 4 | 49
decreased grip strength 4 | 123
decreased heart weight 4 | 44
increased body weight 4 | 42
increased circulating choleste... 4 | 53
increased circulating creatini... 4 | 29
increased grip strength 4 | 83
increased mean corpuscular vol... 4 | 91
increased respiratory quotient 4 | 12
limb grasping 4 | 35
abnormal QRS complex 3 | 25
abnormal eye morphology 3 | 38
abnormal humerus morphology 3 | 11
abnormal skin morphology 3 | 23
cataract 3 | 26
decreased circulating alanine ... 3 | 53
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased circulating free fat... 3 | 39
decreased eosinophil cell numb... 3 | 41
decreased erythrocyte cell num... 3 | 43
decreased hemoglobin content 3 | 53
decreased leukocyte cell numbe... 3 | 54
decreased monocyte cell number 3 | 28
enlarged spleen 3 | 26
hypoactivity 3 | 89
impaired righting response 3 | 19
increased circulating calcium ... 3 | 32
increased lean body mass 3 | 107
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
male infertility 3 | 62
narrow eye opening 3 | 15
short tibia 3 | 82
tremors 3 | 34
abnormal cornea morphology 2 | 24
abnormal cranium morphology 2 | 32
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal head morphology 2 | 10
abnormal kidney morphology 2 | 30
abnormal lung morphology 2 | 15
abnormal retinal pigmentation 2 | 61
abnormal rib morphology 2 | 28
abnormal spleen morphology 2 | 36
abnormal testis morphology 2 | 30
abnormal vibrissa morphology 2 | 17
corneal opacity 2 | 25
decreased circulating serum al... 2 | 79
decreased mean corpuscular hem... 2 | 34
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating bilirubi... 2 | 16
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 20
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased hemoglobin content 2 | 45
prenatal lethality prior to he... 2 | 64
small testis 2 | 37
straub tail 2 | 26

Disease

Cancer 530 | 2,346
psoriasis 416 | 6,685
ovarian cancer 374 | 8,484
osteosarcoma 316 | 7,933
lung cancer 309 | 4,466
glioblastoma 285 | 5,572
diabetes mellitus 232 | 1,663
medulloblastoma, large-cell 232 | 6,234
Breast cancer 212 | 3,094
non-small cell lung cancer 212 | 2,798
pancreatic cancer 210 | 2,300
lung carcinoma 205 | 2,844
ulcerative colitis 205 | 2,087
malignant mesothelioma 204 | 3,162
interstitial cystitis 202 | 2,299
invasive ductal carcinoma 199 | 2,950
lung adenocarcinoma 199 | 2,713
pilocytic astrocytoma 189 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 185 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 182 | 2,956
atypical teratoid / rhabdoid tumor 179 | 4,369
Kidney disease 178 | 396
intraductal papillary-mucinous carcinoma (IPMC) 173 | 2,988
cystic fibrosis 169 | 1,665
Carcinoma 148 | 2,147
tuberculosis 147 | 1,557
pediatric high grade glioma 142 | 2,712
Arthritis 140 | 248
ductal carcinoma in situ 140 | 1,745
breast carcinoma 138 | 1,614
Asthma 133 | 349
cutaneous lupus erythematosus 133 | 1,056
Hypersensitivity reaction type II disease 128 | 235
Multiple Sclerosis 123 | 498
oligodendroglioma 123 | 2,849
subependymal giant cell astrocytoma 122 | 2,287
Rheumatoid Arthritis 120 | 1,160
pituitary cancer 120 | 1,972
Liver disease 118 | 219
Obesity 115 | 616
posterior fossa group A ependymoma 115 | 1,511
Atopic dermatitis 111 | 944
primitive neuroectodermal tumor 109 | 3,031
Heart disease 108 | 279
Mammary Neoplasms 107 | 410
Atherosclerosis 106 | 275
primary pancreatic ductal adenocarcinoma 106 | 1,271
Vascular disease 104 | 281
colon cancer 104 | 1,475
Lung disease 103 | 132
esophageal adenocarcinoma 102 | 737
Hypertension 100 | 287
nasopharyngeal carcinoma 100 | 1,056
ependymoma 97 | 2,514
astrocytoma 96 | 1,493
Inflammatory bowel disease 95 | 142
adult high grade glioma 95 | 2,148
Anemia 94 | 252
adrenocortical carcinoma 94 | 1,427
juvenile dermatomyositis 94 | 1,189
Cerebrovascular disease 92 | 231
Prostatic Neoplasms 91 | 471
Alzheimer's disease 88 | 644
pancreatic ductal adenocarcinoma liver metastasis 85 | 1,795
acute quadriplegic myopathy 83 | 1,157
group 4 medulloblastoma 83 | 1,875
Dermatitis 81 | 107
gastric carcinoma 81 | 832
Coronary artery disease 80 | 240
astrocytic glioma 74 | 2,241
Allergic hypersensitivity disease 73 | 123
group 3 medulloblastoma 73 | 2,254
sonic hedgehog group medulloblastoma 71 | 1,482
primary Sjogren syndrome 69 | 789
Duchenne muscular dystrophy 68 | 602
Adenoma 67 | 165
Stomach Neoplasms 67 | 282
dermatomyositis 67 | 933
Multiple myeloma 66 | 1,327
Endometriosis 65 | 535
Liver carcinoma 64 | 217
Pick disease 64 | 1,893
Diarrhea 61 | 155
Lung Neoplasms 61 | 171
Skin disease 61 | 65
periodontitis 60 | 269
spina bifida 60 | 1,064
Ankylosing spondylitis 58 | 138
Human immunodeficiency virus infectious disease 58 | 92
Pneumonia 58 | 133
autosomal dominant Emery-Dreifuss muscular dystrophy 58 | 499
Hypertensive disease 57 | 193
non-small cell lung carcinoma 57 | 413
Inflammation 56 | 109
sarcoidosis 56 | 358
Hepatitis B 55 | 103
medulloblastoma 55 | 1,524
posterior fossa group B ependymoma 55 | 1,530
Hyperglycemia 54 | 120
Melanoma 54 | 261

Tissue

Female tissues 693 | 18,647
Urinary Tract 690 | 18,444
Digestive Tract 689 | 18,473
Endocrine System 689 | 18,512
Nervous System 689 | 18,561
Blood and immune system 687 | 17,995
Liver and Pancreas 682 | 18,136
Skin and soft tissues 680 | 18,115
Cardiovascular System 677 | 17,958
Respiratory system 675 | 17,484
Male tissues 674 | 17,969

Target Family

Non-IDG 455 | 11,971
Enzyme 151 | 4,146
Transcription Factor 44 | 1,400
Kinase 33 | 634
GPCR 18 | 406
Transporter 13 | 473
Ion Channel 8 | 341
Nuclear Receptor 8 | 48
Epigenetic 3 | 242
TF/Epigenetic 2 | 38

Jensen-TM Tissue

Skin 735 | 735
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231