Development Level

Tbio 81 | 11,651
Tchem 24 | 1,388
Tclin 13 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased bone mineral content 5 | 151
male infertility 5 | 123
decreased bone mineral density 4 | 126
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal retina morphology 2 | 71
abnormal snout morphology 2 | 23
abnormal vocalization 2 | 21
corneal opacity 2 | 32
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased heart weight 2 | 62
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
polydactyly 2 | 7
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cataract 1 | 92
decreased IgM level 1 | 1
decreased basophil cell number 1 | 16
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
long tibia 1 | 25
microphthalmia 1 | 26
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
protruding tongue 1 | 3
short tibia 1 | 97
thin ventricular wall 1 | 24
vertebral transformation 1 | 12

Disease

Carcinoma 91 | 11,493
ovarian cancer 70 | 8,520
osteosarcoma 56 | 7,950
psoriasis 51 | 6,694
glioblastoma 44 | 5,792
Cancer 42 | 2,499
lung cancer 38 | 4,740
medulloblastoma, large-cell 37 | 6,241
group 3 medulloblastoma 33 | 4,104
lung adenocarcinoma 32 | 2,716
Breast cancer 30 | 3,578
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 29 | 4,679
invasive ductal carcinoma 29 | 2,951
primitive neuroectodermal tumor 27 | 3,035
lung carcinoma 26 | 2,843
non-small cell lung cancer 26 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
Multiple myeloma 23 | 1,332
adult high grade glioma 23 | 3,801
diabetes mellitus 23 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
malignant mesothelioma 23 | 3,232
tuberculosis 23 | 2,010
ulcerative colitis 23 | 1,819
Astrocytoma, Pilocytic 22 | 3,081
Kidney cancer 22 | 2,613
pancreatic cancer 21 | 2,398
astrocytic glioma 20 | 2,597
breast carcinoma 20 | 1,638
oligodendroglioma 20 | 2,850
ductal carcinoma in situ 18 | 1,745
Autosomal recessive predisposition 17 | 1,442
interstitial cystitis 16 | 2,312
subependymal giant cell astrocytoma 15 | 2,287
Cerebrovascular disease 14 | 238
Epilepsy 14 | 792
astrocytoma 14 | 1,146
colon cancer 14 | 1,478
pediatric high grade glioma 14 | 1,064
pituitary cancer 14 | 1,972
Coronary artery disease 13 | 268
Heart disease 13 | 306
Rheumatoid arthritis 13 | 1,191
Waldenstrons macroglobulinemia 13 | 765
Hypertension 12 | 396
Liver Cirrhosis, Experimental 12 | 769
Neurodegenerative disease 12 | 414
Obesity 12 | 678
Schizophrenia 12 | 1,160
Anemia 11 | 365
Liver disease 11 | 237
Malaria 11 | 160
Toxic encephalopathy 11 | 141
acute quadriplegic myopathy 11 | 1,158
Alcoholic Intoxication, Chronic 10 | 289
Asthma 10 | 385
Kidney disease 10 | 430
Muscle hypotonia 10 | 571
Short stature 10 | 531
cutaneous lupus erythematosus 10 | 1,057
cystic fibrosis 10 | 1,696
non primary Sjogren syndrome sicca 10 | 891
Pick disease 9 | 1,894
Vascular disease 9 | 319
active Crohn's disease 9 | 922
dermatomyositis 9 | 966
esophageal adenocarcinoma 9 | 737
primary pancreatic ductal adenocarcinoma 9 | 1,109
Alcohol dependence 8 | 107
Atopic dermatitis 8 | 952
Bipolar Disorder 8 | 666
Hypertensive disease 8 | 292
Melanoma 8 | 711
Osteoporosis 8 | 363
Seizures 8 | 596
adrenocortical carcinoma 8 | 1,428
fibroadenoma 8 | 559
group 4 medulloblastoma 8 | 1,855
Alzheimer's disease 7 | 658
Atherosclerosis 7 | 291
Carcinoma, Hepatocellular 7 | 228
Crohn's disease 7 | 321
Dementia 7 | 175
Depressive disorder 7 | 409
Intellectual disability 7 | 1,016
Liver carcinoma 7 | 240
active ulcerative colitis 7 | 764
nasopharyngeal carcinoma 7 | 1,058
Arthritis 6 | 290
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
acute myeloid leukemia 6 | 783
aldosterone-producing adenoma 6 | 665
gastric carcinoma 6 | 807
juvenile dermatomyositis 6 | 1,187
spina bifida 6 | 1,074

Tissue

Endocrine System 115 | 18,159
Digestive Tract 113 | 17,369
Female tissues 113 | 17,400
Blood and immune system 112 | 16,909
Liver and Pancreas 112 | 16,750
Skin and soft tissues 112 | 17,230
Male tissues 111 | 17,142
Urinary Tract 110 | 16,678
Respiratory system 109 | 16,393
Nervous System 108 | 16,725
Cardiovascular System 103 | 15,192

Target Family

Enzyme 55 | 4,145
Non-IDG 42 | 12,091
Transcription Factor 8 | 1,400
Transporter 6 | 473
GPCR 4 | 408
Kinase 3 | 634
Ion Channel 1 | 344

Jensen-TM Tissue

Seedling 119 | 119
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyrin domain-containing protein 1 PYDC1 Tbio Non-IDG -2.88567 750.0 115
Zinc finger protein 346 ZNF346 Tbio Non-IDG -2.28393 188.7 213
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
DnaJ homolog subfamily C member 22 DNAJC22 Tbio Non-IDG -1.84897 65.6 70
Desumoylating isopeptidase 2 DESI2 Tbio Enzyme -2.81944 648.8 75
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
HBS1-like protein HBS1L Tbio Non-IDG -2.55785 357.2 263
Nucleolar complex protein 2 homolog NOC2L Tbio Non-IDG -2.54468 350.1 85
Proline dehydrogenase 1, mitochondrial PRODH Tbio Enzyme -2.88785 779.3 222