1. Home
  2. Targets
Target Filters...

Development Level

Tbio 10 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased circulating alkaline... 1 | 46
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
hypoactivity 1 | 132
increased mean platelet volume 1 | 45
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
ependymoma 5 | 4,679
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Myopathy 3 | 185
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Creatine phosphokinase serum increased 2 | 110
Deglutition Disorders 2 | 132
Electromyogram abnormal 2 | 49
Elevated creatine kinase 2 | 110
Epilepsy 2 | 792
Handgrip myotonia 2 | 3
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperkalemic periodic paralysis 2 | 9
Hypokalemic periodic paralysis 2 | 11
Multiple myeloma 2 | 1,332
Myotonia 2 | 10
Myotonia congenita 2 | 8
Phenotypic variability 2 | 150
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 3 months 2 | 179
Abdominal pain, episodic 1 | 9
Angiofibroma 1 | 7
Bartter disease 1 | 13
Bundle-Branch Block 1 | 8
Chromosome 4q21 deletion syndrome 1 | 6
Congenital myasthenic syndrome, acetazolamide-responsive 1 | 5
Dent disease 1 | 18
Epileptic drop attack 1 | 11
Esophagitis 1 | 35
External Ophthalmoplegia 1 | 6
Febrile Convulsions 1 | 14
Focal Clonic Seizures 1 | 9
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 1 1 | 7
Generalized epilepsy with febrile seizures plus 1 | 7
Granulomatous amebic encephalitis 1 | 8
Growth hormone excess 1 | 14
HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1 1 | 2
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemia, fasting 1 | 7
Hyperkalemia 1 | 17
Hypokalemic periodic paralysis 1 1 | 2
Hypotonic seizures 1 | 11
Increased serum parathyroid hormone 1 | 14
Insulinoma 1 | 24
Multiple Endocrine Neoplasia Type 1 1 | 29
Muscle Cramp 1 | 55
Muscular stiffness 1 | 12
Myalgia 1 | 54
Myasthenias 1 | 8
Myasthenic Syndromes, Congenital 1 | 16
Non-Functioning Pituitary Gland Neoplasm 1 | 6
Parathyroid Adenoma 1 | 19
Parathyroid hyperplasia 1 | 6
Peptic Ulcer 1 | 27
Photosensitivity of skin 1 | 51
Pituitary growth hormone cell adenoma 1 | 8
Poisoning 1 | 16
Prolactinoma 1 | 11
Rimmed vacuoles on biopsy 1 | 15
Seizures, Febrile 1 | 7
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Subcutaneous lipomas 1 | 9
Sudden Infant Death 1 | 4
Thyroid Gland Follicular Adenoma 1 | 9
Tonic - clonic seizures 1 | 44
Trigeminal Neuralgia 1 | 24
Zollinger-Ellison syndrome 1 | 18
intermittent abdominal pain 1 | 9
periodic paralysis (finding) 1 | 3

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Liver and Pancreas 11 | 16,750
Cardiovascular System 10 | 15,192
Nervous System 10 | 16,725
Respiratory system 10 | 16,393

Target Family

Non-IDG 5 | 12,091
Enzyme 3 | 4,145
Ion Channel 3 | 344
Transcription Factor 1 | 1,400

Jensen-TM Tissue

SKM-1 12 | 12
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Beta-2-syntrophin SNTB2 Tbio Non-IDG -1.20042 14.7 121
Pre-mRNA-processing factor 17 CDC40 Tbio Non-IDG -1.37680 24.3 102
Chloride channel protein 1 CLCN1 Tbio Ion Channel -2.41484 252.7 89
Sodium channel protein type 4 subunit alpha SCN4A Tclin Ion Channel -2.57811 366.4 57
Sperm-associated antigen 6 SPAG6 Tbio Non-IDG -1.70662 51.2 111
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.16770 14.5 246
Cyclin-dependent kinase 4 inhibitor B CDKN2B Tbio Enzyme -2.61258 428.8 451
Sodium channel subunit beta-1 SCN1B Tbio Ion Channel -1.79728 56.1 151
Heterogeneous nuclear ribonucleoprotein D-like HNRNPDL Tbio Non-IDG -1.04203 11.1 104