Development Level

Tchem 35 | 1,890
Tbio 22 | 10,625
Tclin 11 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 4 | 260
increased lean body mass 3 | 107
abnormal behavior 2 | 226
abnormal tooth morphology 2 | 24
decreased grip strength 2 | 123
decreased rib number 2 | 59
decreased total body fat amoun... 2 | 186
decreased total retina thickne... 2 | 20
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased blood urea nitrogen ... 2 | 44
increased or absent threshold ... 2 | 128
persistence of hyaloid vascula... 2 | 22
abnormal coat/ hair morphology 1 | 18
abnormal coping response 1 | 12
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal limb position 1 | 3
abnormal maxilla morphology 1 | 16
abnormal nail morphology 1 | 7
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal inner nuclear... 1 | 5
abnormal retinal vasculature m... 1 | 15
abnormal snout morphology 1 | 18
abnormal tail morphology 1 | 17
absent startle reflex 1 | 15
absent teeth 1 | 4
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
edema 1 | 11
hemorrhage 1 | 12
hydrops fetalis 1 | 22
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
polycystic kidney 1 | 9
premature death 1 | 5
respiratory system phenotype 1 | 2
tail dragging 1 | 1

Disease

Toxic encephalopathy 47 | 131
Alzheimer's disease 46 | 644
Cancer 45 | 2,346
ovarian cancer 42 | 8,484
Parkinson's disease 35 | 364
glioblastoma 34 | 5,572
osteosarcoma 34 | 7,933
lung cancer 30 | 4,466
medulloblastoma, large-cell 30 | 6,234
psoriasis 30 | 6,685
atypical teratoid / rhabdoid tumor 27 | 4,369
diabetes mellitus 27 | 1,663
Dementia 24 | 129
Neurodegenerative disease 24 | 383
Vascular disease 23 | 281
Brain disease 20 | 83
malignant mesothelioma 19 | 3,162
oligodendroglioma 18 | 2,849
Breast cancer 16 | 3,094
Obesity 16 | 616
lung carcinoma 16 | 2,844
pilocytic astrocytoma 16 | 3,086
Pick disease 15 | 1,893
invasive ductal carcinoma 15 | 2,950
pediatric high grade glioma 15 | 2,712
Amyotrophic Lateral Sclerosis 14 | 431
Kidney disease 14 | 396
Nerve Degeneration 14 | 73
Parkinson Disease 14 | 102
Schizophrenia 14 | 501
astrocytoma 14 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
lung adenocarcinoma 14 | 2,713
ulcerative colitis 14 | 2,087
Mammary Neoplasms 13 | 410
Multiple myeloma 13 | 1,327
acute quadriplegic myopathy 13 | 1,157
ependymoma 13 | 2,514
pancreatic cancer 13 | 2,300
primitive neuroectodermal tumor 13 | 3,031
Down syndrome 12 | 548
Heart disease 12 | 279
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
non-small cell lung cancer 12 | 2,798
Cerebrovascular disease 11 | 231
Prostatic Neoplasms 11 | 471
Status Epilepticus 11 | 85
breast carcinoma 11 | 1,614
group 4 medulloblastoma 11 | 1,875
sonic hedgehog group medulloblastoma 11 | 1,482
Brain Ischemia 10 | 87
Lung Neoplasms 10 | 171
Myocardial Infarction 10 | 126
Parkinsonian Disorders 10 | 23
Stomach Neoplasms 10 | 282
interstitial cystitis 10 | 2,299
subependymal giant cell astrocytoma 10 | 2,287
Arthritis 9 | 248
Autistic Disorder 9 | 320
Cocaine-Related Disorders 9 | 88
Huntington's disease 9 | 72
Hyperglycemia 9 | 120
Neuroblastoma 9 | 78
Peripheral Neuropathy 9 | 303
Rheumatoid Arthritis 9 | 1,160
medulloblastoma 9 | 1,524
pituitary cancer 9 | 1,972
tuberculosis 9 | 1,557
Asthma 8 | 349
Bipolar Disorder 8 | 266
Carcinoma 8 | 2,147
Eye disease 8 | 55
Liver carcinoma 8 | 217
Lung disease 8 | 132
Multiple system atrophy 8 | 27
Neurodegenerative Disorders 8 | 37
adrenocortical carcinoma 8 | 1,427
adult high grade glioma 8 | 2,148
colon cancer 8 | 1,475
juvenile dermatomyositis 8 | 1,189
nervous system disorder 8 | 53
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Alcohol dependence 7 | 107
Amphetamine-Related Disorders 7 | 74
Amyloidosis 7 | 68
Diabetes Mellitus, Experimental 7 | 106
Duchenne muscular dystrophy 7 | 602
Intellectual disability 7 | 573
Learning Disorders 7 | 27
Major Depressive Disorder 7 | 106
Necrosis 7 | 51
Neuropathy 7 | 210
astrocytic glioma 7 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
cystic fibrosis 7 | 1,665
dermatomyositis 7 | 933
non-small cell lung carcinoma 7 | 413
posterior fossa group B ependymoma 7 | 1,530
Attention deficit hyperactivity disorder 6 | 156

Tissue

Digestive Tract 69 | 18,473
Endocrine System 69 | 18,512
Female tissues 69 | 18,647
Blood and immune system 68 | 17,995
Liver and Pancreas 68 | 18,136
Male tissues 68 | 17,969
Nervous System 68 | 18,561
Skin and soft tissues 68 | 18,115
Urinary Tract 68 | 18,444
Cardiovascular System 67 | 17,958
Respiratory system 67 | 17,484

Target Family

Non-IDG 26 | 11,971
Enzyme 18 | 4,146
Kinase 11 | 634
Transcription Factor 6 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 406
Ion Channel 1 | 341

Jensen-TM Tissue

SH-SY5Y cell 69 | 69
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
Mu-type opioid receptor OPRM1 Tclin GPCR -3.20440 1609.2 372
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
Cytochrome c CYCS Tbio Non-IDG -3.73952 4771.4 630
Glutamate--cysteine ligase catalytic subunit GCLC Tchem Enzyme -2.40511 266.2 257
Major facilitator superfamily domain-containing protein 12 MFSD12 Tdark Non-IDG 0.00000 1.00 41
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.02975 1184.8 589
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84502 678.2 177