Development Level

Tchem 32 | 1,388
Tbio 28 | 11,651
Tclin 13 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
decreased basophil cell number 2 | 16
decreased mean platelet volume 2 | 25
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal coat- hair morphology 1 | 19
abnormal digit morphology 1 | 10
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal limb morphology 1 | 13
abnormal limb position 1 | 3
abnormal nail morphology 1 | 8
abnormal retinal inner nuclear... 1 | 8
abnormal rib morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
respiratory system phenotype 1 | 2

Disease

Carcinoma 53 | 11,493
Toxic encephalopathy 53 | 141
Alzheimer's disease 49 | 658
Cancer 47 | 2,499
ovarian cancer 47 | 8,520
glioblastoma 39 | 5,792
Parkinson's disease 38 | 392
lung cancer 37 | 4,740
osteosarcoma 37 | 7,950
Schizophrenia 34 | 1,160
medulloblastoma, large-cell 34 | 6,241
atypical teratoid / rhabdoid tumor 32 | 5,112
psoriasis 32 | 6,694
diabetes mellitus 31 | 1,728
ependymoma 28 | 4,679
Neurodegenerative disease 27 | 414
Dementia 26 | 175
Vascular disease 26 | 319
Depressive disorder 24 | 409
malignant mesothelioma 24 | 3,232
Brain disease 23 | 96
Obesity 23 | 678
Bipolar Disorder 21 | 666
Breast cancer 21 | 3,578
group 3 medulloblastoma 20 | 4,104
Mental Depression 19 | 333
adult high grade glioma 19 | 3,801
oligodendroglioma 19 | 2,850
lung carcinoma 18 | 2,843
Astrocytoma, Pilocytic 17 | 3,081
Nerve Degeneration 17 | 121
Pick disease 17 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 17 | 2,951
lung adenocarcinoma 17 | 2,716
Amyotrophic lateral sclerosis 16 | 451
Parkinson Disease 16 | 64
Parkinsonian Disorders 16 | 56
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
pancreatic cancer 16 | 2,398
Alcoholic Intoxication, Chronic 15 | 289
Autosomal recessive predisposition 15 | 1,442
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
breast carcinoma 15 | 1,638
Heart disease 14 | 306
Kidney disease 14 | 430
Mood Disorders 14 | 184
Multiple myeloma 14 | 1,332
acute quadriplegic myopathy 14 | 1,158
non-small cell lung cancer 14 | 2,890
primitive neuroectodermal tumor 14 | 3,035
Alzheimer Disease 13 | 83
Cerebrovascular disease 13 | 238
Down syndrome 13 | 499
Intellectual disability 13 | 1,016
Major Depressive Disorder 13 | 301
Prostatic Neoplasms 13 | 495
Hyperglycemia 12 | 137
Seizures 12 | 596
astrocytic glioma 12 | 2,597
astrocytoma 12 | 1,146
interstitial cystitis 12 | 2,312
subependymal giant cell astrocytoma 12 | 2,287
Asthma 11 | 385
Brain Ischemia 11 | 110
Huntington's disease 11 | 76
Kidney cancer 11 | 2,613
Lung Neoplasms 11 | 232
Myocardial Infarction 11 | 151
Status Epilepticus 11 | 98
Stomach Neoplasms 11 | 300
Unipolar Depression 11 | 250
tuberculosis 11 | 2,010
Arthritis 10 | 290
Cocaine-Related Disorders 10 | 92
Epilepsy 10 | 792
Eye disease 10 | 62
Neuroblastoma 10 | 80
Neuropathy 10 | 261
group 4 medulloblastoma 10 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 1,819
Attention deficit hyperactivity disorder 9 | 278
Autistic Disorder 9 | 364
Diabetes Mellitus, Experimental 9 | 108
Hypertension 9 | 396
Liver Cirrhosis, Experimental 9 | 769
Liver disease 9 | 237
Multiple system atrophy 9 | 29
Nervous System Diseases 9 | 53
Neurodegenerative Disorders 9 | 79
Rheumatoid arthritis 9 | 1,191
adrenocortical carcinoma 9 | 1,428
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
nervous system disorder 9 | 53
Dull intelligence 8 | 645

Tissue

Endocrine System 72 | 18,159
Female tissues 72 | 17,400
Liver and Pancreas 71 | 16,750
Blood and immune system 70 | 16,909
Digestive Tract 70 | 17,369
Male tissues 70 | 17,142
Nervous System 70 | 16,725
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Respiratory system 67 | 16,393
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 22 | 4,145
Kinase 12 | 634
Transcription Factor 6 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Ion Channel 1 | 344

Jensen-TM Tissue

SH-SY5Y cell 74 | 74
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
Synphilin-1 SNCAIP Tbio Non-IDG -1.92755 92.1 157
Neuropeptide FF receptor 2 NPFFR2 Tchem GPCR -1.63803 38.0 161
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.66223 525.4 1185
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045