Development Level

Tbio 195 | 10,625
Tchem 67 | 1,890
Tclin 30 | 602
Tdark 9 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 8 | 633
preweaning lethality, incomple... 8 | 260
decreased body weight 6 | 174
decreased grip strength 6 | 123
limb grasping 6 | 35
abnormal behavior 5 | 226
abnormal retina morphology 5 | 100
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
abnormal bone mineralization 4 | 55
decreased circulating HDL chol... 4 | 77
decreased circulating amylase ... 4 | 24
decreased circulating choleste... 4 | 85
decreased circulating triglyce... 4 | 83
enlarged heart 4 | 111
increased fasted circulating g... 4 | 68
abnormal bone structure 3 | 131
decreased circulating alkaline... 3 | 41
decreased circulating potassiu... 3 | 17
decreased prepulse inhibition 3 | 52
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
hyperactivity 3 | 108
hypoactivity 3 | 89
increased blood urea nitrogen ... 3 | 44
increased circulating alkaline... 3 | 119
increased circulating chloride... 3 | 43
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
abnormal QRS complex 2 | 25
abnormal heart morphology 2 | 51
abnormal respiratory quotient 2 | 9
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
absent pinna reflex 2 | 21
cardiovascular system phenotyp... 2 | 35
decreased body length 2 | 108
decreased circulating calcium ... 2 | 33
decreased circulating glycerol... 2 | 19
decreased circulating insulin ... 2 | 75
impaired pupillary reflex 2 | 14
impaired righting response 2 | 19
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 36
increased mean corpuscular vol... 2 | 91
increased rib number 2 | 41
increased total body fat amoun... 2 | 57
mydriasis 2 | 9
stereotypic behavior 2 | 3
straub tail 2 | 26
tremors 2 | 34
trunk curl 2 | 15
vertebral fusion 2 | 23
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal whole-body plethysmog... 1 | 4
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
female infertility 1 | 34
hydrops fetalis 1 | 22
increased NK T cell number 1 | 11
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased mean platelet volume 1 | 19
increased respiratory quotient 1 | 12
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
short tibia 1 | 82
thrombocytosis 1 | 23

Disease

psoriasis 128 | 6,685
Cancer 119 | 2,346
medulloblastoma, large-cell 118 | 6,234
ovarian cancer 117 | 8,484
glioblastoma 115 | 5,572
lung cancer 96 | 4,466
osteosarcoma 96 | 7,933
atypical teratoid / rhabdoid tumor 87 | 4,369
pilocytic astrocytoma 83 | 3,086
malignant mesothelioma 79 | 3,162
oligodendroglioma 76 | 2,849
primitive neuroectodermal tumor 71 | 3,031
lung carcinoma 69 | 2,844
diabetes mellitus 67 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,289
lung adenocarcinoma 61 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,956
Retinitis pigmentosa 57 | 153
intraductal papillary-mucinous carcinoma (IPMC) 57 | 2,988
cystic fibrosis 56 | 1,665
ependymoma 56 | 2,514
pediatric high grade glioma 56 | 2,712
Breast cancer 55 | 3,094
pituitary cancer 55 | 1,972
Alzheimer's disease 53 | 644
astrocytic glioma 53 | 2,241
non-small cell lung cancer 52 | 2,798
invasive ductal carcinoma 51 | 2,950
Cerebrovascular disease 50 | 231
group 4 medulloblastoma 50 | 1,875
Blindness 49 | 84
ulcerative colitis 49 | 2,087
Carcinoma 48 | 2,147
Toxic encephalopathy 48 | 131
Kidney disease 47 | 396
Obesity 47 | 616
pancreatic cancer 47 | 2,300
subependymal giant cell astrocytoma 44 | 2,287
group 3 medulloblastoma 43 | 2,254
Heart disease 42 | 279
adult high grade glioma 42 | 2,148
interstitial cystitis 41 | 2,299
Fundus dystrophy 40 | 77
Schizophrenia 40 | 501
Vascular disease 40 | 281
posterior fossa group A ependymoma 39 | 1,511
Hypertension 38 | 287
Pick disease 38 | 1,893
adrenocortical carcinoma 38 | 1,427
Parkinson's disease 37 | 364
astrocytoma 37 | 1,493
sonic hedgehog group medulloblastoma 37 | 1,482
Epilepsy 36 | 346
Neurodegenerative disease 36 | 383
Eye disease 34 | 55
Retinal Degeneration 34 | 49
Cone dystrophy 33 | 57
breast carcinoma 33 | 1,614
ductal carcinoma in situ 33 | 1,745
tuberculosis 33 | 1,557
Leber congenital amaurosis 31 | 72
colon cancer 31 | 1,475
posterior fossa group B ependymoma 31 | 1,530
Night Blindness 30 | 39
Arthritis 29 | 248
Diabetic Retinopathy 29 | 53
Down syndrome 29 | 548
Glaucoma 29 | 134
Mammary Neoplasms 29 | 410
Multiple Sclerosis 29 | 498
Asthma 28 | 349
Neuropathy 28 | 210
primary pancreatic ductal adenocarcinoma 28 | 1,271
Brain Ischemia 27 | 87
Brain disease 27 | 83
Liver disease 27 | 219
atypical teratoid/rhabdoid tumor 27 | 1,095
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
Endometriosis 26 | 535
Intellectual disability 26 | 573
Prostatic Neoplasms 26 | 471
gastric carcinoma 26 | 832
Amyotrophic Lateral Sclerosis 25 | 431
Atherosclerosis 25 | 275
Rheumatoid Arthritis 25 | 1,160
Stomach Neoplasms 25 | 282
Inflammatory bowel disease 24 | 142
Age related macular degeneration 23 | 84
Hyperglycemia 23 | 120
Reperfusion Injury 23 | 84
cone-rod dystrophy 23 | 56
medulloblastoma 23 | 1,524
Inflammation 22 | 109
Lung disease 22 | 132
Status Epilepticus 22 | 85
dermatomyositis 21 | 933
Coronary artery disease 20 | 240
Dementia 20 | 129
Autistic Disorder 19 | 320
nasopharyngeal carcinoma 19 | 1,056

Tissue

Nervous System 295 | 18,561
Digestive Tract 292 | 18,473
Endocrine System 292 | 18,512
Female tissues 291 | 18,647
Skin and soft tissues 289 | 18,115
Urinary Tract 288 | 18,444
Blood and immune system 286 | 17,995
Cardiovascular System 286 | 17,958
Liver and Pancreas 286 | 18,136
Male tissues 279 | 17,969
Respiratory system 274 | 17,484

Target Family

Non-IDG 167 | 11,971
Enzyme 51 | 4,146
Transcription Factor 31 | 1,400
Kinase 18 | 634
Ion Channel 15 | 341
GPCR 9 | 406
Transporter 8 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Retina 301 | 301
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Pancreas transcription factor 1 subunit alpha PTF1A Tbio Transcription Factor -2.56282 377.5 283
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401