Development Level

Tbio 231 | 11,651
Tchem 55 | 1,388
Tclin 37 | 612
Tdark 7 | 6,593

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 9 | 298
decreased vertical activity 6 | 208
enlarged heart 6 | 210
limb grasping 6 | 41
decreased body weight 5 | 161
hyperactivity 5 | 148
increased total body fat amoun... 5 | 134
abnormal heart morphology 4 | 162
decreased circulating amylase ... 4 | 28
decreased grip strength 4 | 116
embryonic lethality prior to t... 4 | 278
increased fasted circulating g... 4 | 76
increased lean body mass 4 | 172
increased startle reflex 4 | 112
abnormal bone mineralization 3 | 38
abnormal eye morphology 3 | 68
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased circulating alkaline... 3 | 46
decreased circulating potassiu... 3 | 20
decreased circulating triglyce... 3 | 79
hypoactivity 3 | 132
increased circulating sodium l... 3 | 71
increased hematocrit 3 | 46
increased mean corpuscular hem... 3 | 96
increased or absent threshold ... 3 | 101
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal pericardium morpholog... 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal vibrissa morphology 2 | 25
absent pinna reflex 2 | 23
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating calcium ... 2 | 36
decreased circulating creatini... 2 | 39
decreased circulating glycerol... 2 | 16
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
enlarged uterus 2 | 11
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased circulating iron lev... 2 | 30
increased heart rate 2 | 23
increased mean corpuscular vol... 2 | 92
increased thermal nociceptive ... 2 | 9
mammalian phenotype 2 | 17
premature death 2 | 5
prolonged PR interval 2 | 15
short tibia 2 | 97
shortened RR interval 2 | 17
stereotypic behavior 2 | 3
tremors 2 | 39
trunk curl 2 | 16
vertebral fusion 2 | 23
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 219 | 11,493
psoriasis 140 | 6,694
Cancer 135 | 2,499
ovarian cancer 133 | 8,520
glioblastoma 129 | 5,792
medulloblastoma, large-cell 129 | 6,241
ependymoma 117 | 4,679
lung cancer 112 | 4,740
atypical teratoid / rhabdoid tumor 109 | 5,112
osteosarcoma 108 | 7,950
group 3 medulloblastoma 97 | 4,104
Schizophrenia 92 | 1,160
Astrocytoma, Pilocytic 88 | 3,081
malignant mesothelioma 88 | 3,232
adult high grade glioma 83 | 3,801
oligodendroglioma 82 | 2,850
diabetes mellitus 79 | 1,728
Obesity 76 | 678
lung carcinoma 76 | 2,843
Breast cancer 73 | 3,578
primitive neuroectodermal tumor 73 | 3,035
Intellectual disability 72 | 1,016
Autosomal recessive predisposition 70 | 1,442
astrocytic glioma 70 | 2,597
Epilepsy 66 | 792
Alzheimer's disease 65 | 658
lung adenocarcinoma 65 | 2,716
Glaucoma 64 | 239
Retinitis Pigmentosa 64 | 226
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
Cataract 62 | 297
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,989
pituitary cancer 61 | 1,972
Kidney cancer 60 | 2,613
Bipolar Disorder 58 | 666
non-small cell lung cancer 57 | 2,890
Cerebrovascular disease 56 | 238
Dull intelligence 56 | 645
Low intelligence 56 | 645
Mental Retardation 56 | 645
Mental deficiency 56 | 645
Night Blindness 56 | 101
Poor school performance 56 | 645
Toxic encephalopathy 56 | 141
cystic fibrosis 56 | 1,696
Nystagmus 55 | 317
Retinal Degeneration 54 | 106
invasive ductal carcinoma 54 | 2,951
Blindness 53 | 88
Depressive disorder 53 | 409
Kidney disease 53 | 430
Lens Opacities 53 | 231
pancreatic cancer 52 | 2,398
Heart disease 50 | 306
Vascular disease 50 | 319
Hypertension 49 | 396
Seizures 48 | 596
Difficulties with night vision 47 | 87
subependymal giant cell astrocytoma 47 | 2,287
Electroretinogram abnormal 46 | 95
Mental Depression 46 | 333
Sensorineural Hearing Loss (disorder) 46 | 284
interstitial cystitis 46 | 2,312
Abnormality of retinal pigmentation 45 | 111
Low Vision 45 | 174
Retinal pigment epithelial abnormality 45 | 111
Visual Impairment 45 | 174
Fundus dystrophy 43 | 83
Neurodegenerative disease 43 | 414
Photodysphoria 43 | 121
Photophobia 43 | 121
Parkinson's disease 42 | 392
ulcerative colitis 42 | 1,819
Hyperinsulinism 41 | 133
tuberculosis 41 | 2,010
Pick disease 40 | 1,894
group 4 medulloblastoma 40 | 1,855
Cone dystrophy 39 | 71
Eye disease 39 | 62
adrenocortical carcinoma 39 | 1,428
Blind Vision 38 | 111
Broad flat nasal bridge 38 | 236
Nasal bridge wide 38 | 236
Blindness, Legal 37 | 110
Congenital hypoplasia of penis 37 | 176
Neuropathy 37 | 261
breast carcinoma 37 | 1,638
Myopia 35 | 176
Optic Atrophy 35 | 242
colon cancer 35 | 1,478
ductal carcinoma in situ 35 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Keratoconus 34 | 113
Melanoma 34 | 711
Anteverted nostril 33 | 191
Arthritis 33 | 290
Breast Neoplasms 33 | 445
Hypogonadism 33 | 173
Reduced visual acuity 33 | 63

Tissue

Endocrine System 316 | 18,159
Digestive Tract 293 | 17,369
Nervous System 293 | 16,725
Skin and soft tissues 290 | 17,230
Female tissues 289 | 17,400
Male tissues 280 | 17,142
Blood and immune system 279 | 16,909
Liver and Pancreas 276 | 16,750
Urinary Tract 269 | 16,678
Respiratory system 259 | 16,393
Cardiovascular System 233 | 15,192

Target Family

Non-IDG 181 | 12,091
Enzyme 54 | 4,145
Transcription Factor 34 | 1,400
Kinase 19 | 634
Ion Channel 17 | 344
GPCR 13 | 408
Transporter 10 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Retina 330 | 330
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Homeobox protein SIX6 SIX6 Tbio Transcription Factor -2.23077 163.2 112
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
Opsin-5 OPN5 Tbio GPCR -1.19753 14.2 151
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075