Development Level

Tchem 53 | 1,388
Tbio 52 | 11,651
Tclin 21 | 612
Tdark 3 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 6 | 278
enlarged heart 6 | 210
embryonic lethality prior to o... 4 | 239
increased circulating choleste... 4 | 66
increased mean corpuscular hem... 4 | 96
small superior vagus ganglion 4 | 74
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
abnormal spleen morphology 3 | 55
cataract 3 | 92
decreased circulating insulin ... 3 | 76
increased circulating HDL chol... 3 | 80
increased total body fat amoun... 3 | 134
male infertility 3 | 123
abnormal behavior 2 | 298
abnormal eye morphology 2 | 68
abnormal head morphology 2 | 10
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
female infertility 2 | 60
hydrometra 2 | 53
increased caudal vertebrae num... 2 | 7
increased hemoglobin content 2 | 45
short tibia 2 | 97
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
scaly skin 1 | 4
small spleen 1 | 19
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Cancer 116 | 2,499
ovarian cancer 96 | 8,520
Carcinoma 90 | 11,493
psoriasis 80 | 6,694
glioblastoma 78 | 5,792
osteosarcoma 75 | 7,950
lung cancer 73 | 4,740
Breast cancer 68 | 3,578
atypical teratoid / rhabdoid tumor 63 | 5,112
Prostatic Neoplasms 56 | 495
malignant mesothelioma 56 | 3,232
Breast Neoplasms 55 | 445
Mammary Neoplasms 54 | 425
medulloblastoma, large-cell 53 | 6,241
pancreatic cancer 52 | 2,398
non-small cell lung cancer 51 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
lung adenocarcinoma 47 | 2,716
ependymoma 46 | 4,679
diabetes mellitus 45 | 1,728
invasive ductal carcinoma 45 | 2,951
Astrocytoma, Pilocytic 43 | 3,081
breast carcinoma 43 | 1,638
oligodendroglioma 41 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
Neoplasm Metastasis 38 | 168
Stomach Neoplasms 38 | 300
adult high grade glioma 38 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
Vascular disease 37 | 319
ulcerative colitis 37 | 1,819
lung carcinoma 36 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
Carcinoma, Hepatocellular 33 | 228
Liver carcinoma 33 | 240
Schizophrenia 33 | 1,160
ductal carcinoma in situ 33 | 1,745
interstitial cystitis 33 | 2,312
primitive neuroectodermal tumor 33 | 3,035
tuberculosis 33 | 2,010
Kidney cancer 32 | 2,613
Kidney disease 32 | 430
subependymal giant cell astrocytoma 32 | 2,287
colon cancer 31 | 1,478
group 3 medulloblastoma 31 | 4,104
adrenocortical carcinoma 30 | 1,428
Neoplasm Invasiveness 29 | 161
Obesity 29 | 678
astrocytoma 29 | 1,146
cystic fibrosis 29 | 1,696
pituitary cancer 28 | 1,972
Liver Cirrhosis, Experimental 26 | 769
acute quadriplegic myopathy 26 | 1,158
Arthritis 24 | 290
Endometriosis 24 | 540
Heart disease 24 | 306
Lung Neoplasms 24 | 232
Alzheimer's disease 23 | 658
Autosomal recessive predisposition 23 | 1,442
Pancreatic Neoplasm 23 | 85
Squamous cell carcinoma 23 | 129
juvenile dermatomyositis 23 | 1,187
nasopharyngeal carcinoma 23 | 1,058
Adenocarcinoma 22 | 122
Adenoma 22 | 167
Pancreatic Neoplasms 22 | 85
astrocytic glioma 22 | 2,597
Bipolar Disorder 21 | 666
Carcinoma, Squamous Cell 21 | 110
Cell Transformation, Neoplastic 21 | 97
Liver disease 21 | 237
Ovarian Neoplasms 21 | 102
Rheumatoid arthritis 21 | 1,191
Toxic encephalopathy 21 | 141
ovarian neoplasm 21 | 99
Asthma 20 | 385
Atopic dermatitis 20 | 952
Colonic Neoplasms 20 | 142
Colorectal Neoplasms 20 | 243
Melanoma 20 | 711
acute myeloid leukemia 20 | 783
pediatric high grade glioma 20 | 1,064
Multiple myeloma 19 | 1,332
Neoplastic Cell Transformation 19 | 89
primary pancreatic ductal adenocarcinoma 19 | 1,109
Bladder Neoplasm 18 | 112
Multiple Sclerosis 18 | 540
Neurodegenerative disease 18 | 414
Prostate cancer 18 | 175
Urinary Bladder Neoplasms 18 | 114
group 4 medulloblastoma 18 | 1,855
medulloblastoma 18 | 720
Eye disease 17 | 62
Hypertension 17 | 396
Lung disease 17 | 142
Mammary Neoplasms, Experimental 17 | 154
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
hepatocellular carcinoma 17 | 547
Duchenne muscular dystrophy 16 | 601
dermatomyositis 16 | 966

Tissue

Digestive Tract 125 | 17,369
Endocrine System 125 | 18,159
Blood and immune system 124 | 16,909
Female tissues 123 | 17,400
Liver and Pancreas 123 | 16,750
Male tissues 123 | 17,142
Nervous System 123 | 16,725
Skin and soft tissues 123 | 17,230
Urinary Tract 122 | 16,678
Respiratory system 121 | 16,393
Cardiovascular System 116 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 32 | 4,145
Kinase 21 | 634
Transcription Factor 13 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 3 | 48
Ion Channel 2 | 344
GPCR 1 | 408

Jensen-TM Tissue

Prostate cancer cell line 129 | 129
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Nuclear receptor coactivator 4 NCOA4 Tbio Non-IDG -2.20245 136.0 283
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Prostate stem cell antigen PSCA Tbio Non-IDG -2.40263 274.6 299