Development Level

Tchem 59 | 1,890
Tbio 38 | 10,625
Tclin 20 | 602
Tdark 4 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
embryonic lethality prior to t... 5 | 187
enlarged heart 4 | 111
decreased circulating insulin ... 3 | 75
embryonic lethality prior to o... 3 | 148
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal head morphology 2 | 10
abnormal lens morphology 2 | 73
abnormal spleen morphology 2 | 36
cataract 2 | 26
decreased grip strength 2 | 123
decreased total body fat amoun... 2 | 186
increased circulating triglyce... 2 | 24
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal cranium morphology 1 | 32
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal urinary bladder morph... 1 | 2
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating creatini... 1 | 31
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased monocyte cell number 1 | 28
decreased total retina thickne... 1 | 20
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased aggression 1 | 2
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating glycerol... 1 | 11
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
microphthalmia 1 | 15
prolonged PR interval 1 | 4
small superior vagus ganglion 1 | 20
small testis 1 | 37
urinary bladder obstruction 1 | 2

Disease

Cancer 106 | 2,346
ovarian cancer 87 | 8,484
psoriasis 76 | 6,685
glioblastoma 73 | 5,572
osteosarcoma 69 | 7,933
lung cancer 66 | 4,466
Breast cancer 55 | 3,094
Prostatic Neoplasms 54 | 471
atypical teratoid / rhabdoid tumor 49 | 4,369
Mammary Neoplasms 48 | 410
malignant mesothelioma 48 | 3,162
medulloblastoma, large-cell 48 | 6,234
non-small cell lung cancer 48 | 2,798
pancreatic cancer 47 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,289
lung adenocarcinoma 43 | 2,713
invasive ductal carcinoma 42 | 2,950
pilocytic astrocytoma 42 | 3,086
pediatric high grade glioma 41 | 2,712
diabetes mellitus 39 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
oligodendroglioma 39 | 2,849
ulcerative colitis 39 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
lung carcinoma 36 | 2,844
Vascular disease 35 | 281
breast carcinoma 35 | 1,614
Neoplasm Metastasis 34 | 138
Stomach Neoplasms 33 | 282
interstitial cystitis 32 | 2,299
primitive neuroectodermal tumor 32 | 3,031
ductal carcinoma in situ 31 | 1,745
subependymal giant cell astrocytoma 31 | 2,287
Kidney disease 30 | 396
Liver carcinoma 29 | 217
astrocytoma 29 | 1,493
colon cancer 29 | 1,475
cystic fibrosis 29 | 1,665
tuberculosis 29 | 1,557
adrenocortical carcinoma 28 | 1,427
Carcinoma 27 | 2,147
Obesity 27 | 616
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
pituitary cancer 27 | 1,972
Lung Neoplasms 26 | 171
Endometriosis 24 | 535
Neoplasm Invasiveness 24 | 127
acute quadriplegic myopathy 24 | 1,157
Adenoma 23 | 165
primary pancreatic ductal adenocarcinoma 23 | 1,271
Alzheimer's disease 22 | 644
Heart disease 22 | 279
juvenile dermatomyositis 22 | 1,189
nasopharyngeal carcinoma 22 | 1,056
Arthritis 21 | 248
Pancreatic Neoplasm 21 | 79
Rheumatoid Arthritis 21 | 1,160
ependymoma 21 | 2,514
posterior fossa group A ependymoma 21 | 1,511
Adenocarcinoma 20 | 115
Liver disease 20 | 219
Multiple myeloma 20 | 1,327
Prostate cancer 20 | 172
Toxic encephalopathy 20 | 131
ovarian neoplasm 20 | 97
Colorectal Neoplasms 19 | 217
acute myeloid leukemia 19 | 780
Asthma 18 | 349
Colonic Neoplasms 18 | 126
Lung disease 18 | 132
medulloblastoma 18 | 1,524
Atopic dermatitis 17 | 944
Bladder Neoplasm 17 | 109
Melanoma 17 | 261
Neoplastic Cell Transformation 17 | 81
Squamous cell carcinoma 17 | 94
astrocytic glioma 17 | 2,241
gastric carcinoma 17 | 832
group 4 medulloblastoma 17 | 1,875
sonic hedgehog group medulloblastoma 17 | 1,482
Atherosclerosis 16 | 275
Mammary Neoplasms, Experimental 16 | 150
Peripheral Neuropathy 16 | 303
Reperfusion Injury 16 | 84
adult high grade glioma 16 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
Brain Ischemia 15 | 87
Duchenne muscular dystrophy 15 | 602
dermatomyositis 15 | 933
group 3 medulloblastoma 15 | 2,254
non-small cell lung carcinoma 15 | 413
Eye disease 14 | 55
Inflammatory bowel disease 14 | 142
Multiple Sclerosis 14 | 498
Myocardial Infarction 14 | 126
Osteoporosis 14 | 257
Parkinson's disease 14 | 364
Neurodegenerative disease 13 | 383
Pick disease 13 | 1,893
esophageal adenocarcinoma 13 | 737

Tissue

Endocrine System 118 | 18,512
Liver and Pancreas 118 | 18,136
Digestive Tract 117 | 18,473
Female tissues 117 | 18,647
Male tissues 117 | 17,969
Nervous System 117 | 18,561
Skin and soft tissues 117 | 18,115
Urinary Tract 117 | 18,444
Blood and immune system 116 | 17,995
Cardiovascular System 116 | 17,958
Respiratory system 116 | 17,484

Target Family

Non-IDG 50 | 11,971
Enzyme 32 | 4,146
Kinase 20 | 634
Transcription Factor 11 | 1,400
Epigenetic 3 | 242
Ion Channel 2 | 341
Nuclear Receptor 2 | 48
GPCR 1 | 406

Jensen-TM Tissue

Prostate cancer cell line 121 | 121
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Fatty acid synthase FASN Tchem Enzyme -2.49948 348.5 388
Williams-Beuren syndrome chromosomal region 28 protein WBSCR28 Tdark Non-IDG 0.56 0.20 10
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129