Development Level

Tbio 86 | 10,625
Tchem 15 | 1,890
Tclin 2 | 602
Tdark 1 | 7,003

IMPC Phenotype

preweaning lethality, complete... 9 | 633
limb grasping 4 | 35
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal retina morphology 2 | 100
corneal opacity 2 | 25
decreased body weight 2 | 174
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
increased total body fat amoun... 2 | 57
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retinal outer nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
cleft palate 1 | 6
cyanosis 1 | 6
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased prepulse inhibition 1 | 52
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating glucose ... 1 | 16
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
irregularly shaped pupil 1 | 7
male infertility 1 | 62
narrow eye opening 1 | 15
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
prolonged QRS complex duration 1 | 2
rib fusion 1 | 2
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
small testis 1 | 37
syndactyly 1 | 4
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

Cancer 44 | 2,346
ovarian cancer 40 | 8,491
psoriasis 38 | 6,685
Infertility 34 | 163
medulloblastoma, large-cell 31 | 6,234
osteosarcoma 29 | 7,933
atypical teratoid / rhabdoid tumor 22 | 4,369
lung cancer 22 | 4,473
glioblastoma 21 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
malignant mesothelioma 19 | 3,163
Premature ovarian failure 18 | 64
cystic fibrosis 16 | 1,670
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
Breast cancer 15 | 3,098
non-small cell lung cancer 15 | 2,798
Cleft palate 14 | 125
ependymoma 14 | 2,514
invasive ductal carcinoma 14 | 2,950
Craniofacial Abnormalities 13 | 147
Male infertility 13 | 170
pilocytic astrocytoma 13 | 3,086
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,031
sonic hedgehog group medulloblastoma 13 | 1,482
Gonadoblastoma 12 | 27
lung carcinoma 12 | 2,844
oligodendroglioma 12 | 2,849
Alzheimer's disease 11 | 644
Mammary Neoplasms 11 | 410
group 4 medulloblastoma 11 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 11 | 2,714
pediatric high grade glioma 11 | 2,712
ulcerative colitis 11 | 2,087
Amenorrhea 10 | 60
Cleft Lip 10 | 91
Hypogonadism 10 | 70
diabetes mellitus 10 | 1,663
interstitial cystitis 10 | 2,299
pancreatic cancer 10 | 2,300
Carcinoma 9 | 2,147
Hypospadias 9 | 65
Osteoporosis 9 | 259
Ovarian dysfunction 9 | 19
Prostatic Neoplasms 9 | 471
astrocytic glioma 9 | 2,241
breast carcinoma 9 | 1,614
colon cancer 9 | 1,475
medulloblastoma 9 | 1,524
Azoospermia 8 | 89
Colorectal Neoplasms 8 | 217
Cryptorchidism 8 | 67
Endometriosis 8 | 535
Kidney disease 8 | 397
Klinefelter's syndrome 8 | 59
adrenocortical carcinoma 8 | 1,427
adult high grade glioma 8 | 2,148
cutaneous lupus erythematosus 8 | 1,056
ductal carcinoma in situ 8 | 1,745
tuberculosis 8 | 1,563
Female Urogenital Diseases 7 | 18
Microphthalmia 7 | 79
Pick disease 7 | 1,893
group 3 medulloblastoma 7 | 2,254
subependymal giant cell astrocytoma 7 | 2,287
Lung Neoplasms 6 | 171
Microcephaly 6 | 149
Obesity 6 | 616
Parkinson's disease 6 | 364
Polycystic Ovary Syndrome 6 | 334
Polydactyly 6 | 93
astrocytoma 6 | 1,493
gastric carcinoma 6 | 832
posterior fossa group B ependymoma 6 | 1,530
primary pancreatic ductal adenocarcinoma 6 | 1,271
Adenoma 5 | 165
Arthritis 5 | 248
Coloboma 5 | 52
Diaphragmatic Hernia 5 | 40
Heart disease 5 | 279
Holoprosencephaly 5 | 52
Intellectual disability 5 | 573
Liver carcinoma 5 | 217
Liver disease 5 | 219
Myocardial Infarction 5 | 126
Neoplasms, Germ Cell and Embryonal 5 | 13
Oligospermia 5 | 30
Oophoritis 5 | 9
Pseudohermaphroditism 5 | 16
Seckel syndrome 5 | 35
Silver-Russell syndrome 5 | 37
Stomach Neoplasms 5 | 282
Synostosis 5 | 18
Testicular germ cell tumor 5 | 23
acute quadriplegic myopathy 5 | 1,157
fibroadenoma 5 | 557
mucosa-associated lymphoid tissue lymphoma 5 | 480
spina bifida 5 | 1,064
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795

Tissue

Endocrine System 103 | 18,511
Female tissues 102 | 18,646
Nervous System 99 | 18,560
Urinary Tract 99 | 18,443
Digestive Tract 98 | 18,472
Skin and soft tissues 98 | 18,114
Blood and immune system 96 | 17,994
Male tissues 96 | 17,968
Cardiovascular System 94 | 17,957
Liver and Pancreas 94 | 18,135
Respiratory system 84 | 17,483

Target Family

Non-IDG 52 | 11,969
Transcription Factor 36 | 1,400
Enzyme 7 | 4,146
Kinase 4 | 634
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Primordium 104 | 104
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.66256 471.8 306
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.28009 1980.8 817
Deleted in azoospermia protein 1 DAZ1 Tbio Non-IDG -2.24070 174.2 147
Atrophin-1 ATN1 Tbio Non-IDG -2.40264 232.0 102
Follistatin FST Tbio Non-IDG -3.06086 1100.8 305
Probable ATP-dependent RNA helicase DDX4 DDX4 Tbio Enzyme -1.87408 72.5 215
DNA replication factor Cdt1 CDT1 Tbio Non-IDG -2.17234 139.2 105
Homeobox protein MSX-2 MSX2 Tbio Transcription Factor -2.42775 269.0 283
Chorion-specific transcription factor GCMb GCM2 Tbio Transcription Factor -2.16084 139.6 65