Development Level

Tbio 87 | 11,651
Tchem 11 | 1,388
Tclin 3 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 9 | 979
increased total body fat amoun... 5 | 134
decreased bone mineral content 4 | 151
decreased lean body mass 4 | 135
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
embryonic lethality prior to t... 3 | 278
increased circulating HDL chol... 3 | 80
limb grasping 3 | 41
preweaning lethality, incomple... 3 | 499
abnormal gait 2 | 69
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
female infertility 2 | 60
hydrometra 2 | 53
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased hemoglobin content 2 | 45
increased startle reflex 2 | 112
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
athymia 1 | 2
cataract 1 | 92
cleft palate 1 | 8
cyanosis 1 | 7
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged urinary bladder 1 | 8
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small testis 1 | 58
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 58 | 11,493
Cancer 45 | 2,499
Infertility 40 | 188
ovarian cancer 37 | 8,520
psoriasis 36 | 6,694
medulloblastoma, large-cell 28 | 6,241
osteosarcoma 26 | 7,950
lung cancer 25 | 4,740
Autosomal recessive predisposition 22 | 1,442
Short stature 22 | 531
Male infertility 21 | 206
glioblastoma 21 | 5,792
malignant mesothelioma 21 | 3,232
Breast cancer 20 | 3,578
Premature ovarian failure 20 | 65
atypical teratoid / rhabdoid tumor 20 | 5,112
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
ependymoma 19 | 4,679
Cryptorchidism 18 | 296
Cleft Palate 17 | 271
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Kidney cancer 16 | 2,613
cystic fibrosis 15 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
non-small cell lung cancer 15 | 2,890
Craniofacial Abnormalities 14 | 151
Epilepsy 14 | 792
Osteoporosis 14 | 363
Astrocytoma, Pilocytic 13 | 3,081
Breast Neoplasms 13 | 445
Mammary Neoplasms 13 | 425
Polycystic ovary syndrome 13 | 360
Seizures 13 | 596
group 3 medulloblastoma 13 | 4,104
invasive ductal carcinoma 13 | 2,951
oligodendroglioma 13 | 2,850
pituitary cancer 13 | 1,972
Azoospermia 12 | 110
Gonadoblastoma 12 | 34
Intellectual disability 12 | 1,016
Muscle hypotonia 12 | 571
Strabismus 12 | 270
adult high grade glioma 12 | 3,801
breast carcinoma 12 | 1,638
Alzheimer's disease 11 | 658
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Primary physiologic amenorrhea 11 | 55
Prostatic Neoplasms 11 | 495
Small testicle 11 | 75
astrocytic glioma 11 | 2,597
group 4 medulloblastoma 11 | 1,855
lung carcinoma 11 | 2,843
primitive neuroectodermal tumor 11 | 3,035
Amenorrhea 10 | 58
Cleft Lip 10 | 141
Hypogonadism 10 | 173
Hypogonadism, Isolated Hypogonadotropic 10 | 71
Hypogonadotropic hypogonadism 10 | 89
Penile hypospadias 10 | 106
Schizophrenia 10 | 1,160
diabetes mellitus 10 | 1,728
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
pancreatic cancer 10 | 2,398
ulcerative colitis 10 | 1,819
Endometriosis 9 | 540
Gonadal Dysgenesis 9 | 28
Hypoplastic mandible condyle 9 | 275
Hypospadias 9 | 53
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Obesity 9 | 678
Ovarian dysfunction 9 | 18
Small head 9 | 374
lung adenocarcinoma 9 | 2,716
Cataract 8 | 297
Colorectal Neoplasms 8 | 243
Congenital hypoplasia of penis 8 | 176
Gonadal Dysgenesis, Mixed 8 | 19
Lens Opacities 8 | 231
Pure gonadal dysgenesis 8 | 19
Stomach Neoplasms 8 | 300
Streak ovary 8 | 15
Uranostaphyloschisis 8 | 167
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
sonic hedgehog group medulloblastoma 8 | 467
Abnormally small eyeball 7 | 97
Decreased size of eyeball 7 | 97
Delayed bone age 7 | 136
Vascular disease 7 | 319
ductal carcinoma in situ 7 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287

Tissue

Endocrine System 96 | 18,159
Female tissues 83 | 17,400
Digestive Tract 79 | 17,369
Male tissues 78 | 17,142
Skin and soft tissues 77 | 17,230
Nervous System 74 | 16,725
Blood and immune system 73 | 16,909
Respiratory system 69 | 16,393
Urinary Tract 69 | 16,678
Liver and Pancreas 66 | 16,750
Cardiovascular System 56 | 15,192

Target Family

Non-IDG 45 | 12,091
Transcription Factor 38 | 1,400
Enzyme 9 | 4,145
Kinase 4 | 634
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
GPCR 1 | 408

Jensen-TM Tissue

Primordium 102 | 102
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Deleted in azoospermia protein 1 DAZ1 Tbio Non-IDG -2.24914 176.6 159
Bone morphogenetic protein 15 BMP15 Tbio Non-IDG -2.33917 221.7 200
N-acetyltransferase 9 NAT9 Tdark Enzyme -3.02820 1070.9 44
DNA (cytosine-5)-methyltransferase 3-like DNMT3L Tbio Enzyme -1.95555 87.2 403
Protein boule-like BOLL Tbio Non-IDG -1.87460 71.9 390
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.31332 2140.4 983
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.76391 516.8 355
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Coiled-coil domain-containing protein 8 CCDC8 Tbio Non-IDG -1.06544 12.2 98