Development Level

Tbio 23 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal head morphology 2 | 10
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal skin appearance 1 | 3
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499

Disease

Cancer 22 | 2,499
Osteoporosis 20 | 363
lung cancer 20 | 4,740
Carcinoma 19 | 11,493
ovarian cancer 17 | 8,520
non-small cell lung cancer 14 | 2,890
glioblastoma 13 | 5,792
Ankylosis 12 | 28
Short stature 12 | 531
atypical teratoid / rhabdoid tumor 12 | 5,112
osteosarcoma 12 | 7,950
psoriasis 12 | 6,694
Arthritis 11 | 290
Astrocytoma, Pilocytic 11 | 3,081
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
pancreatic cancer 11 | 2,398
Breast cancer 10 | 3,578
Osteonecrosis 10 | 27
ependymoma 10 | 4,679
Autosomal recessive predisposition 9 | 1,442
Breast Neoplasms 9 | 445
Craniosynostosis 9 | 74
Kidney disease 9 | 430
Mammary Neoplasms 9 | 425
Osteoarthritis 9 | 184
ductal carcinoma in situ 9 | 1,745
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
ulcerative colitis 9 | 1,819
Cleft Palate 8 | 271
Hyperparathyroidism 8 | 48
adult high grade glioma 8 | 3,801
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
Brachydactyly 7 | 156
Cleft Lip 7 | 141
Osteogenesis imperfecta 7 | 34
adrenocortical carcinoma 7 | 1,428
cutaneous lupus erythematosus 7 | 1,057
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
lung carcinoma 7 | 2,843
Congenital deafness 6 | 185
Deafness 6 | 198
Hearing Loss, Partial 6 | 185
Hypercalcemia 6 | 59
Hypotrophic malar bone 6 | 129
Liver Cirrhosis 6 | 181
Liver Cirrhosis, Experimental 6 | 769
Malar flattening 6 | 129
Obesity 6 | 678
Otosclerosis 6 | 15
Prostatic Neoplasms 6 | 495
Uremia 6 | 19
esophageal adenocarcinoma 6 | 737
group 3 medulloblastoma 6 | 4,104
hearing impairment 6 | 199
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
nasopharyngeal carcinoma 6 | 1,058
periodontitis 6 | 293
Ankylosing spondylitis 5 | 140
Atherosclerosis 5 | 291
Big calvaria 5 | 147
Craniofacial Abnormalities 5 | 151
Decreased projection of midface 5 | 105
Fractures, Bone 5 | 13
Hypertension 5 | 396
Hypertensive disease 5 | 292
Hypoplastic mandible condyle 5 | 275
Hypotrophic midface 5 | 105
Increased head circumference 5 | 147
Increased size of cranium 5 | 147
Increased size of skull 5 | 147
Liver disease 5 | 237
Lytic lesion 5 | 32
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Midface retrusion 5 | 105
Neoplasm Metastasis 5 | 168
Orbital separation excessive 5 | 244
Osteolysis 5 | 7
Osteomyelitis 5 | 42
Osteopetrosis 5 | 43
Osteosclerosis 5 | 31
Pulmonary Fibrosis 5 | 106
Rheumatoid arthritis 5 | 1,191
Root resorption 5 | 22
Sensorineural Hearing Loss (disorder) 5 | 284
Small midface 5 | 105
Vascular disease 5 | 319
astrocytic glioma 5 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
tuberculosis 5 | 2,010
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Endocrine System 28 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Digestive Tract 26 | 17,369
Skin and soft tissues 26 | 17,230
Blood and immune system 25 | 16,909
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Urinary Tract 24 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 23 | 12,091
Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634

Jensen-TM Tissue

Preosteoblast 29 | 29
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 SVEP1 Tbio Non-IDG -1.04504 14.5 11
Transcription factor Sp7 SP7 Tbio Transcription Factor -2.81013 605.2 129
Homeobox protein DLX-5 DLX5 Tbio Transcription Factor -2.19455 150.9 405
Fibroblast growth factor 13 FGF13 Tbio Non-IDG -2.94674 831.9 368