Development Level

Tbio 93 | 10,625
Tchem 37 | 1,890
Tclin 25 | 602

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

abnormal behavior 4 | 226
hyperactivity 4 | 108
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
abnormal gait 3 | 51
decreased fasted circulating g... 3 | 49
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased blood urea nitrogen ... 3 | 44
tremors 3 | 34
abnormal epididymis morphology 2 | 31
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
abnormal whole-body plethysmog... 2 | 4
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
enlarged epididymis 2 | 27
enlarged heart 2 | 111
increased body weight 2 | 42
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
limb grasping 2 | 35
straub tail 2 | 26
abnormal anxiety-related respo... 1 | 1
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb morphology 1 | 7
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal outer ear morphology 1 | 1
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal social/conspecific in... 1 | 3
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
convulsive seizures 1 | 11
cyanosis 1 | 6
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body temperature 1 | 2
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating phosphat... 1 | 15
decreased heart rate variabili... 1 | 11
decreased lactate dehydrogenas... 1 | 14
decreased prepulse inhibition 1 | 52
decreased pulmonary respirator... 1 | 4
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
enlarged spleen 1 | 26
hemorrhage 1 | 12
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 92
increased cellular hemoglobin ... 1 | 2
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased startle reflex 1 | 38
increased tidal volume 1 | 1
macrophthalmia 1 | 2
male infertility 1 | 62
mydriasis 1 | 9
short tibia 1 | 82
small testis 1 | 37

Disease

medulloblastoma, large-cell 69 | 6,234
psoriasis 69 | 6,685
glioblastoma 66 | 5,572
ovarian cancer 59 | 8,484
osteosarcoma 53 | 7,933
oligodendroglioma 52 | 2,849
malignant mesothelioma 49 | 3,162
Cancer 48 | 2,346
Neuropathy 48 | 210
lung cancer 48 | 4,466
pilocytic astrocytoma 46 | 3,086
atypical teratoid / rhabdoid tumor 45 | 4,369
subependymal giant cell astrocytoma 37 | 2,287
Carcinoma 36 | 2,147
lung carcinoma 36 | 2,844
pituitary cancer 36 | 1,972
primitive neuroectodermal tumor 35 | 3,031
Epilepsy 34 | 346
pediatric high grade glioma 34 | 2,712
astrocytic glioma 32 | 2,241
Pick disease 31 | 1,893
Neurodegenerative disease 30 | 383
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
Alzheimer's disease 28 | 644
colon cancer 28 | 1,475
group 4 medulloblastoma 28 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,956
invasive ductal carcinoma 28 | 2,950
posterior fossa group A ependymoma 28 | 1,511
cystic fibrosis 27 | 1,665
non-small cell lung cancer 27 | 2,798
diabetes mellitus 26 | 1,663
lung adenocarcinoma 26 | 2,713
ependymoma 25 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
sonic hedgehog group medulloblastoma 25 | 1,482
Schizophrenia 24 | 501
Toxic encephalopathy 24 | 131
Breast cancer 23 | 3,094
interstitial cystitis 23 | 2,299
adult high grade glioma 22 | 2,148
breast carcinoma 22 | 1,614
Parkinson's disease 21 | 364
Cerebrovascular disease 20 | 231
Down syndrome 20 | 548
Hyperalgesia 20 | 71
astrocytoma 20 | 1,493
atypical teratoid/rhabdoid tumor 20 | 1,095
group 3 medulloblastoma 20 | 2,254
pancreatic cancer 19 | 2,300
Pain agnosia 18 | 99
ductal carcinoma in situ 18 | 1,745
ulcerative colitis 18 | 2,087
Amyotrophic Lateral Sclerosis 17 | 431
Multiple Sclerosis 17 | 498
posterior fossa group B ependymoma 17 | 1,530
Intellectual disability 16 | 573
Autistic Disorder 15 | 320
Bipolar Disorder 15 | 266
Obesity 15 | 616
Peripheral Neuropathy 15 | 303
Polyneuropathy 15 | 30
Status Epilepticus 15 | 85
Heart disease 14 | 279
Migraine 14 | 79
Charcot-Marie-Tooth disease 13 | 74
Retinal Degeneration 13 | 49
Seizures 13 | 95
Tonic-clonic epilepsy 13 | 47
Atopic dermatitis 12 | 944
Brain disease 12 | 83
Kidney disease 12 | 396
Vascular disease 12 | 281
acute quadriplegic myopathy 12 | 1,157
tuberculosis 12 | 1,557
Endometriosis 11 | 535
Inflammation 11 | 109
Nerve Degeneration 11 | 73
Rheumatoid Arthritis 11 | 1,160
gastric carcinoma 11 | 832
medulloblastoma 11 | 1,524
Asthma 10 | 349
Cocaine-Related Disorders 10 | 88
Hirschsprung's disease 10 | 42
Hypertension 10 | 287
Arthritis 9 | 248
Blindness 9 | 84
Dementia 9 | 129
Huntington's disease 9 | 72
Inflammatory bowel disease 9 | 142
Local anesthesia 9 | 40
Neuralgia 9 | 16
nervous system disorder 9 | 53
primary pancreatic ductal adenocarcinoma 9 | 1,271
Allergic hypersensitivity disease 8 | 123
adrenocortical carcinoma 8 | 1,427
gastric cancer 8 | 430
inflammatory breast cancer 8 | 404
nephrosclerosis 8 | 329
pancreatic carcinoma 8 | 567

Tissue

Endocrine System 154 | 18,512
Female tissues 154 | 18,647
Nervous System 154 | 18,561
Digestive Tract 153 | 18,473
Urinary Tract 152 | 18,444
Cardiovascular System 149 | 17,958
Liver and Pancreas 149 | 18,136
Skin and soft tissues 148 | 18,115
Blood and immune system 147 | 17,995
Male tissues 145 | 17,969
Respiratory system 143 | 17,484

Target Family

Non-IDG 70 | 11,971
Ion Channel 32 | 341
Enzyme 18 | 4,146
Transcription Factor 18 | 1,400
GPCR 8 | 406
Transporter 5 | 473
Kinase 4 | 634

Jensen-TM Tissue

Peripheral nerve 155 | 155
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Transthyretin TTR Tclin Non-IDG -3.74965 5822.8 617
Recoverin RCVRN Tbio Non-IDG -2.41555 275.7 360