Development Level

Tbio 104 | 11,651
Tclin 28 | 612
Tchem 24 | 1,388
Tdark 1 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 5 | 298
hyperactivity 5 | 148
decreased vertical activity 4 | 208
enlarged heart 4 | 210
increased circulating triglyce... 4 | 42
preweaning lethality, incomple... 4 | 499
abnormal gait 3 | 69
abnormal skin morphology 3 | 50
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased startle reflex 2 | 75
enlarged epididymis 2 | 31
hypoactivity 2 | 132
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
limb grasping 2 | 41
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal adrenal gland morphol... 1 | 1
abnormal anxiety-related respo... 1 | 1
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating iron lev... 1 | 32
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased cellular hemoglobin ... 1 | 1
increased circulating alanine ... 1 | 13
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
macrophthalmia 1 | 2
male infertility 1 | 123
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16

Disease

Carcinoma 111 | 11,493
medulloblastoma, large-cell 72 | 6,241
glioblastoma 70 | 5,792
psoriasis 68 | 6,694
atypical teratoid / rhabdoid tumor 64 | 5,112
ependymoma 59 | 4,679
Schizophrenia 58 | 1,160
ovarian cancer 56 | 8,520
oligodendroglioma 55 | 2,850
osteosarcoma 52 | 7,950
Neuropathy 51 | 261
lung cancer 50 | 4,740
malignant mesothelioma 50 | 3,232
Astrocytoma, Pilocytic 49 | 3,081
Cancer 49 | 2,499
adult high grade glioma 49 | 3,801
group 3 medulloblastoma 45 | 4,104
Epilepsy 44 | 792
astrocytic glioma 41 | 2,597
Bipolar Disorder 40 | 666
Kidney cancer 39 | 2,613
primitive neuroectodermal tumor 39 | 3,035
subependymal giant cell astrocytoma 39 | 2,287
Breast cancer 38 | 3,578
Alzheimer's disease 37 | 658
lung carcinoma 37 | 2,843
pituitary cancer 37 | 1,972
Pick disease 33 | 1,894
Depressive disorder 31 | 409
Neurodegenerative disease 31 | 414
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
Mental Depression 28 | 333
invasive ductal carcinoma 28 | 2,951
Intellectual disability 27 | 1,016
colon cancer 27 | 1,478
cystic fibrosis 27 | 1,696
diabetes mellitus 27 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
non-small cell lung cancer 27 | 2,890
Toxic encephalopathy 26 | 141
lung adenocarcinoma 26 | 2,716
breast carcinoma 25 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
Seizures 24 | 596
Hyperalgesia 23 | 83
group 4 medulloblastoma 23 | 1,855
Cerebrovascular disease 22 | 238
interstitial cystitis 22 | 2,312
Parkinson's disease 21 | 392
Down syndrome 19 | 499
pancreatic cancer 19 | 2,398
Alcoholic Intoxication, Chronic 18 | 289
Autistic Disorder 18 | 364
Autosomal recessive predisposition 18 | 1,442
ductal carcinoma in situ 18 | 1,745
Amyotrophic lateral sclerosis 17 | 451
Major Depressive Disorder 17 | 301
Multiple Sclerosis 17 | 540
Obesity 17 | 678
Pain agnosia 17 | 104
Dull intelligence 16 | 645
Heart disease 16 | 306
Liver cancer 16 | 604
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Peripheral Neuropathy 16 | 134
Poor school performance 16 | 645
tuberculosis 16 | 2,010
Asthma 15 | 385
Hypertension 15 | 396
ulcerative colitis 15 | 1,819
Mood Disorders 14 | 184
Muscle hypotonia 14 | 571
Polyneuropathy 14 | 64
Constipation 13 | 181
Melanoma 13 | 711
Status Epilepticus 13 | 98
Tonic-clonic epilepsy 13 | 47
Unipolar Depression 13 | 250
Vascular disease 13 | 319
astrocytoma 13 | 1,146
Atopic dermatitis 12 | 952
Cognitive delay 12 | 608
Decreased tendon reflex 12 | 122
Global developmental delay 12 | 608
Infantile onset 12 | 238
Kidney disease 12 | 430
Mental and motor retardation 12 | 608
Migraine 12 | 83
Nerve Degeneration 12 | 121
Nystagmus 12 | 317
Retinal Degeneration 12 | 106
Sensorineural Hearing Loss (disorder) 12 | 284
Absent reflex 11 | 92
Cocaine-Related Disorders 11 | 92
Rheumatoid arthritis 11 | 1,191
acute quadriplegic myopathy 11 | 1,158
gastric carcinoma 11 | 807
primary pancreatic ductal adenocarcinoma 11 | 1,109

Tissue

Endocrine System 150 | 18,159
Digestive Tract 144 | 17,369
Female tissues 142 | 17,400
Nervous System 142 | 16,725
Skin and soft tissues 141 | 17,230
Liver and Pancreas 135 | 16,750
Male tissues 135 | 17,142
Blood and immune system 133 | 16,909
Urinary Tract 132 | 16,678
Respiratory system 121 | 16,393
Cardiovascular System 110 | 15,192

Target Family

Non-IDG 73 | 12,091
Ion Channel 32 | 344
Enzyme 17 | 4,145
Transcription Factor 17 | 1,400
GPCR 7 | 408
Transporter 6 | 473
Kinase 5 | 634

Jensen-TM Tissue

Peripheral nerve 157 | 157
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Ciliary neurotrophic factor CNTF Tbio Non-IDG -2.96004 1015.5 485
Transthyretin TTR Tclin Non-IDG -3.79596 6198.3 750
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.50578 2828.7 1992
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -2.00898 110.3 57
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Substance-P receptor TACR1 Tclin GPCR -3.10271 1238.0 435
Rho guanine nucleotide exchange factor 10 ARHGEF10 Tbio Non-IDG -1.93400 86.1 128
AP-1 complex subunit beta-1 AP1B1 Tbio Non-IDG -1.52388 33.5 67
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982