Development Level

Tbio 145 | 11,651
Tchem 62 | 1,388
Tclin 38 | 612
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 16 | 979
preweaning lethality, incomple... 8 | 499
abnormal bone structure 7 | 187
increased total body fat amoun... 7 | 134
embryonic lethality prior to t... 6 | 278
increased startle reflex 6 | 112
abnormal seminal vesicle morph... 5 | 114
decreased lean body mass 5 | 135
decreased vertical activity 5 | 208
enlarged heart 5 | 210
hypoactivity 5 | 132
impaired glucose tolerance 5 | 75
abnormal heart morphology 4 | 162
embryonic lethality prior to o... 4 | 239
increased heart weight 4 | 62
prolonged ST segment 4 | 36
abnormal behavior 3 | 298
abnormal gait 3 | 69
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased grip strength 3 | 116
decreased lymphocyte cell numb... 3 | 83
decreased total body fat amoun... 3 | 207
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
limb grasping 3 | 41
prolonged QT interval 3 | 38
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal lung morphology 2 | 26
abnormal spleen morphology 2 | 55
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased circulating amylase ... 2 | 28
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
enlarged liver 2 | 2
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating chloride... 2 | 41
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
increased neutrophil cell numb... 2 | 46
male infertility 2 | 123
small seminal vesicle 2 | 10
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating chloride... 1 | 30
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Cancer 168 | 2,499
Carcinoma 154 | 11,493
diabetes mellitus 152 | 1,728
psoriasis 111 | 6,694
ovarian cancer 107 | 8,520
lung cancer 97 | 4,740
Obesity 94 | 678
osteosarcoma 90 | 7,950
glioblastoma 88 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 85 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 80 | 2,955
medulloblastoma, large-cell 78 | 6,241
atypical teratoid / rhabdoid tumor 73 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 73 | 2,989
pancreatic cancer 73 | 2,398
Kidney disease 72 | 430
ependymoma 72 | 4,679
malignant mesothelioma 71 | 3,232
Breast cancer 70 | 3,578
Schizophrenia 69 | 1,160
Hypertension 64 | 396
Adenoma 62 | 167
Pancreatitis 62 | 123
Hyperglycemia 60 | 137
adult high grade glioma 60 | 3,801
Astrocytoma, Pilocytic 58 | 3,081
Alzheimer's disease 55 | 658
Heart disease 53 | 306
lung carcinoma 53 | 2,843
oligodendroglioma 53 | 2,850
cystic fibrosis 52 | 1,696
Liver disease 50 | 237
Diarrhea 48 | 253
invasive ductal carcinoma 48 | 2,951
non-small cell lung cancer 48 | 2,890
Arthritis 47 | 290
pituitary cancer 47 | 1,972
Atherosclerosis 45 | 291
Bipolar Disorder 45 | 666
interstitial cystitis 45 | 2,312
lung adenocarcinoma 45 | 2,716
Autosomal recessive predisposition 44 | 1,442
group 3 medulloblastoma 44 | 4,104
primitive neuroectodermal tumor 44 | 3,035
tuberculosis 44 | 2,010
ulcerative colitis 44 | 1,819
Kidney cancer 43 | 2,613
Prostatic Neoplasms 43 | 495
breast carcinoma 43 | 1,638
Vascular disease 41 | 319
Anemia 40 | 365
Breast Neoplasms 40 | 445
Mammary Neoplasms 40 | 425
Stomach Neoplasms 40 | 300
astrocytic glioma 40 | 2,597
Cerebrovascular disease 39 | 238
Diabetes Mellitus, Non-Insulin-Dependent 39 | 145
Asthma 38 | 385
Hypertensive disease 38 | 292
Diabetes Mellitus, Type 2 37 | 142
Hypoglycemia 37 | 152
colon cancer 37 | 1,478
Epilepsy 36 | 792
Liver carcinoma 36 | 240
Carcinoma, Hepatocellular 35 | 228
Coronary artery disease 35 | 268
Lung disease 35 | 142
Major Depressive Disorder 34 | 301
Parkinson's disease 34 | 392
Toxic encephalopathy 34 | 141
Depressive disorder 33 | 409
Rheumatoid arthritis 33 | 1,191
Intellectual disability 32 | 1,016
Lung Neoplasms 32 | 232
Seizures 32 | 596
subependymal giant cell astrocytoma 32 | 2,287
Diabetes Mellitus, Experimental 31 | 108
Hyperinsulinism 31 | 133
Inflammatory bowel disease 31 | 151
Adenocarcinoma 30 | 122
Liver Cirrhosis, Experimental 30 | 769
adrenocortical carcinoma 30 | 1,428
ductal carcinoma in situ 30 | 1,745
Osteoporosis 29 | 363
Alcoholic Intoxication, Chronic 28 | 289
Colonic Neoplasms 28 | 142
Fatty liver disease 28 | 103
Hypersensitivity reaction type II disease 28 | 253
Melanoma 28 | 711
Unipolar Depression 28 | 250
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Inflammation 27 | 120
Multiple Sclerosis 27 | 540
Neoplasm Metastasis 27 | 168
Brain disease 26 | 96
Mental Depression 26 | 333
Neoplasm Invasiveness 26 | 161
Pick disease 26 | 1,894
Low intelligence 25 | 645
Mental Retardation 25 | 645

Tissue

Digestive Tract 235 | 17,369
Endocrine System 233 | 18,159
Liver and Pancreas 225 | 16,750
Female tissues 220 | 17,400
Skin and soft tissues 220 | 17,230
Blood and immune system 210 | 16,909
Male tissues 210 | 17,142
Nervous System 208 | 16,725
Urinary Tract 204 | 16,678
Respiratory system 201 | 16,393
Cardiovascular System 176 | 15,192

Target Family

Non-IDG 109 | 12,091
Enzyme 64 | 4,145
Transcription Factor 35 | 1,400
Kinase 16 | 634
GPCR 14 | 408
Transporter 4 | 473
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 2 | 242

Jensen-TM Tissue

Pancreas 250 | 250
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Pyroglutamyl-peptidase 1 PGPEP1 Tbio Enzyme -2.39412 250.8 91
Calcineurin-binding protein cabin-1 CABIN1 Tbio Non-IDG -3.37173 2194.3 57
Kallikrein-4 KLK4 Tchem Enzyme -3.66176 4527.4 196
Chymotrypsin-C CTRC Tchem Enzyme -2.46349 293.5 81
Resistin RETN Tbio Non-IDG -3.08531 1325.4 684
Pancreatic alpha-amylase AMY2A Tclin Enzyme -2.93089 824.2 250
Potassium channel subfamily K member 16 KCNK16 Tdark Ion Channel -0.94352 8.73 15