Development Level

Tbio 54 | 11,651
Tdark 9 | 6,593
Tchem 3 | 1,388
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased circulating glucose ... 4 | 126
increased circulating alkaline... 4 | 122
abnormal heart morphology 3 | 162
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
cataract 2 | 92
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased eosinophil cell numb... 2 | 24
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
fused cornea and lens 2 | 5
increased total body fat amoun... 2 | 134
iris synechia 2 | 3
narrow eye opening 2 | 12
small superior vagus ganglion 2 | 74
abnormal allantois morphology 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal iris transilluminatio... 1 | 2
abnormal maxilla morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
abnormal zygomatic bone morpho... 1 | 3
anophthalmia 1 | 33
cleft palate 1 | 8
cornea ulcer 1 | 1
cyanosis 1 | 7
decreased B cell number 1 | 5
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened QT interval 1 | 4
vertebral fusion 1 | 23

Disease

Cleft Lip 49 | 141
Cleft Palate 49 | 271
Carcinoma 45 | 11,493
ovarian cancer 31 | 8,520
lung cancer 27 | 4,740
osteosarcoma 26 | 7,950
psoriasis 22 | 6,694
Cancer 20 | 2,499
medulloblastoma, large-cell 20 | 6,241
Breast cancer 19 | 3,578
atypical teratoid / rhabdoid tumor 19 | 5,112
non-small cell lung cancer 18 | 2,890
Uranostaphyloschisis 17 | 167
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
glioblastoma 16 | 5,792
Short stature 15 | 531
ependymoma 15 | 4,679
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
Autosomal recessive predisposition 14 | 1,442
Intellectual disability 14 | 1,016
spina bifida 14 | 1,074
Cognitive delay 13 | 608
Dull intelligence 13 | 645
Global developmental delay 13 | 608
Hypoplastic mandible condyle 13 | 275
Low intelligence 13 | 645
Mandibular hypoplasia 13 | 275
Mental Retardation 13 | 645
Mental and motor retardation 13 | 608
Mental deficiency 13 | 645
Micrognathism 13 | 275
Poor school performance 13 | 645
Tooth agenesis 13 | 44
interstitial cystitis 13 | 2,312
Craniofacial Abnormalities 12 | 151
Epilepsy 12 | 792
ductal carcinoma in situ 12 | 1,745
lung adenocarcinoma 12 | 2,716
Hypotrophic malar bone 11 | 129
Kidney cancer 11 | 2,613
Malar flattening 11 | 129
Orbital separation excessive 11 | 244
Seizures 11 | 596
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
lung carcinoma 11 | 2,843
oligodendroglioma 11 | 2,850
Congenital heart disease 10 | 93
Cryptorchidism 10 | 296
Hypodontia 10 | 81
Polydactyly 10 | 107
adrenocortical carcinoma 10 | 1,428
adult high grade glioma 10 | 3,801
astrocytic glioma 10 | 2,597
Astrocytoma, Pilocytic 9 | 3,081
Choanal Atresia 9 | 42
Decreased projection of maxilla 9 | 66
Deficiency of upper jaw bones 9 | 66
Downward slant of palpebral fissure 9 | 158
Hypoplasia of the maxilla 9 | 66
Hypotrophic maxilla 9 | 66
Maxillary retrognathia 9 | 66
Retrusion of upper jaw bones 9 | 66
Schizophrenia 9 | 1,160
Small head 9 | 374
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Agenesis of corpus callosum 8 | 83
Brachydactyly 8 | 156
Broad flat nasal bridge 8 | 236
Byzanthine arch palate 8 | 194
Decreased size of teeth 8 | 62
Decreased width of tooth 8 | 59
Dental caries 8 | 164
Holoprosencephaly 8 | 56
Low set ears 8 | 181
Microdontia (disorder) 8 | 59
Nasal bridge wide 8 | 236
group 4 medulloblastoma 8 | 1,855
Abnormally small eyeball 7 | 97
Bilateral fifth finger clinodactyly 7 | 110
Bipolar Disorder 7 | 666
Blepharoptosis 7 | 231
Breast Neoplasms 7 | 445
Craniosynostosis 7 | 74
Curvature of little finger 7 | 110
Decreased size of eyeball 7 | 97
Hernia, Inguinal 7 | 89
Hypospadias 7 | 53
Mammary Neoplasms 7 | 425
Microphthalmos 7 | 100
Syndactyly of the toes 7 | 45
Telecanthus 7 | 62
colon cancer 7 | 1,478
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010

Tissue

Endocrine System 68 | 18,159
Digestive Tract 66 | 17,369
Female tissues 63 | 17,400
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Liver and Pancreas 62 | 16,750
Male tissues 62 | 17,142
Urinary Tract 59 | 16,678
Respiratory system 57 | 16,393
Nervous System 56 | 16,725
Cardiovascular System 53 | 15,192

Target Family

Non-IDG 37 | 12,091
Transcription Factor 19 | 1,400
Enzyme 9 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344

Jensen-TM Tissue

Palate 69 | 69
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.53932 4.30 895
T-box transcription factor TBX22 TBX22 Tbio Transcription Factor -2.14590 142.1 138
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697
Nodal homolog NODAL Tbio Non-IDG -3.00545 981.7 245
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.76391 516.8 355
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Orofacial cleft 1 candidate gene 1 protein OFCC1 Tdark Non-IDG -0.32843 2.29 12
DNA-binding protein SATB2 SATB2 Tbio Transcription Factor -2.88608 726.3 200
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448