Development Level

Tbio 11 | 11,445

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal eye anterior chamber ... 1 | 9
abnormal kidney morphology 1 | 65
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
small testis 1 | 58

Disease

Cancer 5 | 2,499
Gonadoblastoma 5 | 34
Hypogonadism 5 | 173
Hypospadias 5 | 53
medulloblastoma, large-cell 5 | 6,241
46 XY gonadal dysgenesis 4 | 10
Azoospermia 4 | 110
Cryptorchidism 4 | 296
Infertility 4 | 188
Male Pseudohermaphroditism 4 | 19
Polycystic ovary syndrome 4 | 360
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Abnormality of male internal genitalia 3 | 4
Amenorrhea 3 | 58
Carcinoma 3 | 11,493
Hypogonadism, Isolated Hypogonadotropic 3 | 71
Hypogonadotropic hypogonadism 3 | 89
Klinefelter's syndrome 3 | 56
Male infertility 3 | 206
Premature ovarian failure 3 | 65
Sclerocystic Ovaries 3 | 17
Swyer Syndrome 3 | 8
Testicular dysgenesis 3 | 9
glioblastoma 3 | 5,792
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
46, XX Testicular Disorders of Sex Development 2 | 3
46,XX ovotesticular disorder of sex development 2 | 2
46,XY partial gonadal dysgenesis 2 | 9
46,Xx Sex Reversal 1 2 | 3
Abnormal scrotal rugation 2 | 2
Abnormal sex determination 2 | 11
Abnormality of the labia 2 | 9
Abnormality of the scrotum 2 | 9
Ambiguous Genitalia 2 | 24
Androgen insensitivity syndrome 2 | 12
Bifid scrotum 2 | 16
Blepharophimosis 2 | 70
Concave bridge of nose 2 | 195
Congenital hypoplasia of penis 2 | 176
Decreased fertility 2 | 33
Decreased fertility in females 2 | 20
Decreased testosterone in males 2 | 28
Delayed Puberty 2 | 97
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dysgerminoma 2 | 11
Elevated follicle stimulating hormone 2 | 15
Elevated gonadotropins 2 | 15
Elevated luteinizing hormone 2 | 14
Female external genitalia in males 2 | 13
Gonadal Dysgenesis 2 | 28
Gonadal Dysgenesis, Mixed 2 | 19
Gynecomastia 2 | 64
Hermaphroditism 2 | 9
Hypertrophy of clitoris 2 | 40
Hypoplasia of scrotum 2 | 24
Hypoplasia of vagina 2 | 14
Low serum estradiol levels 2 | 22
Luteoma 2 | 4
Obesity 2 | 678
Osteoporosis 2 | 363
Ovarian dysfunction 2 | 18
Ovotesticular Disorders of Sex Development 2 | 2
Penile hypospadias 2 | 106
Primary hypogonadism 2 | 37
Primary physiologic amenorrhea 2 | 55
Pseudohermaphroditism 2 | 16
Pure gonadal dysgenesis 2 | 19
Rudimentary vagina 2 | 14
Sex reversal 2 | 10
Short stature 2 | 531
Small testicle 2 | 75
Sparse axillary hair 2 | 28
Sparse pubic hair 2 | 31
Streak ovary 2 | 15
Testicular hypogonadism 2 | 21
Testicular regression syndrome 2 | 9
True Hermaphroditism (disorder) 2 | 4
Urogenital sinus anomaly 2 | 15
Uterine Anomalies 2 | 5
XX males 2 | 3
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
Epicanthus inversus 1 | 3
Glossoptosis 1 | 10
Laryngomalacia 1 | 14
Posterior displacement of the tongue 1 | 10
Respiratory Distress Syndrome 1 | 15

Tissue

Endocrine System 11 | 18,159
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Male tissues 9 | 17,142
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Respiratory system 8 | 16,393
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Liver and Pancreas 7 | 16,750
Urinary Tract 7 | 16,678

Target Family

Transcription Factor 5 | 1,400
Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

Jensen-TM Tissue

Ovotestis 11 | 11
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.43406 2729.3 264
Cyclin-dependent kinase 20 CDK20 Tbio Kinase -1.82269 67.7 248
Ras-related protein Rab-37 RAB37 Tbio Enzyme -0.99553 10.3 241
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Sex-determining region Y protein SRY Tbio Transcription Factor -3.51730 3115.2 198
Protein PAT1 homolog 2 PATL2 Tbio Non-IDG -0.82181 5.89 63
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.81557 652.1 234
Zinc finger Y-chromosomal protein ZFY Tbio Transcription Factor -2.23169 159.0 88
R-spondin-1 RSPO1 Tbio Non-IDG -2.26774 188.7 164