Development Level

Tchem 38 | 1,885
Tbio 25 | 11,178
Tclin 10 | 612
Tdark 1 | 6,569

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal bone mineralization 2 | 38
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent testes 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased large unstained cell... 1 | 11
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
short tibia 1 | 97
small seminal vesicle 1 | 10
small spleen 1 | 19
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Cancer 62 | 2,388
ovarian cancer 56 | 8,297
Carcinoma 53 | 11,192
osteosarcoma 45 | 7,766
glioblastoma 41 | 5,635
psoriasis 37 | 6,514
atypical teratoid / rhabdoid tumor 35 | 4,971
lung cancer 35 | 4,607
Breast cancer 34 | 3,469
medulloblastoma, large-cell 31 | 6,086
ependymoma 30 | 4,559
malignant mesothelioma 29 | 3,135
Breast Neoplasms 28 | 423
Mammary Neoplasms 27 | 403
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,204
Stomach Neoplasms 26 | 287
adult high grade glioma 26 | 3,701
Astrocytoma, Pilocytic 24 | 3,006
Prostatic Neoplasms 24 | 472
invasive ductal carcinoma 24 | 2,867
diabetes mellitus 23 | 1,683
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,902
non-small cell lung cancer 23 | 2,799
pancreatic cancer 23 | 2,322
Vascular disease 22 | 294
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,872
lung adenocarcinoma 22 | 2,627
Neoplasm Metastasis 20 | 160
Schizophrenia 20 | 1,136
group 3 medulloblastoma 20 | 4,002
Kidney disease 19 | 411
Lung Neoplasms 19 | 217
breast carcinoma 19 | 1,589
ductal carcinoma in situ 19 | 1,686
oligodendroglioma 19 | 2,768
Kidney cancer 18 | 2,548
interstitial cystitis 18 | 2,237
primitive neuroectodermal tumor 18 | 2,957
ulcerative colitis 18 | 1,765
Carcinoma, Hepatocellular 17 | 217
Liver carcinoma 17 | 229
Ovarian Neoplasms 17 | 96
adrenocortical carcinoma 17 | 1,385
nasopharyngeal carcinoma 17 | 1,024
ovarian neoplasm 17 | 93
pituitary cancer 17 | 1,915
Heart disease 16 | 288
Neoplasm Invasiveness 16 | 151
Obesity 16 | 655
colon cancer 16 | 1,428
lung carcinoma 16 | 2,755
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,911
Adenocarcinoma 15 | 116
Pancreatic Neoplasms 15 | 82
Squamous cell carcinoma 15 | 125
tuberculosis 15 | 1,963
Adenoma 14 | 159
Cell Transformation, Neoplastic 14 | 90
Pancreatic Neoplasm 14 | 82
Toxic encephalopathy 14 | 139
acute quadriplegic myopathy 14 | 1,133
astrocytic glioma 14 | 2,530
Alzheimer's disease 13 | 640
Asthma 13 | 370
Autosomal recessive predisposition 13 | 1,407
Carcinoma, Squamous Cell 13 | 107
Endometriosis 13 | 521
Neoplastic Cell Transformation 13 | 83
subependymal giant cell astrocytoma 13 | 2,230
Arthritis 12 | 276
Brain Ischemia 12 | 107
Colonic Neoplasms 12 | 133
Disease Progression 12 | 133
Inflammatory bowel disease 12 | 148
Liver disease 12 | 227
Mammary Neoplasms, Experimental 12 | 147
Colorectal Neoplasms 11 | 235
Eye disease 11 | 59
Lung disease 11 | 135
acute myeloid leukemia 11 | 760
hepatocellular carcinoma 11 | 536
non-small cell lung carcinoma 11 | 302
Anemia 10 | 353
Bipolar Disorder 10 | 646
Carcinoma, Non-Small-Cell Lung 10 | 97
Liver Cirrhosis, Experimental 10 | 733
Liver Neoplasms, Experimental 10 | 58
Neurodegenerative disease 10 | 402
Reperfusion Injury 10 | 84
Rheumatoid arthritis 10 | 1,156
Stomach cancer 10 | 30
astrocytoma 10 | 1,113
cystic fibrosis 10 | 1,629
Atopic dermatitis 9 | 915
Depressive disorder 9 | 401
Immune system cancer 9 | 136
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 492
gastric carcinoma 9 | 781
juvenile dermatomyositis 9 | 1,147
primary pancreatic ductal adenocarcinoma 9 | 1,071

Tissue

Digestive Tract 73 | 17,369
Endocrine System 73 | 18,159
Skin and soft tissues 73 | 17,230
Blood and immune system 72 | 16,909
Female tissues 72 | 17,400
Liver and Pancreas 72 | 16,750
Male tissues 72 | 17,142
Respiratory system 72 | 16,393
Urinary Tract 72 | 16,678
Cardiovascular System 71 | 15,192
Nervous System 71 | 16,725

Target Family

Non-IDG 29 | 12,091
Enzyme 15 | 4,145
Kinase 15 | 634
Transcription Factor 9 | 1,400
GPCR 3 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

Jensen-TM Tissue

Ovary cancer cell 74 | 74
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Lysophosphatidic acid receptor 3 LPAR3 Tchem GPCR -2.11449 131.9 238
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Mucin-16 MUC16 Tchem Non-IDG -2.09951 138.4 0
Nucleolar MIF4G domain-containing protein 1 NOM1 Tdark Non-IDG -1.32809 20.1 38
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Claudin-3 CLDN3 Tbio Non-IDG -2.37681 227.3 358
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833