Development Level

Tchem 33 | 1,388
Tbio 30 | 11,651
Tclin 10 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal bone mineralization 2 | 38
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent testes 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased large unstained cell... 1 | 11
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
short tibia 1 | 97
small seminal vesicle 1 | 10
small spleen 1 | 19
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Cancer 66 | 2,499
ovarian cancer 58 | 8,520
Carcinoma 57 | 11,493
osteosarcoma 48 | 7,950
glioblastoma 45 | 5,792
psoriasis 40 | 6,694
atypical teratoid / rhabdoid tumor 38 | 5,112
lung cancer 38 | 4,740
Breast cancer 36 | 3,578
malignant mesothelioma 33 | 3,232
Breast Neoplasms 32 | 445
ependymoma 32 | 4,679
medulloblastoma, large-cell 32 | 6,241
Mammary Neoplasms 31 | 425
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
adult high grade glioma 27 | 3,801
Astrocytoma, Pilocytic 26 | 3,081
Prostatic Neoplasms 26 | 495
Stomach Neoplasms 26 | 300
non-small cell lung cancer 26 | 2,890
pancreatic cancer 26 | 2,398
diabetes mellitus 25 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
invasive ductal carcinoma 25 | 2,951
lung adenocarcinoma 25 | 2,716
Vascular disease 24 | 319
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
Neoplasm Metastasis 22 | 168
Schizophrenia 22 | 1,160
Kidney cancer 21 | 2,613
Kidney disease 21 | 430
breast carcinoma 21 | 1,638
ductal carcinoma in situ 21 | 1,745
group 3 medulloblastoma 21 | 4,104
oligodendroglioma 20 | 2,850
primitive neuroectodermal tumor 20 | 3,035
ulcerative colitis 20 | 1,819
Carcinoma, Hepatocellular 19 | 228
Liver carcinoma 19 | 240
Lung Neoplasms 19 | 232
Neoplasm Invasiveness 19 | 161
interstitial cystitis 19 | 2,312
nasopharyngeal carcinoma 19 | 1,058
Heart disease 18 | 306
Ovarian Neoplasms 18 | 102
adrenocortical carcinoma 18 | 1,428
colon cancer 18 | 1,478
lung carcinoma 18 | 2,843
ovarian neoplasm 18 | 99
Cell Transformation, Neoplastic 17 | 97
Obesity 17 | 678
Pancreatic Neoplasms 17 | 85
pituitary cancer 17 | 1,972
Adenocarcinoma 16 | 122
Neoplastic Cell Transformation 16 | 89
Pancreatic Neoplasm 16 | 85
Squamous cell carcinoma 16 | 129
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
tuberculosis 16 | 2,010
Arthritis 15 | 290
Autosomal recessive predisposition 15 | 1,442
Endometriosis 15 | 540
astrocytic glioma 15 | 2,597
Adenoma 14 | 167
Alzheimer's disease 14 | 658
Asthma 14 | 385
Carcinoma, Squamous Cell 14 | 110
Liver disease 14 | 237
Mammary Neoplasms, Experimental 14 | 154
Toxic encephalopathy 14 | 141
acute quadriplegic myopathy 14 | 1,158
subependymal giant cell astrocytoma 14 | 2,287
Brain Ischemia 13 | 110
Colonic Neoplasms 13 | 142
Disease Progression 13 | 136
Eye disease 13 | 62
Inflammatory bowel disease 13 | 151
cystic fibrosis 13 | 1,696
Colorectal Neoplasms 12 | 243
Liver Cirrhosis, Experimental 12 | 769
Lung disease 12 | 142
non-small cell lung carcinoma 12 | 317
primary pancreatic ductal adenocarcinoma 12 | 1,109
Anemia 11 | 365
Bipolar Disorder 11 | 666
Carcinoma, Non-Small-Cell Lung 11 | 107
Hypertension 11 | 396
Reperfusion Injury 11 | 86
Rheumatoid arthritis 11 | 1,191
acute myeloid leukemia 11 | 783
astrocytoma 11 | 1,146
hepatocellular carcinoma 11 | 547
Atherosclerosis 10 | 291
Atopic dermatitis 10 | 952
Depressive disorder 10 | 409
Esophageal Neoplasms 10 | 69
Liver Neoplasms, Experimental 10 | 59
Neurodegenerative disease 10 | 414
Stomach cancer 10 | 30
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510

Tissue

Digestive Tract 73 | 17,369
Endocrine System 73 | 18,159
Skin and soft tissues 73 | 17,230
Blood and immune system 72 | 16,909
Female tissues 72 | 17,400
Liver and Pancreas 72 | 16,750
Male tissues 72 | 17,142
Respiratory system 72 | 16,393
Urinary Tract 72 | 16,678
Cardiovascular System 71 | 15,192
Nervous System 71 | 16,725

Target Family

Non-IDG 29 | 12,091
Enzyme 15 | 4,145
Kinase 15 | 634
Transcription Factor 9 | 1,400
GPCR 3 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

Jensen-TM Tissue

Ovary cancer cell 74 | 74
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Twinkle protein, mitochondrial TWNK Tbio Non-IDG -2.18726 156.1 146
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809