Development Level

Tbio 168 | 11,178
Tchem 119 | 1,885
Tclin 64 | 612
Tdark 2 | 6,569

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 24 | 979
preweaning lethality, incomple... 15 | 499
embryonic lethality prior to t... 13 | 278
embryonic lethality prior to o... 11 | 239
abnormal behavior 10 | 298
increased total body fat amoun... 10 | 134
decreased bone mineral content 9 | 151
abnormal embryo size 8 | 220
enlarged heart 8 | 210
small testis 8 | 58
increased circulating choleste... 7 | 66
abnormal seminal vesicle morph... 6 | 114
decreased lean body mass 6 | 135
increased circulating HDL chol... 6 | 80
abnormal heart morphology 5 | 162
abnormal retina morphology 5 | 71
abnormal testis morphology 5 | 43
decreased total body fat amoun... 5 | 207
hypoactivity 5 | 132
increased circulating alkaline... 5 | 122
male infertility 5 | 123
small superior vagus ganglion 5 | 74
abnormal bone structure 4 | 187
cataract 4 | 92
decreased bone mineral density 4 | 126
decreased circulating insulin ... 4 | 76
decreased heart weight 4 | 27
decreased lymphocyte cell numb... 4 | 83
decreased vertical activity 4 | 208
female infertility 4 | 60
improved glucose tolerance 4 | 79
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
thrombocytopenia 4 | 56
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
abnormal lung morphology 3 | 26
abnormal midbrain development 3 | 20
abnormal neural tube closure 3 | 46
abnormal sleep behavior 3 | 70
decreased circulating HDL chol... 3 | 68
decreased circulating calcium ... 3 | 36
decreased erythrocyte cell num... 3 | 62
decreased leukocyte cell numbe... 3 | 73
decreased spleen weight 3 | 10
hydrometra 3 | 53
increased bone mineral content 3 | 108
increased circulating iron lev... 3 | 30
increased circulating serum al... 3 | 22
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
increased startle reflex 3 | 112
microphthalmia 3 | 26
small seminal vesicle 3 | 10
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal hindbrain development 2 | 16
abnormal vibrissa morphology 2 | 25
absent testes 2 | 6
decreased body length 2 | 101
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
embryonic growth retardation 2 | 106
enlarged heart atrium 2 | 4
enlarged spleen 2 | 41
enlarged uterus 2 | 11
hyperactivity 2 | 148
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating bilirubi... 2 | 16
increased circulating potassiu... 2 | 29
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased mean platelet volume 2 | 45
limb grasping 2 | 41
pale yolk sac 2 | 25
pallor 2 | 34
premature death 2 | 5
prolonged QT interval 2 | 38
short tibia 2 | 97
small kidney 2 | 16
tremors 2 | 39

Disease

Cancer 229 | 2,388
Carcinoma 223 | 11,192
ovarian cancer 181 | 8,297
psoriasis 169 | 6,514
osteosarcoma 149 | 7,766
lung cancer 132 | 4,607
glioblastoma 127 | 5,635
medulloblastoma, large-cell 123 | 6,086
diabetes mellitus 119 | 1,683
Breast cancer 111 | 3,469
malignant mesothelioma 106 | 3,135
atypical teratoid / rhabdoid tumor 100 | 4,971
ependymoma 95 | 4,559
Schizophrenia 87 | 1,136
intraductal papillary-mucinous neoplasm (IPMN) 84 | 3,204
Autosomal recessive predisposition 82 | 1,407
invasive ductal carcinoma 82 | 2,867
Astrocytoma, Pilocytic 77 | 3,006
Kidney cancer 77 | 2,548
Hypertension 76 | 372
group 3 medulloblastoma 76 | 4,002
lung adenocarcinoma 76 | 2,627
intraductal papillary-mucinous adenoma (IPMA) 75 | 2,872
Obesity 73 | 655
pancreatic cancer 73 | 2,322
Kidney disease 71 | 411
adult high grade glioma 71 | 3,701
lung carcinoma 71 | 2,755
ulcerative colitis 71 | 1,765
interstitial cystitis 70 | 2,237
Breast Neoplasms 69 | 423
Mammary Neoplasms 68 | 403
Prostatic Neoplasms 68 | 472
breast carcinoma 68 | 1,589
non-small cell lung cancer 67 | 2,799
pituitary cancer 65 | 1,915
Heart disease 64 | 288
Infertility 63 | 176
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,902
cystic fibrosis 62 | 1,629
tuberculosis 61 | 1,963
ductal carcinoma in situ 59 | 1,686
oligodendroglioma 59 | 2,768
primitive neuroectodermal tumor 59 | 2,957
colon cancer 57 | 1,428
Alzheimer's disease 56 | 640
Stomach Neoplasms 55 | 287
Adenoma 54 | 159
Vascular disease 53 | 294
adrenocortical carcinoma 53 | 1,385
Endometriosis 52 | 521
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,911
Anemia 50 | 353
subependymal giant cell astrocytoma 50 | 2,230
Atherosclerosis 49 | 276
Cerebrovascular disease 49 | 223
Depressive disorder 49 | 401
Polycystic ovary syndrome 49 | 348
astrocytic glioma 49 | 2,530
Asthma 48 | 370
Liver Cirrhosis, Experimental 48 | 733
Liver disease 48 | 227
Rheumatoid arthritis 48 | 1,156
Bipolar Disorder 47 | 646
Carcinoma, Hepatocellular 47 | 217
Coronary artery disease 47 | 253
Liver carcinoma 47 | 229
Arthritis 45 | 276
Epilepsy 45 | 775
Hypertensive disease 44 | 278
Lung Neoplasms 44 | 217
group 4 medulloblastoma 43 | 1,806
Major Depressive Disorder 42 | 293
Seizures 42 | 584
nasopharyngeal carcinoma 42 | 1,024
Melanoma 41 | 689
Multiple Sclerosis 41 | 527
Osteoporosis 41 | 348
Neoplasm Metastasis 40 | 160
Short stature 40 | 514
Toxic encephalopathy 40 | 139
Intellectual disability 38 | 998
acute quadriplegic myopathy 38 | 1,133
Cryptorchidism 37 | 287
Hyperglycemia 37 | 134
Pick disease 37 | 1,856
Adenocarcinoma 36 | 116
Colorectal Neoplasms 36 | 235
Diarrhea 36 | 245
Mental Depression 36 | 325
Multiple myeloma 36 | 1,296
Unipolar Depression 36 | 244
Lung disease 35 | 135
Neurodegenerative disease 35 | 402
cutaneous lupus erythematosus 35 | 1,016
Cognitive delay 34 | 596
Global developmental delay 34 | 596
Mental and motor retardation 34 | 596
Thrombocytopenia 34 | 193
astrocytoma 34 | 1,113

Tissue

Endocrine System 340 | 18,159
Digestive Tract 332 | 17,369
Female tissues 331 | 17,400
Skin and soft tissues 326 | 17,230
Male tissues 325 | 17,142
Blood and immune system 323 | 16,909
Liver and Pancreas 318 | 16,750
Nervous System 311 | 16,725
Respiratory system 311 | 16,393
Urinary Tract 310 | 16,678
Cardiovascular System 281 | 15,192

Target Family

Non-IDG 178 | 12,091
Enzyme 72 | 4,145
Transcription Factor 31 | 1,400
Kinase 30 | 634
GPCR 17 | 408
Ion Channel 9 | 344
Nuclear Receptor 8 | 48
Transporter 6 | 473
Epigenetic 2 | 242

Jensen-TM Tissue

Ovary 353 | 353
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.19109 1432.9 1169
Homeobox protein NANOG NANOG Tchem Transcription Factor -2.94914 1130.5 958
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
Beta-2 adrenergic receptor ADRB2 Tclin GPCR -3.22695 1680.9 829
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151
TFIIH basal transcription factor complex helicase XPD subunit ERCC2 Tbio Enzyme -2.58326 365.8 191