Targets

Target Filters...

This is where graphics are reside..

Name	Gene	Development Level	Target Family	Log Novelty	Pubmed Score	Antibody Count
Unconventional myosin-VIIa	MYO7A	Tbio	Non-IDG	-2.10835	131.7	114
Pejvakin	DFNB59	Tbio	Non-IDG	-1.14340	15.5	51
Protocadherin-15	PCDH15	Tchem	Non-IDG	-1.81368	69.7	32
Unconventional myosin-XV	MYO15A	Tbio	Non-IDG	-1.61584	50.5	13
Harmonin	USH1C	Tbio	Non-IDG	-2.07484	115.8	173
CUE domain-containing protein 1	CUEDC1	Tdark	Non-IDG	-0.34242	2.17	69
Calbindin	CALB1	Tbio	Non-IDG	-3.30395	2070.6	233
Choline O-acetyltransferase	CHAT	Tchem	Enzyme	-3.39347	2550.6	355
Putative stereocilin-like protein	STRCP1	Tdark	Non-IDG	-1.27085	35.9	0
Splicing factor, suppressor of white-apricot homolog	SFSWAP	Tdark	Non-IDG	-0.39794	2.82	138

	Tbio	23 \| 10,625
	Tdark	10 \| 7,003
	Tchem	3 \| 1,890
	Tclin	2 \| 602

	increased or absent threshold ...	6 \| 128
	absent pinna reflex	3 \| 21
	decreased circulating HDL chol...	3 \| 77
	decreased circulating amylase ...	3 \| 24
	decreased circulating choleste...	3 \| 85
	decreased circulating triglyce...	3 \| 83
	decreased grip strength	3 \| 123
	decreased prepulse inhibition	3 \| 52
	increased circulating chloride...	3 \| 43
	increased circulating sodium l...	3 \| 71
	trunk curl	3 \| 15
	abnormal behavior	2 \| 226
	abnormal bone structure	2 \| 131
	abnormal locomotor activation	2 \| 26
	absent startle reflex	2 \| 15
	decreased body length	2 \| 108
	decreased body weight	2 \| 174
	decreased circulating free fat...	2 \| 39
	decreased circulating glucose ...	2 \| 121
	decreased lean body mass	2 \| 195
	decreased startle reflex	2 \| 48
	decreased total body fat amoun...	2 \| 186
	hyperactivity	2 \| 108
	impaired righting response	2 \| 19
	increased blood urea nitrogen ...	2 \| 44
	increased circulating alkaline...	2 \| 119
	increased lean body mass	2 \| 107
	stereotypic behavior	2 \| 3
	abnormal bone mineralization	1 \| 55
	abnormal coping response	1 \| 12
	abnormal ear morphology	1 \| 5
	abnormal epididymis morphology	1 \| 31
	abnormal gait	1 \| 51
	abnormal glucose homeostasis	1 \| 5
	abnormal motor coordination/ b...	1 \| 4
	abnormal respiratory quotient	1 \| 9
	abnormal response to tactile s...	1 \| 16
	abnormal skin morphology	1 \| 23
	abnormal startle reflex	1 \| 14
	circling	1 \| 1
	decreased B cell number	1 \| 30
	decreased bone mineral content	1 \| 157
	decreased bone mineral density	1 \| 126
	decreased circulating glycerol...	1 \| 19
	decreased circulating insulin ...	1 \| 75
	decreased circulating potassiu...	1 \| 17
	decreased hemoglobin content	1 \| 53
	decreased leukocyte cell numbe...	1 \| 54
	decreased spleen weight	1 \| 13
	enlarged epididymis	1 \| 27
	head bobbing	1 \| 3
	impaired pupillary reflex	1 \| 14
	improved glucose tolerance	1 \| 56
	increased NK T cell number	1 \| 11
	increased bone mineral content	1 \| 92
	increased hemoglobin content	1 \| 45
	increased mean corpuscular hem...	1 \| 93
	increased mean corpuscular vol...	1 \| 91
	increased mean platelet volume	1 \| 19
	increased rib number	1 \| 41
	increased thermal nociceptive ...	1 \| 9
	limb grasping	1 \| 35
	persistence of hyaloid vascula...	1 \| 22
	sclerocornea	1 \| 2
	short tibia	1 \| 82
	straub tail	1 \| 26
	thrombocytopenia	1 \| 46
	tremors	1 \| 34

	Nonsyndromic deafness	23 \| 121
	psoriasis	19 \| 6,685
	Sensorineural hearing loss	18 \| 107
	osteosarcoma	16 \| 7,933
	glioblastoma	15 \| 5,572
	medulloblastoma, large-cell	15 \| 6,234
	atypical teratoid / rhabdoid tumor	12 \| 4,369
	ovarian cancer	12 \| 8,492
	pilocytic astrocytoma	11 \| 3,086
	primitive neuroectodermal tumor	11 \| 3,031
	Hodgkin's lymphoma, nodular sclerosis	10 \| 24
	Pick disease	10 \| 1,893
	pediatric high grade glioma	10 \| 2,712
	lung carcinoma	9 \| 2,844
	oligodendroglioma	9 \| 2,849
	pituitary cancer	9 \| 1,972
	sonic hedgehog group medulloblastoma	9 \| 1,482
	adult high grade glioma	7 \| 2,148
	astrocytic glioma	7 \| 2,241
	ependymoma	7 \| 2,514
	subependymal giant cell astrocytoma	7 \| 2,287
	Carcinoma	6 \| 2,147
	Retinitis pigmentosa	6 \| 156
	Usher syndrome	6 \| 34
	interstitial cystitis	6 \| 2,299
	lung adenocarcinoma	6 \| 2,714
	lung cancer	6 \| 4,473
	malignant mesothelioma	6 \| 3,163
	ulcerative colitis	6 \| 2,087
	Blindness	5 \| 84
	Toxic encephalopathy	5 \| 131
	adrenocortical carcinoma	5 \| 1,427
	astrocytoma	5 \| 1,493
	cystic fibrosis	5 \| 1,670
	intraductal papillary-mucinous adenoma (IPMA)	5 \| 2,956
	medulloblastoma	5 \| 1,524
	pancreatic cancer	5 \| 2,300
	posterior fossa group A ependymoma	5 \| 1,511
	Alzheimer's disease	4 \| 644
	Breast cancer	4 \| 3,099
	Cancer	4 \| 2,346
	Epilepsy	4 \| 346
	Usher Syndrome, Type 1	4 \| 7
	acute quadriplegic myopathy	4 \| 1,157
	atypical teratoid/rhabdoid tumor	4 \| 1,095
	invasive ductal carcinoma	4 \| 2,950
	non-small cell lung cancer	4 \| 2,798
	non-small cell lung carcinoma	4 \| 413
	posterior fossa group B ependymoma	4 \| 1,530
	tuberculosis	4 \| 1,563
	Cerebrovascular disease	3 \| 231
	Deafness	3 \| 18
	Endometriosis	3 \| 535
	Heart disease	3 \| 279
	Hypertension	3 \| 293
	Long QT syndrome	3 \| 53
	Multiple Sclerosis	3 \| 498
	Neuropathy	3 \| 210
	Parkinson's disease	3 \| 364
	Rheumatoid Arthritis	3 \| 1,171
	Schizophrenia	3 \| 503
	chronic rhinosinusitis	3 \| 512
	diabetes mellitus	3 \| 1,663
	group 3 medulloblastoma	3 \| 2,254
	hepatocellular carcinoma	3 \| 550
	intraductal papillary-mucinous carcinoma (IPMC)	3 \| 2,988
	intraductal papillary-mucinous neoplasm (IPMN)	3 \| 3,289
	pancreatic carcinoma	3 \| 567
	Amyotrophic Lateral Sclerosis	2 \| 432
	Atopic dermatitis	2 \| 944
	Brain disease	2 \| 84
	Dementia	2 \| 129
	Diastrophic dysplasia	2 \| 21
	Endolymphatic hydrops	2 \| 3
	Epidermodysplasia verruciformis	2 \| 21
	Eye disease	2 \| 55
	Gaucher disease type 1	2 \| 171
	Hypothyroidism	2 \| 89
	Male infertility	2 \| 170
	Malignant hyperthermia	2 \| 25
	Metabolic acidosis	2 \| 49
	Neurodegenerative disease	2 \| 383
	Obesity	2 \| 616
	Prostatic Neoplasms	2 \| 471
	Pseudoachondroplasia	2 \| 11
	Tetanus	2 \| 66
	USHER SYNDROME, TYPE ID	2 \| 2
	Usher Syndrome, Type II	2 \| 4
	Usher syndrome 1D/F	2 \| 2
	Usher syndrome type 1D	2 \| 2
	Usher syndrome type 2	2 \| 5
	Usher syndrome, type 1D	2 \| 2
	aldosterone-producing adenoma	2 \| 664
	colon cancer	2 \| 1,475
	cutaneous lupus erythematosus	2 \| 1,056
	gastric cancer	2 \| 436
	hearing impairment	2 \| 40
	nasopharyngeal carcinoma	2 \| 1,056
	spina bifida	2 \| 1,064
	urothelial carcinoma	2 \| 318

	Digestive Tract	37 \| 18,473
	Endocrine System	37 \| 18,512
	Female tissues	37 \| 18,647
	Liver and Pancreas	37 \| 18,136
	Nervous System	37 \| 18,561
	Skin and soft tissues	37 \| 18,115
	Urinary Tract	37 \| 18,444
	Blood and immune system	36 \| 17,995
	Cardiovascular System	36 \| 17,958
	Male tissues	35 \| 17,969
	Respiratory system	34 \| 17,484

	Non-IDG	23 \| 11,969
	Ion Channel	5 \| 341
	Transporter	5 \| 473
	Enzyme	3 \| 4,146
	Transcription Factor	2 \| 1,400

Development Level

Collection

IMPC Term

Disease

Tissue

Target Family

Jensen-TM Tissue

Drug Target Ontology

Target Development Level

Target Family

PANTHER Protein Ontology

Ligand

GTEx Tissue

HPA RNA Tissue

HPA Protein Tissue

HPM Tissue

JAX/MGI Phenotype

OMIM Phenotype

GWAS Trait

GO Component

UniProt Keywords

Grant Funding IC

Grant Activity

Data Source

	Outer hair cell	38 \| 38
	Blood	1,867 \| 1,867
	Brain	1,442 \| 1,442
	Immune system	1,150 \| 1,150
	Muscle	1,110 \| 1,110
	Liver	1,001 \| 1,001
	Adult	976 \| 976
	Heart	881 \| 881
	Kidney	840 \| 840
	Neuron	744 \| 744
	Skin	735 \| 735
	Intestine	626 \| 626
	Lung	623 \| 623
	Spinal cord	526 \| 526
	Bone marrow	494 \| 494
	Finger	432 \| 432
	Breast	429 \| 429
	Blood vessel	387 \| 387
	Hematopoietic stem cell	370 \| 370
	Ovary	342 \| 342
	Artery	327 \| 327
	Ganglion	322 \| 322
	Retina	301 \| 301
	Nerve	290 \| 290
	Urine	281 \| 281
	Semen	266 \| 266
	Fiber	263 \| 263
	Mesenchyme	261 \| 261
	Germ cell	244 \| 244
	BTO:0000964	243 \| 243
	Pancreas	239 \| 239
	Breast cancer cell line	228 \| 228
	Trophoblast	225 \| 225
	Breast cancer cell	222 \| 222
	Embryonic stem cell	218 \| 218
	Adrenal gland	207 \| 207
	Lymph node	206 \| 206
	Adipocyte	194 \| 194
	Thyroid gland	190 \| 190
	Cornea	186 \| 186
	Stromal cell	183 \| 183
	Stomach	179 \| 179
	Osteoblast	175 \| 175
	Marrow	169 \| 169
	Blood plasma	165 \| 165
	Mesenchymal stem cell	159 \| 159
	T-lymphocyte	158 \| 158
	Mast cell	155 \| 155
	Peripheral nerve	155 \| 155
	Cranium	141 \| 141
	Ectoderm	141 \| 141
	Filament	139 \| 139
	Root nodule	135 \| 135
	Spermatid	135 \| 135
	Neural crest	134 \| 134
	Spleen	130 \| 130
	Uterine cervix	124 \| 124
	Blood vessel endothelium	122 \| 122
	Prostate cancer cell line	121 \| 121
	Prostate gland cancer cell	121 \| 121
	HeLa cell	120 \| 120
	Neural tube	120 \| 120
	Vasculature	119 \| 119
	Blastocyst	117 \| 117
	HUVEC cell	116 \| 116
	Hepatoma cell	113 \| 113
	Fruit	112 \| 112
	Knee	112 \| 112
	Neural stem cell	112 \| 112
	NIH-3T3 cell	109 \| 109
	Seedling	109 \| 109
	Tendon	108 \| 108
	Lung cancer cell	107 \| 107
	Hip	106 \| 106
	Bronchoalveolar lavage	105 \| 105
	Primordium	104 \| 104
	Bud	103 \| 103
	Capillary	101 \| 101
	Myotube	101 \| 101
	B-lymphocyte	99 \| 99
	Myoblast	99 \| 99
	Colonic cancer cell	98 \| 98
	Peripheral blood	96 \| 96
	Vegetative cell	96 \| 96
	Germ	95 \| 95
	Somatic cell	92 \| 92
	Endoderm	91 \| 91
	Embryonic fibroblast	90 \| 90
	Salivary gland	90 \| 90
	3T3-L1 cell	88 \| 88
	Epididymis	88 \| 88
	Neonate	88 \| 88
	Mesoderm	87 \| 87
	Vagina	87 \| 87
	Hair cell	86 \| 86
	Ascites	85 \| 85
	Parenchyma	85 \| 85
	Saliva	84 \| 84
	Synovial tissue	83 \| 83
	Carcass	82 \| 82
	Spike	80 \| 80