Development Level

Tbio 32 | 11,445
Tchem 9 | 1,598
Tclin 4 | 613

IMPC Phenotype

decreased circulating calcium ... 4 | 36
abnormal bone structure 3 | 187
abnormal tibia morphology 3 | 14
decreased body length 3 | 101
decreased bone mineral content 3 | 151
abnormal bone mineralization 2 | 38
abnormal cranium morphology 2 | 36
abnormal femur morphology 2 | 14
abnormal head morphology 2 | 10
abnormal humerus morphology 2 | 11
abnormal joint morphology 2 | 23
abnormal radius morphology 2 | 8
abnormal seminal vesicle morph... 2 | 114
abnormal ulna morphology 2 | 8
abnormal vertebrae morphology 2 | 18
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating phosphat... 2 | 27
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal fibula morphology 1 | 2
abnormal incisor color 1 | 3
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
absent mammary gland 1 | 1
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased startle reflex 1 | 112
long tail 1 | 1
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thick tail 1 | 1
thin skin 1 | 2

Disease

Cancer 35 | 2,499
Carcinoma 32 | 11,493
Osteoporosis 30 | 363
glioblastoma 26 | 5,792
ovarian cancer 24 | 8,520
invasive ductal carcinoma 22 | 2,951
lung cancer 22 | 4,740
psoriasis 21 | 6,694
pancreatic cancer 20 | 2,398
Arthritis 19 | 290
Astrocytoma, Pilocytic 19 | 3,081
Autosomal recessive predisposition 19 | 1,442
Short stature 19 | 531
diabetes mellitus 19 | 1,728
osteosarcoma 19 | 7,950
Breast cancer 18 | 3,578
non-small cell lung cancer 18 | 2,890
Hyperparathyroidism 17 | 48
Rickets 17 | 49
Hypophosphatemia 16 | 40
ependymoma 16 | 4,679
ulcerative colitis 16 | 1,819
Kidney disease 15 | 430
Osteomalacia 15 | 35
adult high grade glioma 15 | 3,801
ductal carcinoma in situ 15 | 1,745
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung adenocarcinoma 15 | 2,716
medulloblastoma, large-cell 15 | 6,241
Hypercalcemia 14 | 59
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
Osteosclerosis 13 | 31
cystic fibrosis 13 | 1,696
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Bone pain 12 | 42
Calcinosis 12 | 70
pituitary cancer 12 | 1,972
Hyperphosphatemia 11 | 32
Hypertension 11 | 396
Osteoarthritis 11 | 184
Osteonecrosis 11 | 27
primitive neuroectodermal tumor 11 | 3,035
tuberculosis 11 | 2,010
Ankylosis 10 | 28
Duchenne muscular dystrophy 10 | 601
Osteogenesis imperfecta 10 | 34
Root resorption 10 | 22
adrenocortical carcinoma 10 | 1,428
group 3 medulloblastoma 10 | 4,104
primary pancreatic ductal adenocarcinoma 10 | 1,109
Craniosynostosis 9 | 74
Frequent fractures 9 | 53
Hyperostosis 9 | 18
Increased fracture rate 9 | 53
Late tooth eruption 9 | 61
Liver Cirrhosis, Experimental 9 | 769
Lytic lesion 9 | 32
Prostatic Neoplasms 9 | 495
Varying degree of multiple fractures 9 | 53
cutaneous lupus erythematosus 9 | 1,057
esophageal adenocarcinoma 9 | 737
oligodendroglioma 9 | 2,850
periodontitis 9 | 293
Adenoma 8 | 167
Alkaline phosphatase serum increased 8 | 29
Atherosclerosis 8 | 291
Breast Neoplasms 8 | 445
Frontal bossing 8 | 157
Hypersensitivity reaction type II disease 8 | 253
Hypertensive disease 8 | 292
Kidney cancer 8 | 2,613
Mammary Neoplasms 8 | 425
Obesity 8 | 678
Osteopetrosis 8 | 43
Uremia 8 | 19
astrocytic glioma 8 | 2,597
gastric carcinoma 8 | 807
juvenile dermatomyositis 8 | 1,187
nasopharyngeal carcinoma 8 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Anemia 7 | 365
Atopic dermatitis 7 | 952
Down syndrome 7 | 499
Endometriosis 7 | 540
Heart disease 7 | 306
Hypoparathyroidism 7 | 41
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Osteochondrodysplasias 7 | 72
Rheumatoid arthritis 7 | 1,191
Vascular disease 7 | 319
active Crohn's disease 7 | 922
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
subependymal giant cell astrocytoma 7 | 2,287

Tissue

Endocrine System 42 | 18,159
Digestive Tract 41 | 17,369
Blood and immune system 40 | 16,909
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Skin and soft tissues 40 | 17,230
Urinary Tract 39 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 11 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Osteocyte 45 | 45
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Transcription factor Sp7 SP7 Tbio Transcription Factor -2.81013 605.2 129
Extracellular serine/threonine protein kinase FAM20C FAM20C Tbio Enzyme -2.32591 210.3 90
Fibroblast growth factor 23 FGF23 Tbio Non-IDG -3.19500 1726.4 296