Development Level

Tbio 10 | 11,445

IMPC Phenotype

abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased total body fat amoun... 1 | 207
increased blood urea nitrogen ... 1 | 48
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
ependymoma 8 | 4,679
glioblastoma 7 | 5,792
invasive ductal carcinoma 7 | 2,951
atypical teratoid / rhabdoid tumor 6 | 5,112
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
adult high grade glioma 5 | 3,801
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
primary pancreatic ductal adenocarcinoma 5 | 1,109
Glaucoma 4 | 239
Joint stiffness 4 | 84
Kidney cancer 4 | 2,613
Weill-Marchesani syndrome 4 | 14
astrocytic glioma 4 | 2,597
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Aortic Valve Insufficiency 3 | 40
Aortic aneurysm 3 | 38
Congenital pectus carinatum 3 | 52
Duchenne muscular dystrophy 3 | 601
Ectopia Lentis 3 | 17
Hypertensive disease 3 | 292
Marfan Syndrome 3 | 15
Mitral Valve Prolapse Syndrome 3 | 39
Mitral regurgitation, mild 3 | 32
Mitral valve insufficiency 3 | 49
Mitral valve prolapse 3 | 14
Myopia 3 | 176
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
tuberculosis 3 | 2,010
Acquired metabolic disease 2 | 336
Adducted thumb 2 | 22
Arachnodactyly 2 | 49
Brachycephaly 2 | 88
Brachydactyly 2 | 156
Broad cranium shape 2 | 88
Broad flat nasal bridge 2 | 236
Cardiomegaly 2 | 116
Chest Pain 2 | 38
Class III malocclusion 2 | 78
Concave bridge of nose 2 | 195
Congestive heart failure 2 | 113
Contracture 2 | 96
Contracture of joint 2 | 93
Coronary artery disease 2 | 268
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Generalized elastolysis 2 | 24
Generalized osteopenia 2 | 99
Hanging skin 2 | 24
Homocystinuria 2 | 21
Hypertrophy of lower jaw 2 | 78
Hypotrophic malar bone 2 | 129
Impaired cognition 2 | 96
Increased size of mandible 2 | 78
Kyphoscoliosis deformity of spine 2 | 60
Large intestine cancer 2 | 126
Liver Cirrhosis, Experimental 2 | 769
Long narrow head 2 | 75
Long philtrum 2 | 137
Low Vision 2 | 174
Malar flattening 2 | 129
Mandibular hyperplasia 2 | 78
Melanoma 2 | 711
Mental impairment 2 | 95
Motor delay 2 | 147
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Nasal bridge wide 2 | 236
No development of motor milestones 2 | 147
Osteopenia 2 | 99
Pectus excavatum 2 | 100
Pseudoxanthoma elasticum 2 | 18
Pulmonary Stenosis 2 | 45
Short nose 2 | 132
Skin cancer 2 | 469
Turridolichocephaly 2 | 75
Visual Impairment 2 | 174
Wide skull shape 2 | 88
fascioscapulohumeral muscular dystrophy 2 | 100
interstitial lung disease 2 | 298
mandibular excess (physical finding) 2 | 78
medulloblastoma 2 | 720

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145

Jensen-TM Tissue

Nuchal ligament 10 | 10
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Transmembrane and TPR repeat-containing protein 1 TMTC1 Tbio Non-IDG -2.44319 270.8 57
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Fibrillin-2 FBN2 Tbio Non-IDG -2.46578 287.6 123
A disintegrin and metalloproteinase with thrombospondin motifs 10 ADAMTS10 Tbio Enzyme -1.35665 21.7 120
Importin-5 IPO5 Tbio Non-IDG -2.18052 149.5 122
Microfibrillar-associated protein 2 MFAP2 Tbio Non-IDG -1.84472 72.8 129
ADAMTS-like protein 4 ADAMTSL4 Tbio Non-IDG -1.31166 21.8 64
Microfibrillar-associated protein 5 MFAP5 Tbio Non-IDG -1.48577 34.1 149