Development Level

Tbio 23 | 11,445
Tchem 9 | 1,598
Tdark 6 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal limb morphology 2 | 13
abnormal tail morphology 2 | 25
decreased basophil cell number 2 | 16
decreased circulating insulin ... 2 | 76
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb bud morphology 1 | 17
abnormal neural tube closure 1 | 46
absent startle reflex 1 | 24
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
spina bifida 1 | 2
syndactyly 1 | 23

Disease

Carcinoma 27 | 11,493
ovarian cancer 17 | 8,520
glioblastoma 15 | 5,792
osteosarcoma 15 | 7,950
Alzheimer's disease 13 | 658
Toxic encephalopathy 12 | 141
ependymoma 12 | 4,679
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
psoriasis 11 | 6,694
Breast cancer 9 | 3,578
Dementia 9 | 175
adult high grade glioma 9 | 3,801
diabetes mellitus 9 | 1,728
Cancer 8 | 2,499
lung carcinoma 8 | 2,843
Amyotrophic lateral sclerosis 7 | 451
Depressive disorder 7 | 409
Parkinson's disease 7 | 392
astrocytic glioma 7 | 2,597
lung adenocarcinoma 7 | 2,716
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Brain disease 6 | 96
Huntington's disease 6 | 76
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
Schizophrenia 6 | 1,160
group 3 medulloblastoma 6 | 4,104
invasive ductal carcinoma 6 | 2,951
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Alzheimer Disease 5 | 83
Amyloidosis 5 | 67
Cerebrovascular disease 5 | 238
Down syndrome 5 | 499
Intellectual disability 5 | 1,016
Mental Depression 5 | 333
Nerve Degeneration 5 | 121
Seizures 5 | 596
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
non-small cell lung cancer 5 | 2,890
Bipolar Disorder 4 | 666
Deglutition Disorders 4 | 132
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Neurodegenerative Disorders 4 | 79
Parkinsonian Disorders 4 | 56
Pick disease 4 | 1,894
active Crohn's disease 4 | 922
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Adult onset 3 | 82
Anxiety 3 | 136
Anxiety disease 3 | 113
Apathy 3 | 16
Aphasia 3 | 26
Disease Models, Animal 3 | 155
Dysarthria 3 | 192
Eye disease 3 | 62
Forgetful 3 | 40
Gliosis 3 | 56
Heart disease 3 | 306
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Liver disease 3 | 237
Memory Loss 3 | 40
Memory impairment 3 | 40
Mood Disorders 3 | 184
Muscle Spasticity 3 | 195
Myoclonus 3 | 74
Myopathy 3 | 185
Neuroblastoma 3 | 80
Neurofibrillary degeneration (morphologic abnormality) 3 | 9
Neuronal loss 3 | 25
Obesity 3 | 678
Osteoporosis 3 | 363
Personality change 3 | 23
Rapidly progressive 3 | 27
Rapidly progressive disorder 3 | 27
Rheumatoid arthritis 3 | 1,191
Splenomegaly 3 | 190
Vascular disease 3 | 319
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010

Tissue

Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Skin and soft tissues 36 | 17,230
Digestive Tract 35 | 17,369
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Urinary Tract 35 | 16,678
Blood and immune system 34 | 16,909
Respiratory system 34 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 10 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

Jensen-TM Tissue

Neuro-2a cell 38 | 38
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caskin-2 CASKIN2 Tdark Non-IDG -0.21450 1.97 118
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Huntingtin-interacting protein K HYPK Tbio Non-IDG -0.84672 8.89 4
Docking protein 6 DOK6 Tbio Non-IDG -0.45629 3.37 117
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Alternative prion protein PRNP Tbio Non-IDG -3.45326 5611.1 0
Seizure protein 6 homolog SEZ6 Tdark Non-IDG -0.88797 8.64 36
Transmembrane protein 132A TMEM132A Tdark Non-IDG -0.23045 2.47 54