Development Level

Tbio 104 | 11,178
Tchem 12 | 1,885
Tdark 4 | 6,569
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
abnormal neural tube closure 5 | 46
preweaning lethality, incomple... 5 | 499
abnormal placenta size 4 | 20
impaired glucose tolerance 4 | 75
increased total body fat amoun... 4 | 134
mammalian phenotype 4 | 17
prenatal lethality prior to he... 4 | 87
abnormal craniofacial morpholo... 3 | 33
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
embryonic growth retardation 3 | 106
enlarged lymph nodes 3 | 37
pale yolk sac 3 | 25
pallor 3 | 34
prenatal lethality 3 | 28
abnormal QT variability 2 | 10
abnormal allantois morphology 2 | 8
abnormal eye morphology 2 | 68
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal heart morphology 2 | 162
abnormal hindbrain development 2 | 16
abnormal hindbrain morphology 2 | 10
abnormal limb bud morphology 2 | 17
abnormal midbrain development 2 | 20
abnormal midbrain morphology 2 | 10
abnormal neural tube morpholog... 2 | 12
abnormal pericardium morpholog... 2 | 26
abnormal snout morphology 2 | 23
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased fasted circulating g... 2 | 65
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased startle reflex 2 | 112
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal left-right axis patte... 1 | 2
abnormal liver size 1 | 5
abnormal locomotor activation 1 | 16
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal ovary morphology 1 | 7
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cleft palate 1 | 8
cyanosis 1 | 7
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased cardiac stroke volum... 1 | 6
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased startle reflex 1 | 75
edema 1 | 59
enlarged heart atrium 1 | 4
enlarged ovary 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
long tibia 1 | 25
pale liver 1 | 6
prolonged PR interval 1 | 15
shortened QT interval 1 | 4
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 79 | 11,192
ovarian cancer 49 | 8,297
psoriasis 49 | 6,514
Cancer 45 | 2,388
osteosarcoma 44 | 7,766
ependymoma 39 | 4,559
atypical teratoid / rhabdoid tumor 37 | 4,971
glioblastoma 37 | 5,635
medulloblastoma, large-cell 36 | 6,086
malignant mesothelioma 34 | 3,135
lung cancer 32 | 4,607
Breast cancer 30 | 3,469
spina bifida 30 | 1,053
Astrocytoma, Pilocytic 29 | 3,006
group 3 medulloblastoma 27 | 4,002
Kidney cancer 26 | 2,548
Cleft Palate 22 | 265
Schizophrenia 22 | 1,136
pituitary cancer 22 | 1,915
Autosomal recessive predisposition 21 | 1,407
Cleft Lip 21 | 141
adult high grade glioma 21 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,872
oligodendroglioma 20 | 2,768
Epilepsy 19 | 775
Intellectual disability 19 | 998
Seizures 19 | 584
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,204
Dull intelligence 18 | 634
Low intelligence 18 | 634
Mental Retardation 18 | 634
Mental deficiency 18 | 634
Poor school performance 18 | 634
breast carcinoma 18 | 1,589
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,902
lung carcinoma 18 | 2,755
non-small cell lung cancer 18 | 2,799
subependymal giant cell astrocytoma 18 | 2,230
Muscle hypotonia 17 | 562
colon cancer 17 | 1,428
invasive ductal carcinoma 17 | 2,867
primitive neuroectodermal tumor 17 | 2,957
interstitial cystitis 16 | 2,237
pancreatic cancer 16 | 2,322
Cognitive delay 15 | 596
Global developmental delay 15 | 596
Mental and motor retardation 15 | 596
ductal carcinoma in situ 15 | 1,686
group 4 medulloblastoma 15 | 1,806
Holoprosencephaly 14 | 52
Short stature 14 | 514
Craniofacial Abnormalities 13 | 141
astrocytic glioma 13 | 2,530
Breast Neoplasms 12 | 423
Polydactyly 12 | 106
cystic fibrosis 12 | 1,629
diabetes mellitus 12 | 1,683
medulloblastoma 12 | 702
Neural Tube Defects 11 | 29
Small head 11 | 366
Strabismus 11 | 265
Bipolar Disorder 10 | 646
Congenital heart disease 10 | 91
Cryptorchidism 10 | 287
Down syndrome 10 | 480
Hydrocephalus 10 | 148
Mammary Neoplasms 10 | 403
Parkinson's disease 10 | 378
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,911
pediatric high grade glioma 10 | 1,035
Acquired scoliosis 9 | 274
Anencephaly 9 | 26
Autistic Disorder 9 | 358
Curvature of spine 9 | 275
Microphthalmia 9 | 72
Nervous System Diseases 9 | 50
Orbital separation excessive 9 | 240
Osteoporosis 9 | 348
Stomach Neoplasms 9 | 287
Uranostaphyloschisis 9 | 162
fibroadenoma 9 | 538
lung adenocarcinoma 9 | 2,627
nervous system disorder 9 | 50
Abnormally small eyeball 8 | 94
Alzheimer's disease 8 | 640
Brachydactyly 8 | 154
Decreased size of eyeball 8 | 94
Gastrointestinal Stromal Tumors 8 | 46
Highly variable severity 8 | 149
Hirschsprung's disease 8 | 44
Liver cancer 8 | 589
Low set ears 8 | 178
Microphthalmos 8 | 95
Obesity 8 | 655
Sensorineural Hearing Loss (disorder) 8 | 281
Synostosis 8 | 15
Variable expressivity 8 | 149
atypical teratoid/rhabdoid tumor 8 | 349
gastric carcinoma 8 | 781
Micrognathism 7 | 273

Tissue

Endocrine System 116 | 18,159
Skin and soft tissues 105 | 17,230
Digestive Tract 103 | 17,369
Female tissues 103 | 17,400
Nervous System 103 | 16,725
Male tissues 100 | 17,142
Liver and Pancreas 92 | 16,750
Urinary Tract 92 | 16,678
Blood and immune system 91 | 16,909
Respiratory system 87 | 16,393
Cardiovascular System 77 | 15,192

Target Family

Transcription Factor 58 | 1,400
Non-IDG 44 | 12,091
Enzyme 11 | 4,145
GPCR 4 | 408
Kinase 2 | 634
Epigenetic 1 | 242
TF/Epigenetic 1 | 38
Transporter 1 | 473

Jensen-TM Tissue

Neural tube 122 | 122
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Homeobox protein Nkx-2.2 NKX2-2 Tbio Transcription Factor -2.06202 108.0 379
Homeobox protein DBX1 DBX1 Tbio Transcription Factor -1.28715 33.6 84
Transcription factor SOX-1 SOX1 Tbio Transcription Factor -2.05328 109.0 220
Homeobox protein engrailed-1 EN1 Tbio Transcription Factor -2.44551 264.6 188
Protein Shroom3 SHROOM3 Tbio Non-IDG -1.57599 36.8 31
LIM/homeobox protein Lhx3 LHX3 Tbio Transcription Factor -1.99937 96.2 108
Forkhead box protein G1 FOXG1 Tbio Transcription Factor -2.63715 438.9 214
Methionine synthase reductase MTRR Tbio Enzyme -2.46986 307.5 53
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389