Development Level

Tbio 698 | 11,445
Tchem 299 | 1,598
Tclin 160 | 613
Tdark 13 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 95 | 979
preweaning lethality, incomple... 40 | 499
embryonic lethality prior to t... 38 | 278
abnormal embryo size 25 | 220
enlarged heart 23 | 210
embryonic lethality prior to o... 21 | 239
abnormal behavior 20 | 298
decreased vertical activity 20 | 208
decreased total body fat amoun... 19 | 207
increased lean body mass 18 | 172
increased total body fat amoun... 17 | 134
abnormal heart morphology 15 | 162
increased circulating alkaline... 15 | 122
decreased body weight 13 | 161
decreased lean body mass 13 | 135
increased startle reflex 13 | 112
embryonic growth retardation 12 | 106
abnormal gait 11 | 69
increased circulating choleste... 11 | 66
abnormal retina morphology 10 | 71
hyperactivity 10 | 148
prolonged ST segment 10 | 36
short tibia 10 | 97
abnormal bone structure 9 | 187
abnormal lens morphology 9 | 81
abnormal seminal vesicle morph... 9 | 114
cataract 9 | 92
decreased bone mineral density 9 | 126
decreased lymphocyte cell numb... 9 | 83
decreased mean corpuscular vol... 9 | 79
edema 9 | 59
hypoactivity 9 | 132
improved glucose tolerance 9 | 79
increased bone mineral content 9 | 108
increased heart weight 9 | 62
increased mean corpuscular vol... 9 | 92
prolonged QT interval 9 | 38
decreased bone mineral content 8 | 151
decreased circulating triglyce... 8 | 79
decreased prepulse inhibition 8 | 82
increased circulating HDL chol... 8 | 80
increased hemoglobin content 8 | 45
increased monocyte cell number 8 | 63
increased neutrophil cell numb... 8 | 46
limb grasping 8 | 41
decreased blood urea nitrogen ... 7 | 51
decreased body length 7 | 101
decreased circulating amylase ... 7 | 28
decreased circulating calcium ... 7 | 36
decreased circulating creatini... 7 | 39
decreased grip strength 7 | 116
decreased startle reflex 7 | 75
impaired righting response 7 | 26
male infertility 7 | 123
small superior vagus ganglion 7 | 74
abnormal kidney morphology 6 | 65
decreased circulating HDL chol... 6 | 68
decreased circulating alkaline... 6 | 46
decreased circulating glucose ... 6 | 126
decreased circulating insulin ... 6 | 76
decreased erythrocyte cell num... 6 | 62
decreased neutrophil cell numb... 6 | 42
impaired glucose tolerance 6 | 75
increased body length 6 | 32
increased bone mineral density 6 | 72
increased circulating total pr... 6 | 28
increased hematocrit 6 | 46
increased leukocyte cell numbe... 6 | 47
increased or absent threshold ... 6 | 101
abnormal behavioral response t... 5 | 66
abnormal bone mineralization 5 | 38
abnormal femur morphology 5 | 14
abnormal lung morphology 5 | 26
abnormal sleep behavior 5 | 70
abnormal testis morphology 5 | 43
decreased circulating LDL chol... 5 | 38
decreased circulating alanine ... 5 | 47
decreased circulating bilirubi... 5 | 19
decreased circulating choleste... 5 | 93
decreased leukocyte cell numbe... 5 | 73
decreased red blood cell distr... 5 | 41
decreased spleen weight 5 | 10
increased circulating calcium ... 5 | 34
increased circulating iron lev... 5 | 30
increased circulating phosphat... 5 | 26
increased lymphocyte cell numb... 5 | 32
increased mean corpuscular hem... 5 | 96
prenatal lethality prior to he... 5 | 87
small testis 5 | 58
abnormal epididymis morphology 4 | 42
abnormal skin morphology 4 | 50
absent startle reflex 4 | 24
cardiovascular system phenotyp... 4 | 36
decreased circulating aspartat... 4 | 34
decreased circulating free fat... 4 | 31
decreased circulating serum al... 4 | 82
decreased fasted circulating g... 4 | 65
increased circulating serum al... 4 | 22
increased fasted circulating g... 4 | 76
pallor 4 | 34

Disease

Carcinoma 792 | 11,493
Cancer 621 | 2,499
ovarian cancer 617 | 8,520
psoriasis 587 | 6,694
osteosarcoma 530 | 7,950
glioblastoma 499 | 5,792
lung cancer 481 | 4,740
medulloblastoma, large-cell 443 | 6,241
atypical teratoid / rhabdoid tumor 391 | 5,112
diabetes mellitus 375 | 1,728
ependymoma 374 | 4,679
Breast cancer 364 | 3,578
malignant mesothelioma 345 | 3,232
invasive ductal carcinoma 326 | 2,951
lung adenocarcinoma 308 | 2,716
adult high grade glioma 307 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 304 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 302 | 3,291
non-small cell lung cancer 299 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 292 | 2,989
pancreatic cancer 292 | 2,398
lung carcinoma 286 | 2,843
Astrocytoma, Pilocytic 280 | 3,081
group 3 medulloblastoma 274 | 4,104
Hypertension 239 | 396
primitive neuroectodermal tumor 238 | 3,035
Autosomal recessive predisposition 236 | 1,442
Obesity 234 | 678
interstitial cystitis 234 | 2,312
cystic fibrosis 229 | 1,696
Kidney cancer 227 | 2,613
oligodendroglioma 220 | 2,850
breast carcinoma 216 | 1,638
Schizophrenia 214 | 1,160
ulcerative colitis 214 | 1,819
ductal carcinoma in situ 212 | 1,745
colon cancer 211 | 1,478
pituitary cancer 207 | 1,972
tuberculosis 203 | 2,010
subependymal giant cell astrocytoma 201 | 2,287
Heart disease 200 | 306
Kidney disease 190 | 430
astrocytic glioma 182 | 2,597
Vascular disease 178 | 319
pancreatic ductal adenocarcinoma liver metastasis 170 | 1,962
adrenocortical carcinoma 167 | 1,428
acute quadriplegic myopathy 165 | 1,158
group 4 medulloblastoma 163 | 1,855
Liver Cirrhosis, Experimental 161 | 769
Atherosclerosis 152 | 291
Hypertensive disease 150 | 292
Coronary artery disease 147 | 268
Rheumatoid arthritis 145 | 1,191
astrocytoma 142 | 1,146
Alzheimer's disease 141 | 658
Cerebrovascular disease 140 | 238
juvenile dermatomyositis 136 | 1,187
Bipolar Disorder 132 | 666
Myopathy 132 | 185
Depressive disorder 131 | 409
Epilepsy 131 | 792
primary pancreatic ductal adenocarcinoma 131 | 1,109
Arthritis 125 | 290
Pick disease 124 | 1,894
Asthma 123 | 385
Breast Neoplasms 123 | 445
Mammary Neoplasms 121 | 425
gastric carcinoma 117 | 807
Atopic dermatitis 113 | 952
dermatomyositis 113 | 966
Multiple myeloma 112 | 1,332
cutaneous lupus erythematosus 112 | 1,057
Prostatic Neoplasms 109 | 495
Duchenne muscular dystrophy 108 | 601
Seizures 108 | 596
Neuropathy 107 | 261
Intellectual disability 104 | 1,016
Liver disease 104 | 237
Hyperglycemia 103 | 137
Neurodegenerative disease 103 | 414
Heart failure 102 | 162
Melanoma 101 | 711
Mental Depression 101 | 333
Multiple Sclerosis 101 | 540
Osteoporosis 100 | 363
autosomal dominant Emery-Dreifuss muscular dystrophy 100 | 510
Short stature 99 | 531
Lung disease 94 | 142
Down syndrome 93 | 499
nasopharyngeal carcinoma 93 | 1,058
Muscle hypotonia 92 | 571
fibroadenoma 92 | 559
Endometriosis 91 | 540
Myocardial Infarction 90 | 151
Stomach Neoplasms 90 | 300
esophageal adenocarcinoma 90 | 737
pediatric high grade glioma 90 | 1,064
Anemia 88 | 365
active ulcerative colitis 88 | 764
Parkinson's disease 84 | 392

Tissue

Endocrine System 1,142 | 18,159
Digestive Tract 1,140 | 17,369
Skin and soft tissues 1,128 | 17,230
Female tissues 1,123 | 17,400
Male tissues 1,118 | 17,142
Urinary Tract 1,110 | 16,678
Blood and immune system 1,105 | 16,909
Liver and Pancreas 1,105 | 16,750
Nervous System 1,086 | 16,725
Respiratory system 1,084 | 16,393
Cardiovascular System 1,045 | 15,192

Target Family

Non-IDG 563 | 12,091
Enzyme 240 | 4,145
Transcription Factor 104 | 1,400
Kinase 94 | 634
Ion Channel 67 | 344
GPCR 42 | 408
Transporter 24 | 473
Epigenetic 22 | 242
Nuclear Receptor 13 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Muscle 1,170 | 1,170
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Caveolae-associated protein 4 CAVIN4 Tbio Non-IDG -1.43474 31.1 70
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431