Development Level

Tbio 601 | 10,625
Tchem 339 | 1,890
Tclin 153 | 602
Tdark 17 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

preweaning lethality, complete... 62 | 633
embryonic lethality prior to t... 25 | 187
preweaning lethality, incomple... 25 | 260
abnormal behavior 20 | 226
abnormal embryo size 16 | 112
decreased body weight 16 | 174
decreased lean body mass 16 | 195
decreased bone mineral density 15 | 126
decreased total body fat amoun... 15 | 186
increased circulating alkaline... 15 | 119
decreased bone mineral content 14 | 157
embryonic lethality prior to o... 13 | 148
enlarged heart 13 | 111
abnormal retina morphology 11 | 100
decreased body length 11 | 108
decreased grip strength 10 | 123
increased or absent threshold ... 10 | 128
abnormal gait 9 | 51
increased mean corpuscular vol... 9 | 91
abnormal lens morphology 8 | 73
abnormal neural tube closure 8 | 37
decreased circulating insulin ... 8 | 75
decreased startle reflex 8 | 48
hypoactivity 8 | 89
increased circulating choleste... 8 | 53
increased lean body mass 8 | 107
abnormal bone structure 7 | 131
abnormal hindbrain development 7 | 24
decreased circulating HDL chol... 7 | 77
decreased circulating alanine ... 7 | 53
decreased circulating triglyce... 7 | 83
hyperactivity 7 | 108
increased hemoglobin content 7 | 45
increased mean corpuscular hem... 7 | 93
limb grasping 7 | 35
abnormal forebrain development 6 | 18
abnormal heart morphology 6 | 51
abnormal midbrain development 6 | 22
cataract 6 | 26
decreased blood urea nitrogen ... 6 | 31
decreased circulating calcium ... 6 | 33
decreased circulating choleste... 6 | 85
decreased circulating glucose ... 6 | 121
decreased prepulse inhibition 6 | 52
improved glucose tolerance 6 | 56
increased bone mineral content 6 | 92
increased circulating HDL chol... 6 | 63
increased hematocrit 6 | 36
increased total body fat amoun... 6 | 57
short tibia 6 | 82
abnormal behavioral response t... 5 | 52
abnormal bone mineralization 5 | 55
abnormal epididymis morphology 5 | 31
abnormal sleep behavior 5 | 63
abnormal tooth morphology 5 | 24
decreased circulating LDL chol... 5 | 37
decreased circulating alkaline... 5 | 41
decreased circulating amylase ... 5 | 24
decreased circulating creatini... 5 | 31
decreased fasted circulating g... 5 | 49
decreased heart weight 5 | 44
decreased mean corpuscular vol... 5 | 50
enlarged epididymis 5 | 27
impaired righting response 5 | 19
increased blood urea nitrogen ... 5 | 44
increased body weight 5 | 42
increased bone mineral density 5 | 52
increased circulating phosphat... 5 | 24
increased circulating triglyce... 5 | 24
increased fasted circulating g... 5 | 68
increased grip strength 5 | 83
increased heart weight 5 | 37
tremors 5 | 34
abnormal femur morphology 4 | 14
absent startle reflex 4 | 15
cardiovascular system phenotyp... 4 | 35
decreased circulating chloride... 4 | 32
decreased circulating free fat... 4 | 39
decreased eosinophil cell numb... 4 | 41
decreased erythrocyte cell num... 4 | 43
decreased leukocyte cell numbe... 4 | 54
decreased threshold for audito... 4 | 32
hydrops fetalis 4 | 22
increased circulating potassiu... 4 | 31
increased startle reflex 4 | 38
small testis 4 | 37
abnormal coat/hair pigmentatio... 3 | 54
abnormal lung morphology 3 | 15
abnormal vocalization 3 | 21
decreased T cell number 3 | 31
decreased circulating iron lev... 3 | 25
decreased rib number 3 | 59
decreased total retina thickne... 3 | 20
enlarged spleen 3 | 26
impaired glucose tolerance 3 | 52
increased circulating calcium ... 3 | 32
increased circulating total pr... 3 | 20
increased erythrocyte cell num... 3 | 26
increased exploration in new e... 3 | 56
increased respiratory quotient 3 | 12

Disease

ovarian cancer 588 | 8,484
Cancer 575 | 2,346
psoriasis 564 | 6,685
osteosarcoma 504 | 7,933
glioblastoma 446 | 5,572
lung cancer 445 | 4,466
medulloblastoma, large-cell 419 | 6,234
diabetes mellitus 338 | 1,663
invasive ductal carcinoma 318 | 2,950
malignant mesothelioma 314 | 3,162
atypical teratoid / rhabdoid tumor 313 | 4,369
lung adenocarcinoma 299 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 297 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 293 | 2,956
Breast cancer 285 | 3,094
non-small cell lung cancer 284 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 283 | 2,988
lung carcinoma 278 | 2,844
pancreatic cancer 273 | 2,300
pilocytic astrocytoma 267 | 3,086
ulcerative colitis 248 | 2,087
primitive neuroectodermal tumor 229 | 3,031
cystic fibrosis 224 | 1,665
interstitial cystitis 224 | 2,299
pediatric high grade glioma 224 | 2,712
oligodendroglioma 212 | 2,849
Carcinoma 210 | 2,147
Obesity 210 | 616
ductal carcinoma in situ 209 | 1,745
colon cancer 204 | 1,475
breast carcinoma 202 | 1,614
pituitary cancer 198 | 1,972
Hypertension 192 | 287
Heart disease 191 | 279
ependymoma 191 | 2,514
subependymal giant cell astrocytoma 191 | 2,287
Kidney disease 182 | 396
astrocytoma 171 | 1,493
tuberculosis 169 | 1,557
Vascular disease 167 | 281
group 4 medulloblastoma 167 | 1,875
acute quadriplegic myopathy 165 | 1,157
adrenocortical carcinoma 163 | 1,427
primary pancreatic ductal adenocarcinoma 156 | 1,271
adult high grade glioma 154 | 2,148
posterior fossa group A ependymoma 151 | 1,511
Atherosclerosis 144 | 275
Rheumatoid Arthritis 141 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 136 | 1,795
astrocytic glioma 135 | 2,241
Cerebrovascular disease 134 | 231
Alzheimer's disease 132 | 644
juvenile dermatomyositis 131 | 1,189
Coronary artery disease 127 | 240
gastric carcinoma 121 | 832
Pick disease 120 | 1,893
sonic hedgehog group medulloblastoma 119 | 1,482
Mammary Neoplasms 116 | 410
Arthritis 115 | 248
Asthma 115 | 349
group 3 medulloblastoma 113 | 2,254
medulloblastoma 111 | 1,524
cutaneous lupus erythematosus 109 | 1,056
Myopathy 107 | 128
dermatomyositis 107 | 933
Atopic dermatitis 106 | 944
Duchenne muscular dystrophy 106 | 602
Prostatic Neoplasms 105 | 471
Multiple myeloma 104 | 1,327
Hypertensive disease 101 | 193
autosomal dominant Emery-Dreifuss muscular dystrophy 94 | 499
Liver disease 93 | 219
Lung disease 91 | 132
Multiple Sclerosis 90 | 498
posterior fossa group B ependymoma 90 | 1,530
Endometriosis 89 | 535
Hyperglycemia 89 | 120
Metabolic syndrome X 89 | 155
Down syndrome 88 | 548
esophageal adenocarcinoma 88 | 737
fibroadenoma 88 | 557
nasopharyngeal carcinoma 87 | 1,056
Neurodegenerative disease 86 | 383
atypical teratoid/rhabdoid tumor 86 | 1,095
Schizophrenia 83 | 501
Stomach Neoplasms 83 | 282
Neuropathy 81 | 210
Parkinson's disease 77 | 364
Myocardial Infarction 76 | 126
Osteoporosis 76 | 257
Amyotrophic Lateral Sclerosis 73 | 431
aldosterone-producing adenoma 72 | 664
Inflammatory bowel disease 71 | 142
Liver carcinoma 71 | 217
Neoplasm Metastasis 71 | 138
active Crohn's disease 71 | 918
Diabetes Mellitus, Experimental 70 | 106
Hypersensitivity reaction type II disease 70 | 235
Myocardial Ischemia 70 | 169
non-small cell lung carcinoma 69 | 413

Tissue

Female tissues 1,098 | 18,647
Digestive Tract 1,096 | 18,473
Nervous System 1,092 | 18,561
Liver and Pancreas 1,091 | 18,136
Endocrine System 1,090 | 18,512
Skin and soft tissues 1,087 | 18,115
Blood and immune system 1,085 | 17,995
Urinary Tract 1,085 | 18,444
Male tissues 1,080 | 17,969
Cardiovascular System 1,079 | 17,958
Respiratory system 1,071 | 17,484

Target Family

Non-IDG 528 | 11,971
Enzyme 232 | 4,146
Transcription Factor 98 | 1,400
Kinase 89 | 634
Ion Channel 66 | 341
GPCR 42 | 406
Transporter 23 | 473
Epigenetic 18 | 242
Nuclear Receptor 13 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Muscle 1,110 | 1,110
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788