Development Level

Tbio 68 | 11,178
Tchem 11 | 1,885
Tclin 2 | 612
Tdark 2 | 6,569

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 5 | 278
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
abnormal kidney morphology 2 | 65
decreased bone mineral content 2 | 151
embryonic lethality prior to o... 2 | 239
prenatal lethality 2 | 28
small testis 2 | 58
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
absent epididymis 1 | 3
corneal opacity 1 | 32
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating aspartat... 1 | 15
increased circulating potassiu... 1 | 29
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
irregularly shaped pupil 1 | 7
no spontaneous movement 1 | 1
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
small heart 1 | 10
small superior vagus ganglion 1 | 74

Disease

Cancer 42 | 2,388
Carcinoma 41 | 11,192
psoriasis 33 | 6,514
ovarian cancer 26 | 8,297
medulloblastoma, large-cell 25 | 6,086
Breast cancer 23 | 3,469
osteosarcoma 23 | 7,766
lung cancer 22 | 4,607
glioblastoma 21 | 5,635
interstitial cystitis 18 | 2,237
malignant mesothelioma 18 | 3,135
non-small cell lung cancer 18 | 2,799
group 3 medulloblastoma 17 | 4,002
Congenital heart disease 16 | 91
atypical teratoid / rhabdoid tumor 16 | 4,971
lung adenocarcinoma 16 | 2,627
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,872
lung carcinoma 14 | 2,755
adult high grade glioma 13 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,204
Astrocytoma, Pilocytic 12 | 3,006
cystic fibrosis 12 | 1,629
invasive ductal carcinoma 12 | 2,867
Autosomal recessive predisposition 11 | 1,407
ependymoma 11 | 4,559
Cleft Palate 10 | 265
Short stature 10 | 514
Tetralogy of Fallot 10 | 66
breast carcinoma 10 | 1,589
diabetes mellitus 10 | 1,683
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,902
pancreatic cancer 10 | 2,322
Craniofacial Abnormalities 9 | 141
Kidney cancer 9 | 2,548
Schizophrenia 9 | 1,136
colon cancer 9 | 1,428
Cryptorchidism 8 | 287
ulcerative colitis 8 | 1,765
Brachydactyly 7 | 154
Cognitive delay 7 | 596
Global developmental delay 7 | 596
Mental and motor retardation 7 | 596
Osteoporosis 7 | 348
Parkinson's disease 7 | 378
Ventricular Septal Defects 7 | 113
astrocytic glioma 7 | 2,530
ductal carcinoma in situ 7 | 1,686
esophageal adenocarcinoma 7 | 696
group 4 medulloblastoma 7 | 1,806
pituitary cancer 7 | 1,915
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 6 | 21
Cleft Lip 6 | 141
DiGeorge syndrome 6 | 46
Dull intelligence 6 | 634
Holoprosencephaly 6 | 52
Intellectual disability 6 | 998
Low intelligence 6 | 634
Mental Retardation 6 | 634
Mental deficiency 6 | 634
Muscle hypotonia 6 | 562
Obesity 6 | 655
Poor school performance 6 | 634
oligodendroglioma 6 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
primitive neuroectodermal tumor 6 | 2,957
sonic hedgehog group medulloblastoma 6 | 459
Amyotrophic lateral sclerosis 5 | 437
Atrioventricular Septal Defect 5 | 22
Bilateral fifth finger clinodactyly 5 | 109
Breast Neoplasms 5 | 423
Broad flat nasal bridge 5 | 232
Broad hallux 5 | 29
Congenital diaphragmatic hernia 5 | 66
Curvature of little finger 5 | 109
Fatigue 5 | 176
Heart disease 5 | 288
Hypoplastic mandible condyle 5 | 273
Mammary Neoplasms 5 | 403
Mandibular hypoplasia 5 | 273
Micrognathism 5 | 273
Nasal bridge wide 5 | 232
Preauricular Fistulae, Congenital 5 | 27
Preauricular dimple 5 | 27
Preauricular sinus 5 | 27
Rheumatoid arthritis 5 | 1,156
Small head 5 | 366
Strabismus 5 | 265
Uranostaphyloschisis 5 | 162
active ulcerative colitis 5 | 736
fibroadenoma 5 | 538
gastric carcinoma 5 | 781
subependymal giant cell astrocytoma 5 | 2,230
tuberculosis 5 | 1,963
Atopic dermatitis 4 | 915
Bipolar Disorder 4 | 646
Immune system cancer 4 | 136
Umbilical hernia 4 | 88
acute quadriplegic myopathy 4 | 1,133
nasopharyngeal carcinoma 4 | 1,024
spina bifida 4 | 1,053

Tissue

Digestive Tract 75 | 17,369
Endocrine System 75 | 18,159
Female tissues 74 | 17,400
Male tissues 73 | 17,142
Skin and soft tissues 72 | 17,230
Liver and Pancreas 70 | 16,750
Urinary Tract 69 | 16,678
Respiratory system 66 | 16,393
Blood and immune system 65 | 16,909
Nervous System 61 | 16,725
Cardiovascular System 57 | 15,192

Target Family

Transcription Factor 49 | 1,400
Non-IDG 23 | 12,091
Kinase 5 | 634
Enzyme 3 | 4,145
GPCR 2 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Mesoderm 83 | 83
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Runt-related transcription factor 1 RUNX1 Tbio Transcription Factor -3.25790 1899.3 798
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266
E3 SUMO-protein ligase EGR2 EGR2 Tbio Transcription Factor -2.55244 341.9 344
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.19918 1373.3 664
Ephrin type-A receptor 4 EPHA4 Tchem Kinase -2.37243 255.5 495
Transcription factor GATA-4 GATA4 Tbio Transcription Factor -2.90202 763.9 496
Endothelial transcription factor GATA-2 GATA2 Tbio Transcription Factor -2.70355 475.5 354
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570