Development Level

Tbio 71 | 10,625
Tchem 11 | 1,890
Tclin 3 | 602
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, complete... 10 | 633
abnormal embryo size 3 | 112
embryonic lethality prior to t... 3 | 187
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
small testis 2 | 37
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat- hair morphology 1 | 18
abnormal coping response 1 | 12
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 3
abnormal seminal vesicle morph... 1 | 47
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
absent epididymis 1 | 2
corneal opacity 1 | 25
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased lumbar vertebrae num... 1 | 62
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased circulating phosphat... 1 | 24
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
kinked tail 1 | 3
no spontaneous movement 1 | 1
prenatal lethality 1 | 16
short tibia 1 | 82
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20

Disease

Cancer 47 | 2,346
psoriasis 39 | 6,685
ovarian cancer 33 | 8,491
medulloblastoma, large-cell 29 | 6,234
osteosarcoma 29 | 7,933
lung cancer 27 | 4,473
glioblastoma 25 | 5,572
Breast cancer 24 | 3,098
interstitial cystitis 23 | 2,299
non-small cell lung cancer 23 | 2,798
lung adenocarcinoma 22 | 2,714
malignant mesothelioma 22 | 3,163
atypical teratoid / rhabdoid tumor 19 | 4,369
lung carcinoma 18 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
invasive ductal carcinoma 17 | 2,950
Congenital heart disease 16 | 63
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
cystic fibrosis 15 | 1,670
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
pilocytic astrocytoma 14 | 3,086
breast carcinoma 13 | 1,614
colon cancer 13 | 1,475
group 3 medulloblastoma 13 | 2,254
adult high grade glioma 12 | 2,148
pancreatic cancer 11 | 2,300
sonic hedgehog group medulloblastoma 11 | 1,482
ductal carcinoma in situ 10 | 1,745
ependymoma 10 | 2,514
ulcerative colitis 10 | 2,087
Craniofacial Abnormalities 9 | 147
Tetralogy of Fallot 9 | 38
diabetes mellitus 9 | 1,663
oligodendroglioma 9 | 2,849
pediatric high grade glioma 9 | 2,712
posterior fossa group A ependymoma 9 | 1,511
Rheumatoid Arthritis 8 | 1,170
group 4 medulloblastoma 8 | 1,875
medulloblastoma 8 | 1,524
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,031
subependymal giant cell astrocytoma 8 | 2,287
Carcinoma 7 | 2,147
Colorectal Neoplasms 7 | 217
Heart disease 7 | 279
Mammary Neoplasms 7 | 410
Parkinson's disease 7 | 364
astrocytic glioma 7 | 2,241
esophageal adenocarcinoma 7 | 737
Atopic dermatitis 6 | 944
Cleft palate 6 | 125
DiGeorge syndrome 6 | 46
Holoprosencephaly 6 | 52
acute quadriplegic myopathy 6 | 1,157
fibroadenoma 6 | 557
gastric carcinoma 6 | 832
primary pancreatic ductal adenocarcinoma 6 | 1,271
Amyotrophic Lateral Sclerosis 5 | 432
Autistic Disorder 5 | 320
Congenital Heart Defects 5 | 37
Diaphragmatic Hernia 5 | 40
Obesity 5 | 616
Osteoporosis 5 | 259
active Crohn's disease 5 | 918
active ulcerative colitis 5 | 477
cutaneous lupus erythematosus 5 | 1,056
nasopharyngeal carcinoma 5 | 1,056
tuberculosis 5 | 1,563
Atrial heart septal defect 4 | 15
Barrett's esophagus 4 | 185
Cardiomyopathy 4 | 110
Cleft Lip 4 | 91
Congenital diaphragmatic hernia 4 | 44
Conotruncal heart malformations 4 | 10
Ebstein anomaly 4 | 13
Holt-Oram syndrome 4 | 14
Ostium secundum atrial septal defect 4 | 8
Pancreatic agenesis 4 | 14
Polydactyly 4 | 93
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4 | 18
Renal agenesis 4 | 25
Visceral heterotaxy 4 | 12
adrenocortical carcinoma 4 | 1,427
aldosterone-producing adenoma 4 | 664
atypical teratoid/rhabdoid tumor 4 | 1,095
facioscapulohumeral dystrophy 4 | 286
non primary Sjogren syndrome sicca 4 | 840
non-inflammatory breast cancer 4 | 208
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
primary Sjogren syndrome 4 | 788
spina bifida 4 | 1,064
urothelial carcinoma 4 | 318
ventricular septal defect 4 | 20
Down syndrome 3 | 548
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 334
Vascular disease 3 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
nephrosclerosis 3 | 329

Tissue

Endocrine System 85 | 18,511
Female tissues 85 | 18,646
Digestive Tract 84 | 18,472
Nervous System 84 | 18,560
Skin and soft tissues 84 | 18,114
Urinary Tract 83 | 18,443
Liver and Pancreas 82 | 18,135
Male tissues 82 | 17,968
Cardiovascular System 81 | 17,957
Blood and immune system 80 | 17,994
Respiratory system 78 | 17,483

Target Family

Transcription Factor 50 | 1,400
Non-IDG 26 | 11,969
Kinase 5 | 634
Enzyme 3 | 4,146
GPCR 2 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Mesoderm 87 | 87
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.04240 90.2 423
Frizzled-1 FZD1 Tbio GPCR -2.04125 74.3 233
Transcription factor 21 TCF21 Tbio Transcription Factor -1.77727 57.8 121
Transcription factor GATA-5 GATA5 Tbio Transcription Factor -1.94419 83.7 166
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.96037 90.3 180
T-box transcription factor TBX20 TBX20 Tbio Transcription Factor -1.73587 64.8 87
Runt-related transcription factor 1 RUNX1 Tbio Transcription Factor -3.23385 1789.0 751
Semaphorin-3A SEMA3A Tbio Non-IDG -2.66866 501.0 166
Follistatin FST Tbio Non-IDG -3.06086 1100.8 305