Development Level

Tbio 174 | 10,625
Tchem 59 | 1,890
Tclin 28 | 602

IMPC Term

preweaning lethality, complete... 16 | 633
decreased lean body mass 7 | 195
decreased bone mineral content 6 | 157
embryonic lethality prior to t... 6 | 187
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
abnormal bone structure 4 | 131
abnormal embryo size 4 | 112
cataract 4 | 26
abnormal lens morphology 3 | 73
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased heart weight 3 | 44
enlarged heart 3 | 111
hyperactivity 3 | 108
increased circulating alkaline... 3 | 119
increased vertical activity 3 | 18
limb grasping 3 | 35
abnormal behavioral response t... 2 | 52
abnormal coat/hair pigmentatio... 2 | 54
abnormal cornea morphology 2 | 24
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 18
abnormal gait 2 | 51
abnormal head morphology 2 | 10
abnormal hindbrain development 2 | 24
abnormal humerus morphology 2 | 11
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
cleft palate 2 | 6
decreased body weight 2 | 174
decreased grip strength 2 | 123
decreased kidney weight 2 | 7
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
hydrops fetalis 2 | 22
impaired pupillary reflex 2 | 14
impaired righting response 2 | 19
increased body weight 2 | 42
increased or absent threshold ... 2 | 128
increased respiratory quotient 2 | 12
short tibia 2 | 82
abnormal anxiety-related respo... 1 | 1
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal incisor color 1 | 2
abnormal kidney morphology 1 | 30
abnormal liver morphology 1 | 5
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
absent heartbeat 1 | 6
absent startle reflex 1 | 15
corneal opacity 1 | 25
cyanosis 1 | 6
decreased blood urea nitrogen ... 1 | 31
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased eosinophil cell numb... 1 | 41
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating chloride... 1 | 43
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
mydriasis 1 | 9
narrow eye opening 1 | 15
pale yolk sac 1 | 12
polycystic kidney 1 | 9
small testis 1 | 37
straub tail 1 | 26
tremors 1 | 34

Disease

Cancer 189 | 2,346
ovarian cancer 157 | 8,484
psoriasis 137 | 6,685
osteosarcoma 135 | 7,933
lung cancer 122 | 4,466
glioblastoma 118 | 5,572
Breast cancer 110 | 3,094
medulloblastoma, large-cell 99 | 6,234
invasive ductal carcinoma 98 | 2,950
pilocytic astrocytoma 98 | 3,086
malignant mesothelioma 93 | 3,162
pancreatic cancer 88 | 2,300
atypical teratoid / rhabdoid tumor 87 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 82 | 2,956
interstitial cystitis 81 | 2,299
lung adenocarcinoma 81 | 2,713
non-small cell lung cancer 81 | 2,798
cystic fibrosis 80 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 80 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 79 | 2,988
lung carcinoma 77 | 2,844
ulcerative colitis 77 | 2,087
pediatric high grade glioma 72 | 2,712
Carcinoma 71 | 2,147
ductal carcinoma in situ 71 | 1,745
oligodendroglioma 71 | 2,849
breast carcinoma 67 | 1,614
Mammary Neoplasms 59 | 410
pituitary cancer 58 | 1,972
diabetes mellitus 57 | 1,663
primary pancreatic ductal adenocarcinoma 57 | 1,271
Kidney disease 56 | 396
primitive neuroectodermal tumor 53 | 3,031
ependymoma 52 | 2,514
subependymal giant cell astrocytoma 50 | 2,287
colon cancer 48 | 1,475
posterior fossa group A ependymoma 48 | 1,511
adrenocortical carcinoma 47 | 1,427
tuberculosis 47 | 1,557
sonic hedgehog group medulloblastoma 44 | 1,482
group 4 medulloblastoma 43 | 1,875
astrocytoma 42 | 1,493
Prostatic Neoplasms 41 | 471
astrocytic glioma 41 | 2,241
Duchenne muscular dystrophy 40 | 602
Endometriosis 40 | 535
Heart disease 40 | 279
Rheumatoid Arthritis 40 | 1,160
nasopharyngeal carcinoma 40 | 1,056
gastric carcinoma 39 | 832
juvenile dermatomyositis 38 | 1,189
Adenoma 37 | 165
Neoplasm Metastasis 37 | 138
acute quadriplegic myopathy 37 | 1,157
Liver disease 36 | 219
Stomach Neoplasms 36 | 282
cutaneous lupus erythematosus 36 | 1,056
Vascular disease 35 | 281
Alzheimer's disease 34 | 644
Cleft palate 34 | 125
Neoplasm Invasiveness 34 | 127
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 499
esophageal adenocarcinoma 34 | 737
Lung Neoplasms 33 | 171
Osteoporosis 33 | 257
group 3 medulloblastoma 33 | 2,254
Arthritis 32 | 248
adult high grade glioma 32 | 2,148
Atherosclerosis 31 | 275
Atopic dermatitis 31 | 944
posterior fossa group B ependymoma 31 | 1,530
Craniofacial Abnormalities 30 | 147
non-small cell lung carcinoma 30 | 413
Pick disease 28 | 1,893
Liver carcinoma 27 | 217
Lung disease 27 | 132
Down syndrome 26 | 548
Neoplastic Cell Transformation 26 | 81
Pulmonary Fibrosis 26 | 66
Cerebrovascular disease 25 | 231
Hypertension 25 | 287
Liver Cirrhosis, Experimental 25 | 108
Obesity 25 | 616
Osteoarthritis 25 | 96
atypical teratoid/rhabdoid tumor 25 | 1,095
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
Colorectal Neoplasms 24 | 217
Asthma 23 | 349
Colonic Neoplasms 23 | 126
Adenocarcinoma 22 | 115
Cleft Lip 22 | 91
Liver Cirrhosis 22 | 101
Mammary Neoplasms, Experimental 22 | 150
spina bifida 22 | 1,064
Becker muscular dystrophy 21 | 187
dermatomyositis 21 | 933
fibroadenoma 21 | 557
Inflammatory bowel disease 20 | 142
Multiple Sclerosis 20 | 498
medulloblastoma 20 | 1,524

Tissue

Endocrine System 260 | 18,512
Female tissues 259 | 18,647
Nervous System 259 | 18,561
Urinary Tract 259 | 18,444
Digestive Tract 258 | 18,473
Skin and soft tissues 258 | 18,115
Cardiovascular System 255 | 17,958
Male tissues 254 | 17,969
Liver and Pancreas 253 | 18,136
Blood and immune system 251 | 17,995
Respiratory system 245 | 17,484

Target Family

Non-IDG 140 | 11,971
Transcription Factor 63 | 1,400
Kinase 28 | 634
Enzyme 24 | 4,146
Nuclear Receptor 4 | 48
GPCR 1 | 406
Ion Channel 1 | 341

Jensen-TM Tissue

Mesenchyme 261 | 261
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Fibronectin FN1 Tchem Non-IDG -3.04098 1121.3 1253
Alpha-fetoprotein AFP Tbio Non-IDG -4.04711 11505.1 1715