Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
decreased body weight 1 | 161
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 15 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 10 | 5,112
Cancer 9 | 2,499
glioblastoma 8 | 5,792
Breast cancer 7 | 3,578
group 3 medulloblastoma 7 | 4,104
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
medulloblastoma 6 | 720
medulloblastoma, large-cell 6 | 6,241
Abnormally small eyeball 5 | 97
Broad flat nasal bridge 5 | 236
Cleft Lip 5 | 141
Cleft Palate 5 | 271
Decreased size of eyeball 5 | 97
Epilepsy 5 | 792
Holoprosencephaly 5 | 56
Kidney cancer 5 | 2,613
Microphthalmos 5 | 100
Nasal bridge wide 5 | 236
Nevoid basal cell carcinoma syndrome 5 | 16
Polydactyly 5 | 107
Seizures 5 | 596
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
Basal cell carcinoma 4 | 54
Carcinoma, Basal Cell 4 | 28
Carcinoma, Hepatocellular 4 | 228
Cataract 4 | 297
Dull intelligence 4 | 645
Gastrointestinal Stromal Tumors 4 | 48
Highly variable severity 4 | 157
Intellectual disability 4 | 1,016
Lens Opacities 4 | 231
Liver carcinoma 4 | 240
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Strabismus 4 | 270
Variable expressivity 4 | 157
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Adenoma 3 | 167
Ameloblastoma 3 | 24
Anteverted nostril 3 | 191
Astrocytoma, Pilocytic 3 | 3,081
Big calvaria 3 | 147
Bladder Neoplasm 3 | 112
Cell Transformation, Neoplastic 3 | 97
Cognitive delay 3 | 608
Colonic Neoplasms 3 | 142
Congenital hemivertebra 3 | 25
Congenital hypoplasia of penis 3 | 176
Esophageal atresia 3 | 43
Frontal bossing 3 | 157
Glaucoma 3 | 239
Global developmental delay 3 | 608
Hydrocephalus 3 | 152
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Mental and motor retardation 3 | 608
Neoplastic Cell Transformation 3 | 89
Orbital separation excessive 3 | 244
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Panhypopituitarism 3 | 14
Parkinson's disease 3 | 392
Short 4th metacarpal 3 | 7
Short stature 3 | 531
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Uranostaphyloschisis 3 | 167
Urinary Bladder Neoplasms 3 | 114
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819
Colorectal Neoplasms 2 | 243
Cyclocephaly 2 | 4
Hypertrophic Cardiomyopathy 2 | 117
Hypoplasia or absence of the corpus callosum 2 | 23
Microglossia 2 | 10
Semilobar Holoprosencephaly 2 | 14
Small tongue 2 | 10
agnathia-otocephaly complex 2 | 8

Tissue

Endocrine System 17 | 18,159
Male tissues 17 | 17,142
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Cardiovascular System 14 | 15,192

Target Family

Transcription Factor 7 | 1,400
Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634

Jensen-TM Tissue

Medulloblastoma cell 17 | 17
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 Tchem Kinase -1.32729 19.5 234
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
Mediator of RNA polymerase II transcription subunit 27 MED27 Tbio Enzyme -1.49097 29.0 107
LINE-1 type transposase domain-containing protein 1 L1TD1 Tbio Enzyme -0.55122 5.22 51
DIS3-like exonuclease 1 DIS3L Tdark Enzyme -0.68418 3.89 94
Homeobox protein OTX2 OTX2 Tbio Transcription Factor -2.48486 317.0 248
N-myc proto-oncogene protein MYCN Tbio Transcription Factor -3.35747 2111.2 242
Cell division cycle-associated 7-like protein CDCA7L Tbio Non-IDG -1.12641 11.2 146
CREB/ATF bZIP transcription factor CREBZF Tbio Transcription Factor -0.98570 10.9 153
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705