Development Level

Tbio 150 | 10,625
Tchem 31 | 1,890
Tclin 23 | 602
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, incomple... 7 | 260
preweaning lethality, complete... 4 | 633
enlarged heart 3 | 111
abnormal behavior 2 | 226
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal coat-hair pigmentatio... 2 | 54
decreased body weight 2 | 174
decreased leukocyte cell numbe... 2 | 54
decreased monocyte cell number 2 | 28
embryonic lethality prior to t... 2 | 187
increased exploration in new e... 2 | 56
increased lean body mass 2 | 107
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
abnormal pancreas morphology 1 | 6
abnormal response to new envir... 1 | 8
abnormal seminal vesicle morph... 1 | 47
abnormal tail morphology 1 | 17
abnormal vitreous body morphol... 1 | 7
absent startle reflex 1 | 15
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged spleen 1 | 26
enlarged testis 1 | 1
herniated abdominal wall 1 | 4
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased anxiety-related resp... 1 | 1
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
premature death 1 | 5
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

Cancer 139 | 2,346
psoriasis 112 | 6,685
ovarian cancer 100 | 8,491
osteosarcoma 88 | 7,933
lung cancer 74 | 4,473
interstitial cystitis 69 | 2,299
lung carcinoma 65 | 2,844
medulloblastoma, large-cell 57 | 6,234
Breast cancer 51 | 3,098
malignant mesothelioma 50 | 3,163
non-small cell lung cancer 49 | 2,798
glioblastoma 48 | 5,572
cutaneous lupus erythematosus 47 | 1,056
invasive ductal carcinoma 47 | 2,950
ulcerative colitis 45 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
tuberculosis 42 | 1,563
Carcinoma 41 | 2,147
ductal carcinoma in situ 39 | 1,745
lung adenocarcinoma 39 | 2,714
pancreatic cancer 39 | 2,300
pilocytic astrocytoma 38 | 3,086
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
subependymal giant cell astrocytoma 33 | 2,287
pediatric high grade glioma 31 | 2,712
pituitary cancer 31 | 1,972
Rheumatoid Arthritis 30 | 1,170
Adenoma 29 | 165
nasopharyngeal carcinoma 28 | 1,056
primary Sjogren syndrome 28 | 788
breast carcinoma 27 | 1,614
diabetes mellitus 27 | 1,663
oligodendroglioma 27 | 2,849
Hypersensitivity reaction type II disease 26 | 235
cystic fibrosis 26 | 1,670
group 3 medulloblastoma 26 | 2,254
Multiple Sclerosis 25 | 498
colon cancer 23 | 1,475
group 4 medulloblastoma 23 | 1,875
primitive neuroectodermal tumor 22 | 3,031
Asthma 21 | 349
ependymoma 21 | 2,514
Stomach Neoplasms 20 | 282
adrenocortical carcinoma 20 | 1,427
adult high grade glioma 20 | 2,148
Mammary Neoplasms 19 | 410
Atopic dermatitis 18 | 944
Pick disease 18 | 1,893
astrocytoma 18 | 1,493
gastric carcinoma 18 | 832
Influenza 17 | 142
Prostatic Neoplasms 17 | 471
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
posterior fossa group A ependymoma 17 | 1,511
Endometriosis 16 | 535
juvenile dermatomyositis 16 | 1,189
Allergic hypersensitivity disease 15 | 123
Neoplasm Metastasis 15 | 138
head and neck cancer and chronic obstructive pulmonary disease 15 | 237
mucosa-associated lymphoid tissue lymphoma 15 | 480
primary pancreatic ductal adenocarcinoma 15 | 1,271
Inflammatory bowel disease 14 | 142
dermatomyositis 14 | 966
non-small cell lung carcinoma 14 | 413
Diarrhea 13 | 155
Human immunodeficiency virus infectious disease 13 | 129
astrocytic glioma 13 | 2,241
posterior fossa group B ependymoma 13 | 1,530
Dermatitis 12 | 141
Lupus erythematosus 12 | 80
active Crohn's disease 12 | 918
aldosterone-producing adenoma 12 | 664
sarcoidosis 12 | 368
Adenocarcinoma 11 | 115
Colorectal Neoplasms 11 | 217
Hepatitis B 11 | 103
Multiple myeloma 11 | 1,327
Neoplasm Invasiveness 11 | 127
medulloblastoma 11 | 1,524
sonic hedgehog group medulloblastoma 11 | 1,482
spina bifida 11 | 1,064
systemic lupus erythematosus 11 | 172
Animal Mammary Neoplasms 10 | 135
Celiac disease 10 | 112
Lung Neoplasms 10 | 171
Mammary Neoplasms, Experimental 10 | 149
Melanoma 10 | 261
Neutropenia 10 | 78
acute myeloid leukemia 10 | 785
acute quadriplegic myopathy 10 | 1,157
gastric cancer 10 | 436
hepatocellular carcinoma 10 | 550
inflammatory breast cancer 10 | 404
pancreatic carcinoma 10 | 567
Arthritis 9 | 248
Crohn's disease 9 | 304
chronic lymphosyte leukemia 9 | 232
esophageal adenocarcinoma 9 | 737

Tissue

Digestive Tract 203 | 18,472
Female tissues 203 | 18,646
Urinary Tract 202 | 18,443
Nervous System 201 | 18,560
Blood and immune system 200 | 17,994
Endocrine System 200 | 18,511
Skin and soft tissues 200 | 18,114
Cardiovascular System 198 | 17,957
Male tissues 198 | 17,968
Liver and Pancreas 196 | 18,135
Respiratory system 196 | 17,483

Target Family

Non-IDG 131 | 11,969
Enzyme 34 | 4,146
Transcription Factor 18 | 1,400
Kinase 9 | 634
GPCR 7 | 408
Transporter 3 | 473
Nuclear Receptor 2 | 48
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Lymph node 206 | 206
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.74239 5756.8 1322
Alpha-1-antichymotrypsin SERPINA3 Tchem Non-IDG -2.94207 803.8 261
GTPase KRas KRAS Tbio Enzyme -3.77389 5694.2 421
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.76199 528.6 688
CD82 antigen CD82 Tbio Non-IDG -2.60792 421.9 340
Protein S100-A4 S100A4 Tbio Non-IDG -2.74160 600.8 370