Development Level

Tbio 356 | 11,445
Tchem 192 | 1,598
Tclin 109 | 613
Tdark 6 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 35 | 979
preweaning lethality, incomple... 24 | 499
embryonic lethality prior to t... 18 | 278
enlarged heart 12 | 210
embryonic lethality prior to o... 11 | 239
increased total body fat amoun... 11 | 134
cataract 8 | 92
decreased vertical activity 8 | 208
increased circulating HDL chol... 8 | 80
increased circulating alkaline... 8 | 122
abnormal embryo size 7 | 220
abnormal heart morphology 7 | 162
decreased total body fat amoun... 7 | 207
male infertility 7 | 123
abnormal behavior 6 | 298
abnormal bone structure 6 | 187
abnormal lens morphology 6 | 81
decreased circulating insulin ... 6 | 76
decreased lean body mass 6 | 135
hyperactivity 6 | 148
increased circulating choleste... 6 | 66
increased startle reflex 6 | 112
small superior vagus ganglion 6 | 74
abnormal lung morphology 5 | 26
decreased body length 5 | 101
decreased body weight 5 | 161
decreased bone mineral content 5 | 151
decreased circulating triglyce... 5 | 79
embryonic growth retardation 5 | 106
impaired righting response 5 | 26
increased bone mineral content 5 | 108
increased circulating total pr... 5 | 28
short tibia 5 | 97
abnormal retinal blood vessel ... 4 | 26
abnormal retinal vasculature m... 4 | 27
abnormal seminal vesicle morph... 4 | 114
abnormal testis morphology 4 | 43
decreased circulating HDL chol... 4 | 68
decreased neutrophil cell numb... 4 | 42
edema 4 | 59
hydrometra 4 | 53
improved glucose tolerance 4 | 79
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 96
increased neutrophil cell numb... 4 | 46
prolonged ST segment 4 | 36
small testis 4 | 58
abnormal femur morphology 3 | 14
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
decreased blood urea nitrogen ... 3 | 51
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
decreased circulating creatini... 3 | 39
decreased circulating free fat... 3 | 31
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased erythrocyte cell num... 3 | 62
decreased hematocrit 3 | 46
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular vol... 3 | 79
female infertility 3 | 60
increased blood urea nitrogen ... 3 | 48
increased bone mineral density 3 | 72
increased circulating creatini... 3 | 38
increased circulating serum al... 3 | 22
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased spleen weight 3 | 10
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal cranium morphology 2 | 36
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal vertebrae morphology 2 | 18
abnormal vibrissa morphology 2 | 25
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating calcium ... 2 | 36
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased spleen weight 2 | 10
enlarged lymph nodes 2 | 37
enlarged uterus 2 | 11
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
increased body weight 2 | 25
increased circulating calcium ... 2 | 34
increased circulating triglyce... 2 | 42
increased eosinophil cell numb... 2 | 11
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
limb grasping 2 | 41
prolonged QT interval 2 | 38

Disease

Cancer 545 | 2,499
Carcinoma 426 | 11,493
ovarian cancer 371 | 8,520
psoriasis 371 | 6,694
lung cancer 346 | 4,740
osteosarcoma 311 | 7,950
glioblastoma 300 | 5,792
Breast cancer 244 | 3,578
lung carcinoma 239 | 2,843
medulloblastoma, large-cell 233 | 6,241
diabetes mellitus 227 | 1,728
non-small cell lung cancer 227 | 2,890
malignant mesothelioma 221 | 3,232
lung adenocarcinoma 220 | 2,716
ependymoma 218 | 4,679
pancreatic cancer 206 | 2,398
atypical teratoid / rhabdoid tumor 203 | 5,112
invasive ductal carcinoma 198 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 193 | 3,291
interstitial cystitis 189 | 2,312
ulcerative colitis 189 | 1,819
tuberculosis 185 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 183 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 180 | 2,989
adult high grade glioma 173 | 3,801
Astrocytoma, Pilocytic 172 | 3,081
Asthma 171 | 385
Kidney disease 169 | 430
cystic fibrosis 167 | 1,696
Hypertension 151 | 396
Schizophrenia 151 | 1,160
breast carcinoma 145 | 1,638
group 3 medulloblastoma 141 | 4,104
Arthritis 140 | 290
Breast Neoplasms 134 | 445
Mammary Neoplasms 133 | 425
Atherosclerosis 129 | 291
Vascular disease 128 | 319
Lung disease 127 | 142
Kidney cancer 124 | 2,613
ductal carcinoma in situ 124 | 1,745
oligodendroglioma 123 | 2,850
Heart disease 118 | 306
pituitary cancer 118 | 1,972
colon cancer 117 | 1,478
cutaneous lupus erythematosus 117 | 1,057
subependymal giant cell astrocytoma 116 | 2,287
Liver Cirrhosis, Experimental 115 | 769
Rheumatoid arthritis 114 | 1,191
primitive neuroectodermal tumor 114 | 3,035
Liver disease 111 | 237
Autosomal recessive predisposition 109 | 1,442
Obesity 109 | 678
Prostatic Neoplasms 109 | 495
Hypersensitivity reaction type II disease 108 | 253
adrenocortical carcinoma 107 | 1,428
nasopharyngeal carcinoma 105 | 1,058
Multiple Sclerosis 103 | 540
Coronary artery disease 102 | 268
pancreatic ductal adenocarcinoma liver metastasis 101 | 1,962
Inflammatory bowel disease 100 | 151
Cerebrovascular disease 98 | 238
astrocytic glioma 95 | 2,597
Atopic dermatitis 94 | 952
Hypertensive disease 94 | 292
Lung Neoplasms 94 | 232
Alzheimer's disease 92 | 658
primary pancreatic ductal adenocarcinoma 90 | 1,109
Stomach Neoplasms 88 | 300
Anemia 85 | 365
acute quadriplegic myopathy 83 | 1,158
juvenile dermatomyositis 83 | 1,187
gastric carcinoma 82 | 807
Carcinoma, Hepatocellular 80 | 228
Endometriosis 80 | 540
Liver carcinoma 80 | 240
Pneumonia 80 | 174
Bipolar Disorder 79 | 666
astrocytoma 79 | 1,146
Neoplasm Metastasis 78 | 168
group 4 medulloblastoma 77 | 1,855
Neoplasm Invasiveness 75 | 161
Depressive disorder 73 | 409
Multiple myeloma 73 | 1,332
Diarrhea 72 | 253
Dermatitis 71 | 157
Melanoma 71 | 711
esophageal adenocarcinoma 70 | 737
Adenoma 69 | 167
Allergic hypersensitivity disease 69 | 126
Pulmonary Fibrosis 69 | 106
active ulcerative colitis 67 | 764
Duchenne muscular dystrophy 65 | 601
active Crohn's disease 64 | 922
dermatomyositis 64 | 966
Epilepsy 63 | 792
Inflammation 62 | 120
Intellectual disability 60 | 1,016
non-small cell lung carcinoma 60 | 317
mucosa-associated lymphoid tissue lymphoma 59 | 484

Tissue

Endocrine System 639 | 18,159
Digestive Tract 637 | 17,369
Skin and soft tissues 636 | 17,230
Female tissues 633 | 17,400
Blood and immune system 630 | 16,909
Liver and Pancreas 630 | 16,750
Urinary Tract 626 | 16,678
Male tissues 625 | 17,142
Respiratory system 622 | 16,393
Nervous System 601 | 16,725
Cardiovascular System 555 | 15,192

Target Family

Non-IDG 336 | 12,091
Enzyme 150 | 4,145
Kinase 57 | 634
Transcription Factor 54 | 1,400
GPCR 29 | 408
Ion Channel 13 | 344
Transporter 11 | 473
Nuclear Receptor 7 | 48
Epigenetic 6 | 242

Jensen-TM Tissue

Lung 663 | 663
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Carcinoembryonic antigen-related cell adhesion molecule 6 CEACAM6 Tbio Non-IDG -2.41947 255.1 325
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439