Development Level

Tbio 288 | 10,625
Tchem 228 | 1,890
Tclin 99 | 602
Tdark 8 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 24 | 633
preweaning lethality, incomple... 16 | 260
embryonic lethality prior to t... 11 | 187
enlarged heart 9 | 111
decreased bone mineral content 8 | 157
decreased lean body mass 8 | 195
decreased grip strength 7 | 123
decreased body length 6 | 108
decreased circulating insulin ... 6 | 75
embryonic lethality prior to o... 6 | 148
increased circulating HDL chol... 6 | 63
increased circulating alkaline... 6 | 119
abnormal behavior 5 | 226
abnormal bone structure 5 | 131
abnormal embryo size 5 | 112
decreased body weight 5 | 174
increased total body fat amoun... 5 | 57
abnormal heart morphology 4 | 51
abnormal lens morphology 4 | 73
cataract 4 | 26
decreased blood urea nitrogen ... 4 | 31
decreased circulating triglyce... 4 | 83
decreased monocyte cell number 4 | 28
decreased total body fat amoun... 4 | 186
increased circulating choleste... 4 | 53
increased circulating triglyce... 4 | 24
increased mean corpuscular vol... 4 | 91
increased or absent threshold ... 4 | 128
male infertility 4 | 62
small testis 4 | 37
abnormal epididymis morphology 3 | 31
abnormal femur morphology 3 | 14
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal lung morphology 3 | 15
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
abnormal sleep behavior 3 | 63
abnormal snout morphology 3 | 18
abnormal testis morphology 3 | 30
decreased NK T cell number 3 | 28
decreased bone mineral density 3 | 126
decreased circulating LDL chol... 3 | 37
decreased circulating free fat... 3 | 39
decreased circulating glucose ... 3 | 121
decreased heart weight 3 | 44
enlarged epididymis 3 | 27
hydrops fetalis 3 | 22
impaired righting response 3 | 19
improved glucose tolerance 3 | 56
increased blood urea nitrogen ... 3 | 44
increased body weight 3 | 42
increased circulating potassiu... 3 | 31
increased circulating total pr... 3 | 20
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
short tibia 3 | 82
thrombocytopenia 3 | 46
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal coat/hair pigmentatio... 2 | 54
abnormal coping response 2 | 12
abnormal head morphology 2 | 10
abnormal retina morphology 2 | 100
abnormal spinal cord morpholog... 2 | 8
abnormal tooth morphology 2 | 24
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating calcium ... 2 | 33
decreased circulating creatini... 2 | 31
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased kidney weight 2 | 7
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular vol... 2 | 50
female infertility 2 | 34
hyperactivity 2 | 108
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
impaired pupillary reflex 2 | 14
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating LDL chol... 2 | 15
increased circulating creatini... 2 | 29
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 25
increased respiratory quotient 2 | 12
increased sacral vertebrae num... 2 | 62
increased spleen weight 2 | 3
limb grasping 2 | 35
narrow eye opening 2 | 15
premature death 2 | 5
tremors 2 | 34
abnormal tail movements 1 | 12
decreased circulating magnesiu... 1 | 11
decreased mean corpuscular hem... 1 | 34
increased NK cell number 1 | 19

Disease

Cancer 504 | 2,346
psoriasis 342 | 6,685
ovarian cancer 339 | 8,484
lung cancer 318 | 4,466
osteosarcoma 289 | 7,933
glioblastoma 265 | 5,572
lung carcinoma 232 | 2,844
ulcerative colitis 213 | 2,087
medulloblastoma, large-cell 210 | 6,234
lung adenocarcinoma 208 | 2,713
non-small cell lung cancer 207 | 2,798
diabetes mellitus 204 | 1,663
Breast cancer 195 | 3,094
pancreatic cancer 190 | 2,300
malignant mesothelioma 189 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 186 | 3,289
invasive ductal carcinoma 186 | 2,950
interstitial cystitis 178 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 171 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 170 | 2,956
pilocytic astrocytoma 166 | 3,086
atypical teratoid / rhabdoid tumor 165 | 4,369
Asthma 164 | 349
Kidney disease 162 | 396
cystic fibrosis 161 | 1,665
tuberculosis 159 | 1,557
pediatric high grade glioma 143 | 2,712
Arthritis 126 | 248
Mammary Neoplasms 124 | 410
breast carcinoma 123 | 1,614
Atherosclerosis 122 | 275
Vascular disease 121 | 281
ductal carcinoma in situ 121 | 1,745
Carcinoma 119 | 2,147
Lung disease 119 | 132
Hypertension 116 | 287
oligodendroglioma 115 | 2,849
pituitary cancer 115 | 1,972
cutaneous lupus erythematosus 112 | 1,056
Rheumatoid Arthritis 110 | 1,160
Heart disease 109 | 279
subependymal giant cell astrocytoma 109 | 2,287
primitive neuroectodermal tumor 108 | 3,031
colon cancer 107 | 1,475
Prostatic Neoplasms 102 | 471
posterior fossa group A ependymoma 102 | 1,511
Obesity 101 | 616
adrenocortical carcinoma 100 | 1,427
Liver disease 99 | 219
nasopharyngeal carcinoma 99 | 1,056
primary pancreatic ductal adenocarcinoma 99 | 1,271
Hypersensitivity reaction type II disease 98 | 235
Cerebrovascular disease 95 | 231
Inflammatory bowel disease 95 | 142
Multiple Sclerosis 95 | 498
astrocytoma 89 | 1,493
ependymoma 88 | 2,514
Coronary artery disease 87 | 240
Atopic dermatitis 86 | 944
Lung Neoplasms 84 | 171
pancreatic ductal adenocarcinoma liver metastasis 82 | 1,795
gastric carcinoma 80 | 832
Endometriosis 79 | 535
Alzheimer's disease 78 | 644
Stomach Neoplasms 78 | 282
group 3 medulloblastoma 78 | 2,254
juvenile dermatomyositis 78 | 1,189
acute quadriplegic myopathy 77 | 1,157
adult high grade glioma 77 | 2,148
Liver carcinoma 73 | 217
Pneumonia 72 | 133
group 4 medulloblastoma 72 | 1,875
Adenoma 69 | 165
Multiple myeloma 69 | 1,327
astrocytic glioma 68 | 2,241
Anemia 67 | 252
non-small cell lung carcinoma 67 | 413
Dermatitis 65 | 107
Neoplasm Metastasis 65 | 138
Allergic hypersensitivity disease 64 | 123
esophageal adenocarcinoma 64 | 737
Hypertensive disease 62 | 193
active Crohn's disease 61 | 918
primary Sjogren syndrome 61 | 789
Neoplasm Invasiveness 60 | 127
Diarrhea 57 | 155
Duchenne muscular dystrophy 57 | 602
Inflammation 57 | 109
mucosa-associated lymphoid tissue lymphoma 57 | 480
dermatomyositis 55 | 933
sonic hedgehog group medulloblastoma 55 | 1,482
Reperfusion Injury 54 | 84
medulloblastoma 54 | 1,524
Down syndrome 53 | 548
posterior fossa group B ependymoma 53 | 1,530
Colorectal Neoplasms 52 | 217
Myocardial Ischemia 51 | 169
Peripheral Neuropathy 51 | 303
Schizophrenia 51 | 501
Toxic encephalopathy 51 | 131

Tissue

Digestive Tract 611 | 18,473
Nervous System 610 | 18,561
Urinary Tract 610 | 18,444
Female tissues 609 | 18,647
Endocrine System 608 | 18,512
Blood and immune system 603 | 17,995
Liver and Pancreas 603 | 18,136
Skin and soft tissues 603 | 18,115
Respiratory system 602 | 17,484
Cardiovascular System 598 | 17,958
Male tissues 594 | 17,969

Target Family

Non-IDG 321 | 11,971
Enzyme 142 | 4,146
Transcription Factor 51 | 1,400
Kinase 50 | 634
GPCR 27 | 406
Transporter 11 | 473
Ion Channel 9 | 341
Epigenetic 6 | 242
Nuclear Receptor 6 | 48

Jensen-TM Tissue

Lung 623 | 623
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682