Development Level

Tbio 519 | 10,625
Tchem 347 | 1,890
Tclin 119 | 602
Tdark 16 | 7,003

IMPC Term

preweaning lethality, complete... 39 | 633
preweaning lethality, incomple... 20 | 260
embryonic lethality prior to t... 18 | 187
abnormal behavior 16 | 226
decreased total body fat amoun... 15 | 186
decreased lean body mass 12 | 195
decreased bone mineral content 11 | 157
embryonic lethality prior to o... 11 | 148
increased circulating choleste... 11 | 53
decreased body weight 10 | 174
decreased bone mineral density 10 | 126
decreased circulating choleste... 10 | 85
decreased grip strength 10 | 123
increased circulating alkaline... 10 | 119
hypoactivity 9 | 89
increased circulating HDL chol... 9 | 63
abnormal embryo size 8 | 112
abnormal lens morphology 8 | 73
abnormal retina morphology 8 | 100
decreased circulating HDL chol... 8 | 77
hyperactivity 8 | 108
increased grip strength 8 | 83
increased mean corpuscular vol... 8 | 91
increased or absent threshold ... 8 | 128
short tibia 8 | 82
abnormal bone mineralization 7 | 55
abnormal bone structure 7 | 131
decreased body length 7 | 108
decreased circulating insulin ... 7 | 75
decreased circulating triglyce... 7 | 83
enlarged heart 7 | 111
increased lean body mass 7 | 107
decreased circulating LDL chol... 6 | 37
decreased circulating glucose ... 6 | 121
increased body weight 6 | 42
increased circulating triglyce... 6 | 24
increased mean corpuscular hem... 6 | 93
increased total body fat amoun... 6 | 57
abnormal epididymis morphology 5 | 31
abnormal sleep behavior 5 | 63
abnormal testis morphology 5 | 30
cataract 5 | 26
decreased circulating alanine ... 5 | 53
decreased circulating creatini... 5 | 31
decreased heart weight 5 | 44
decreased hemoglobin content 5 | 53
enlarged epididymis 5 | 27
improved glucose tolerance 5 | 56
increased circulating alanine ... 5 | 11
small testis 5 | 37
thrombocytopenia 5 | 46
abnormal gait 4 | 51
abnormal hindbrain development 4 | 24
abnormal neural tube closure 4 | 37
abnormal retinal pigmentation 4 | 61
decreased T cell number 4 | 31
decreased circulating aspartat... 4 | 27
decreased circulating calcium ... 4 | 33
decreased lactate dehydrogenas... 4 | 14
decreased mean corpuscular hem... 4 | 34
decreased mean corpuscular vol... 4 | 50
decreased monocyte cell number 4 | 28
decreased prepulse inhibition 4 | 52
increased blood urea nitrogen ... 4 | 44
increased circulating bilirubi... 4 | 16
increased circulating creatini... 4 | 29
increased circulating potassiu... 4 | 31
increased circulating serum al... 4 | 25
increased exploration in new e... 4 | 56
increased fasted circulating g... 4 | 68
increased hematocrit 4 | 36
male infertility 4 | 62
tremors 4 | 34
abnormal coat/hair pigmentatio... 3 | 54
abnormal femur morphology 3 | 14
abnormal heart left ventricle ... 3 | 20
abnormal heart morphology 3 | 51
abnormal midbrain development 3 | 22
abnormal respiratory quotient 3 | 9
abnormal seminal vesicle morph... 3 | 47
abnormal skin morphology 3 | 23
abnormal snout morphology 3 | 18
abnormal tooth morphology 3 | 24
abnormal vibrissa morphology 3 | 17
decreased blood urea nitrogen ... 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating alkaline... 3 | 41
decreased circulating chloride... 3 | 32
decreased circulating free fat... 3 | 39
decreased circulating serum al... 3 | 79
decreased fasted circulating g... 3 | 49
decreased spleen weight 3 | 13
enlarged spleen 3 | 26
impaired glucose tolerance 3 | 52
increased circulating aspartat... 3 | 17
increased circulating sodium l... 3 | 71
increased hemoglobin content 3 | 45
increased startle reflex 3 | 38
limb grasping 3 | 35
straub tail 3 | 26

Disease

Cancer 594 | 2,346
ovarian cancer 527 | 8,484
psoriasis 510 | 6,685
osteosarcoma 422 | 7,933
lung cancer 397 | 4,466
glioblastoma 352 | 5,572
diabetes mellitus 336 | 1,663
medulloblastoma, large-cell 330 | 6,234
malignant mesothelioma 284 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 274 | 3,289
lung carcinoma 268 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 265 | 2,956
invasive ductal carcinoma 257 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 253 | 1,795
intraductal papillary-mucinous carcinoma (IPMC) 248 | 2,988
lung adenocarcinoma 244 | 2,713
ulcerative colitis 240 | 2,087
non-small cell lung cancer 239 | 2,798
pancreatic cancer 239 | 2,300
Obesity 231 | 616
Breast cancer 229 | 3,094
atypical teratoid / rhabdoid tumor 224 | 4,369
interstitial cystitis 209 | 2,299
pilocytic astrocytoma 197 | 3,086
tuberculosis 185 | 1,557
Kidney disease 184 | 396
pediatric high grade glioma 175 | 2,712
ductal carcinoma in situ 172 | 1,745
Liver disease 170 | 219
breast carcinoma 167 | 1,614
pituitary cancer 162 | 1,972
Atherosclerosis 158 | 275
primitive neuroectodermal tumor 155 | 3,031
cystic fibrosis 154 | 1,665
oligodendroglioma 147 | 2,849
adrenocortical carcinoma 145 | 1,427
Vascular disease 144 | 281
Rheumatoid Arthritis 143 | 1,160
subependymal giant cell astrocytoma 143 | 2,287
Prostatic Neoplasms 142 | 471
colon cancer 142 | 1,475
Mammary Neoplasms 137 | 410
Carcinoma 130 | 2,147
astrocytoma 129 | 1,493
Coronary artery disease 126 | 240
Hypertension 126 | 287
ependymoma 125 | 2,514
Anemia 123 | 252
Heart disease 118 | 279
primary pancreatic ductal adenocarcinoma 117 | 1,271
acute quadriplegic myopathy 116 | 1,157
posterior fossa group A ependymoma 115 | 1,511
Metabolic syndrome X 114 | 155
Multiple myeloma 114 | 1,327
cutaneous lupus erythematosus 114 | 1,056
group 4 medulloblastoma 114 | 1,875
Atopic dermatitis 113 | 944
Liver carcinoma 110 | 217
Arthritis 109 | 248
Alzheimer's disease 108 | 644
adult high grade glioma 108 | 2,148
Cerebrovascular disease 103 | 231
group 3 medulloblastoma 102 | 2,254
Asthma 100 | 349
active Crohn's disease 98 | 918
Hypersensitivity reaction type II disease 97 | 235
juvenile dermatomyositis 95 | 1,189
Multiple Sclerosis 93 | 498
astrocytic glioma 93 | 2,241
dermatomyositis 93 | 933
Lung disease 90 | 132
gastric carcinoma 90 | 832
nasopharyngeal carcinoma 89 | 1,056
Hyperglycemia 86 | 120
Endometriosis 85 | 535
Lung Neoplasms 85 | 171
medulloblastoma 85 | 1,524
esophageal adenocarcinoma 84 | 737
Inflammatory bowel disease 82 | 142
Drug-Induced Liver Injury 81 | 118
Stomach Neoplasms 80 | 282
Adenoma 77 | 165
Liver Cirrhosis, Experimental 76 | 108
posterior fossa group B ependymoma 76 | 1,530
Hypertensive disease 75 | 193
Pick disease 75 | 1,893
Duchenne muscular dystrophy 74 | 602
Fatty liver disease 74 | 84
Lipid metabolism disorder 74 | 102
Cholestasis 73 | 93
Colorectal Neoplasms 71 | 217
Peripheral Neuropathy 71 | 303
aldosterone-producing adenoma 70 | 664
Diarrhea 69 | 155
Waldenstrons macroglobulinemia 69 | 765
sonic hedgehog group medulloblastoma 69 | 1,482
Neoplasm Metastasis 68 | 138
non-small cell lung carcinoma 68 | 413
Down syndrome 67 | 548
primary Sjogren syndrome 67 | 789

Tissue

Digestive Tract 986 | 18,473
Liver and Pancreas 982 | 18,136
Nervous System 982 | 18,561
Female tissues 981 | 18,647
Urinary Tract 981 | 18,444
Endocrine System 979 | 18,512
Blood and immune system 977 | 17,995
Skin and soft tissues 971 | 18,115
Male tissues 961 | 17,969
Cardiovascular System 959 | 17,958
Respiratory system 956 | 17,484

Target Family

Non-IDG 409 | 11,971
Enzyme 377 | 4,146
Transcription Factor 71 | 1,400
Kinase 59 | 634
Transporter 42 | 473
Nuclear Receptor 19 | 48
GPCR 11 | 406
Epigenetic 8 | 242
Ion Channel 3 | 341
TF/Epigenetic 2 | 38

Jensen-TM Tissue

Liver 1,001 | 1,001
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851