Development Level

Tbio 33 | 11,445
Tdark 8 | 6,588
Tchem 4 | 1,598
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 2 | 161
impaired pupillary reflex 2 | 26
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
decreased B cell number 1 | 5
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 30 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 18 | 7,950
psoriasis 14 | 6,694
lung cancer 12 | 4,740
diabetes mellitus 11 | 1,728
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 10 | 6,241
ependymoma 9 | 4,679
glioblastoma 8 | 5,792
Cerebellar Ataxia 7 | 304
Optic Atrophy 7 | 242
atypical teratoid / rhabdoid tumor 7 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Abnormal vision 6 | 52
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Autosomal recessive predisposition 5 | 1,442
Cardiac Arrhythmia 5 | 103
Cardiac conduction abnormalities 5 | 78
Conduction disorder of the heart 5 | 79
Dementia 5 | 175
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Highly variable severity 5 | 157
Intellectual disability 5 | 1,016
Mitochondrial Myopathies 5 | 21
Multiple myeloma 5 | 1,332
Myopathy 5 | 185
Sensorineural Hearing Loss (disorder) 5 | 284
Short stature 5 | 531
Variable expressivity 5 | 157
astrocytic glioma 5 | 2,597
Acidosis, Lactic 4 | 97
Anorexia 4 | 43
Attention deficit hyperactivity disorder 4 | 278
Blepharoptosis 4 | 231
Blind spot located at fixation point 4 | 21
Blindness, Cortical 4 | 24
Cerebral atrophy 4 | 178
Clonus 4 | 18
Cognitive delay 4 | 608
Congenital Bilateral Cataracts 4 | 50
Congenital cataract 4 | 50
Congestive heart failure 4 | 113
Cortical visual impairment 4 | 24
Decreased visual acuity, slowly progressive 4 | 13
Developmental regression 4 | 95
Dystonia 4 | 164
Dystonic disease 4 | 106
Encephalopathies 4 | 43
Epilepsy 4 | 792
Episodic vomiting 4 | 10
Frequent vomiting 4 | 10
Heart failure 4 | 162
Hemianopsia 4 | 15
Hemiparesis 4 | 34
Intermittent migraine headaches 4 | 68
Lactic acidemia 4 | 95
Lactic acidosis 4 | 51
Leber hereditary optic neuropathy 4 | 14
Left Ventricular Hypertrophy 4 | 47
Leigh disease 4 | 100
Loss of developmental milestones 4 | 95
Mental and motor retardation 4 | 608
Mental deterioration in childhood 4 | 95
Migraine Disorders 4 | 76
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 4 | 9
Mitochondrial respiratory chain defects 4 | 15
Muscle Weakness 4 | 170
Neurodevelopmental regression 4 | 95
Ophthalmoplegia 4 | 106
Optic Neuropathy 4 | 12
Pancreatitis 4 | 123
Peripheral Neuropathy 4 | 134
Polyneuropathy 4 | 64
Psychomotor regression 4 | 95
Psychomotor regression beginning in infancy 4 | 95
Psychomotor regression in infants 4 | 95
Psychomotor regression, progressive 4 | 95
Ragged-red fibers 4 | 21
Respiratory Insufficiency 4 | 132
Respiratory function loss 4 | 121
Retinal telangiectasia 4 | 12
Scotoma, Central 4 | 21
Seizures 4 | 596
Sensorineural hearing loss, bilateral 4 | 18
Sleeping sickness 4 | 37
Slow decrease in visual acuity 4 | 13
Static Tremor 4 | 21
Tonic - clonic seizures 4 | 44
Wolff-Parkinson-White syndrome 4 | 19
abnormal growth 4 | 26
adult high grade glioma 4 | 3,801
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
primitive neuroectodermal tumor 4 | 3,035

Tissue

Blood and immune system 49 | 16,909
Endocrine System 49 | 18,159
Nervous System 49 | 16,725
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Cardiovascular System 47 | 15,192
Digestive Tract 47 | 17,369
Respiratory system 47 | 16,393

Target Family

Enzyme 23 | 4,145
Non-IDG 19 | 12,091
Kinase 3 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Transporter 1 | 473

Jensen-TM Tissue

Kinetoplastid 49 | 49
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 3-beta-1 TOP3B Tbio Enzyme -1.06981 9.54 153
Peroxisomal membrane protein 4 PXMP4 Tdark Non-IDG -0.51334 4.00 99
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 Tclin Enzyme -0.62794 3.79 65
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
Tubulin delta chain TUBD1 Tbio Non-IDG -1.28681 18.5 57
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 Tbio Enzyme -1.13540 12.8 55
O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS Tbio Enzyme -2.11362 120.5 120
Tripartite motif-containing protein 54 TRIM54 Tbio Non-IDG -1.55520 36.7 243
ADP-ribosylation factor-like protein 1 ARL1 Tbio Enzyme -0.41493 3.54 208
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134