Development Level

Tbio 530 | 11,651
Tchem 211 | 1,388
Tclin 134 | 612
Tdark 13 | 6,593

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 54 | 979
preweaning lethality, incomple... 31 | 499
embryonic lethality prior to t... 21 | 278
abnormal behavior 16 | 298
embryonic lethality prior to o... 16 | 239
enlarged heart 16 | 210
abnormal bone structure 14 | 187
abnormal embryo size 13 | 220
hypoactivity 13 | 132
abnormal heart morphology 12 | 162
decreased bone mineral content 12 | 151
decreased vertical activity 12 | 208
increased total body fat amoun... 12 | 134
decreased total body fat amoun... 10 | 207
increased circulating HDL chol... 10 | 80
increased circulating alkaline... 10 | 122
increased startle reflex 10 | 112
abnormal seminal vesicle morph... 9 | 114
embryonic growth retardation 9 | 106
abnormal retina morphology 8 | 71
decreased body weight 8 | 161
decreased circulating HDL chol... 8 | 68
decreased circulating triglyce... 8 | 79
increased circulating choleste... 8 | 66
increased lean body mass 8 | 172
abnormal lens morphology 7 | 81
cataract 7 | 92
decreased body length 7 | 101
decreased circulating choleste... 7 | 93
decreased circulating insulin ... 7 | 76
increased circulating creatini... 7 | 38
prolonged ST segment 7 | 36
decreased erythrocyte cell num... 6 | 62
decreased grip strength 6 | 116
decreased lean body mass 6 | 135
decreased mean corpuscular vol... 6 | 79
hyperactivity 6 | 148
increased blood urea nitrogen ... 6 | 48
increased circulating sodium l... 6 | 71
increased heart weight 6 | 62
increased mean corpuscular vol... 6 | 92
prolonged QT interval 6 | 38
short tibia 6 | 97
small superior vagus ganglion 6 | 74
abnormal gait 5 | 69
abnormal testis morphology 5 | 43
decreased circulating LDL chol... 5 | 38
decreased circulating amylase ... 5 | 28
decreased circulating calcium ... 5 | 36
decreased circulating creatini... 5 | 39
decreased circulating glucose ... 5 | 126
decreased circulating phosphat... 5 | 27
decreased circulating serum al... 5 | 82
decreased hemoglobin content 5 | 68
decreased prepulse inhibition 5 | 82
impaired glucose tolerance 5 | 75
increased bone mineral content 5 | 108
increased lymphocyte cell numb... 5 | 32
increased neutrophil cell numb... 5 | 46
male infertility 5 | 123
small testis 5 | 58
thrombocytopenia 5 | 56
abnormal femur morphology 4 | 14
abnormal kidney morphology 4 | 65
abnormal lung morphology 4 | 26
abnormal vertebrae morphology 4 | 18
decreased bone mineral density 4 | 126
decreased circulating bilirubi... 4 | 19
decreased fasted circulating g... 4 | 65
decreased lymphocyte cell numb... 4 | 83
enlarged uterus 4 | 11
improved glucose tolerance 4 | 79
increased circulating bilirubi... 4 | 16
increased circulating calcium ... 4 | 34
increased circulating chloride... 4 | 41
increased circulating potassiu... 4 | 29
increased circulating total pr... 4 | 28
increased mean corpuscular hem... 4 | 96
abnormal bone mineralization 3 | 38
abnormal cranium morphology 3 | 36
abnormal neural tube closure 3 | 46
abnormal sleep behavior 3 | 70
abnormal spleen morphology 3 | 55
abnormal vibrissa morphology 3 | 25
abnormal vocalization 3 | 21
decreased circulating alkaline... 3 | 46
decreased circulating aspartat... 3 | 34
decreased circulating total pr... 3 | 49
decreased neutrophil cell numb... 3 | 42
decreased red blood cell distr... 3 | 41
decreased startle reflex 3 | 75
enlarged lymph nodes 3 | 37
enlarged spleen 3 | 41
hydrometra 3 | 53
impaired righting response 3 | 26
increased circulating serum al... 3 | 22
increased circulating triglyce... 3 | 42
increased monocyte cell number 3 | 63
persistence of hyaloid vascula... 3 | 33
tremors 3 | 39

Disease

Carcinoma 589 | 11,493
Cancer 553 | 2,499
ovarian cancer 442 | 8,520
psoriasis 436 | 6,694
osteosarcoma 362 | 7,950
diabetes mellitus 346 | 1,728
lung cancer 343 | 4,740
glioblastoma 329 | 5,792
Kidney disease 325 | 430
medulloblastoma, large-cell 280 | 6,241
malignant mesothelioma 257 | 3,232
ependymoma 247 | 4,679
atypical teratoid / rhabdoid tumor 241 | 5,112
Hypertension 232 | 396
lung carcinoma 232 | 2,843
Breast cancer 224 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 216 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 211 | 2,955
lung adenocarcinoma 211 | 2,716
non-small cell lung cancer 208 | 2,890
pancreatic cancer 206 | 2,398
adult high grade glioma 203 | 3,801
invasive ductal carcinoma 202 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 189 | 2,989
tuberculosis 188 | 2,010
Astrocytoma, Pilocytic 185 | 3,081
Autosomal recessive predisposition 183 | 1,442
Schizophrenia 175 | 1,160
ulcerative colitis 175 | 1,819
interstitial cystitis 174 | 2,312
group 3 medulloblastoma 173 | 4,104
Arthritis 170 | 290
cystic fibrosis 170 | 1,696
Kidney cancer 165 | 2,613
Rheumatoid arthritis 160 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 157 | 1,962
Obesity 155 | 678
Liver disease 147 | 237
Hypersensitivity reaction type II disease 146 | 253
oligodendroglioma 144 | 2,850
Vascular disease 143 | 319
Heart disease 142 | 306
subependymal giant cell astrocytoma 141 | 2,287
Hypertensive disease 136 | 292
Atherosclerosis 134 | 291
Anemia 131 | 365
Liver Cirrhosis, Experimental 131 | 769
ductal carcinoma in situ 131 | 1,745
pituitary cancer 129 | 1,972
breast carcinoma 126 | 1,638
primitive neuroectodermal tumor 123 | 3,035
Alzheimer's disease 120 | 658
colon cancer 120 | 1,478
Cerebrovascular disease 119 | 238
Coronary artery disease 116 | 268
astrocytic glioma 115 | 2,597
Multiple Sclerosis 114 | 540
Prostatic Neoplasms 113 | 495
adrenocortical carcinoma 113 | 1,428
dermatomyositis 109 | 966
Breast Neoplasms 108 | 445
cutaneous lupus erythematosus 108 | 1,057
Mammary Neoplasms 105 | 425
Epilepsy 101 | 792
group 4 medulloblastoma 100 | 1,855
Asthma 99 | 385
astrocytoma 97 | 1,146
Diarrhea 95 | 253
Pick disease 90 | 1,894
Bipolar Disorder 89 | 666
Lung disease 89 | 142
primary pancreatic ductal adenocarcinoma 89 | 1,109
Acquired immunodeficiency syndrome 88 | 197
Multiple myeloma 88 | 1,332
Intellectual disability 87 | 1,016
acute quadriplegic myopathy 87 | 1,158
juvenile dermatomyositis 87 | 1,187
Seizures 84 | 596
gastric carcinoma 84 | 807
Depressive disorder 83 | 409
Dermatitis 83 | 157
Melanoma 83 | 711
Uveitis 82 | 103
Osteoporosis 81 | 363
Inflammatory bowel disease 80 | 151
Hyperglycemia 77 | 137
Dull intelligence 75 | 645
Endometriosis 75 | 540
Low intelligence 75 | 645
Mental Retardation 75 | 645
Mental deficiency 75 | 645
Poor school performance 75 | 645
Ankylosing spondylitis 74 | 140
Liver carcinoma 73 | 240
Major Depressive Disorder 73 | 301
Short stature 73 | 531
Stomach Neoplasms 72 | 300
active Crohn's disease 72 | 922
esophageal adenocarcinoma 71 | 737
nephrosclerosis 71 | 333

Tissue

Endocrine System 793 | 18,159
Digestive Tract 792 | 17,369
Urinary Tract 791 | 16,678
Liver and Pancreas 781 | 16,750
Skin and soft tissues 781 | 17,230
Female tissues 779 | 17,400
Male tissues 779 | 17,142
Blood and immune system 761 | 16,909
Nervous System 755 | 16,725
Respiratory system 744 | 16,393
Cardiovascular System 673 | 15,192

Target Family

Non-IDG 434 | 12,091
Enzyme 201 | 4,145
Transporter 80 | 473
Kinase 54 | 634
Transcription Factor 43 | 1,400
Ion Channel 33 | 344
GPCR 27 | 408
Nuclear Receptor 11 | 48
Epigenetic 5 | 242

Jensen-TM Tissue

Kidney 888 | 888
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Tbio Kinase -2.11714 148.9 575
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
Dual oxidase 2 DUOX2 Tbio Enzyme -2.45061 251.8 126