Development Level

Tbio 28 | 11,445
Tdark 5 | 6,588
Tchem 3 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

absent startle reflex 3 | 24
decreased circulating triglyce... 3 | 79
hyperactivity 3 | 148
increased or absent threshold ... 3 | 101
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
preweaning lethality, complete... 2 | 979
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
head bobbing 1 | 5
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased vertical activity 1 | 24
mammalian phenotype 1 | 17
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 32 | 11,493
psoriasis 19 | 6,694
osteosarcoma 17 | 7,950
ovarian cancer 17 | 8,520
medulloblastoma, large-cell 16 | 6,241
Nonsyndromic deafness 15 | 142
atypical teratoid / rhabdoid tumor 15 | 5,112
adult high grade glioma 14 | 3,801
ependymoma 14 | 4,679
glioblastoma 14 | 5,792
group 3 medulloblastoma 14 | 4,104
Astrocytoma, Pilocytic 12 | 3,081
Sensorineural hearing loss 12 | 106
primitive neuroectodermal tumor 12 | 3,035
Breast cancer 10 | 3,578
malignant mesothelioma 10 | 3,232
oligodendroglioma 10 | 2,850
Pick disease 9 | 1,894
lung cancer 9 | 4,740
subependymal giant cell astrocytoma 9 | 2,287
Kidney cancer 8 | 2,613
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung carcinoma 8 | 2,843
pituitary cancer 8 | 1,972
Deafness 7 | 198
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Autosomal recessive predisposition 6 | 1,442
cystic fibrosis 6 | 1,696
Bipolar Disorder 5 | 666
Hodgkin's lymphoma, nodular sclerosis 5 | 22
Schizophrenia 5 | 1,160
ductal carcinoma in situ 5 | 1,745
hearing impairment 5 | 199
non-small cell lung cancer 5 | 2,890
Congenital deafness 4 | 185
Epilepsy 4 | 792
Hearing Loss, Partial 4 | 185
Liver cancer 4 | 604
Neuropathy 4 | 261
Parkinson's disease 4 | 392
Retinitis Pigmentosa 4 | 226
Usher syndrome 4 | 32
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Blindness 3 | 88
Cataract 3 | 297
Down syndrome 3 | 499
Glaucoma 3 | 239
Lens Opacities 3 | 231
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Neurodegenerative disease 3 | 414
Night Blindness 3 | 101
Toxic encephalopathy 3 | 141
aldosterone-producing adenoma 3 | 665
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819
Asthma 2 | 385
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Blepharoptosis 2 | 231
Botulism 2 | 24
Cancer 2 | 2,499
Congenital stationary night blindness 2 | 29
Difficulties with night vision 2 | 87
Hypertension 2 | 396
Low Vision 2 | 174
Major Depressive Disorder 2 | 301
Nerve Degeneration 2 | 121
Panic disorder 2 | 61
Pigmentary iris degeneration 2 | 20
Retinal blind spot 2 | 11
Rheumatoid arthritis 2 | 1,191
Scotoma 2 | 22
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Spastic Paraplegia 2 | 42
Status Epilepticus 2 | 98
Tonic-clonic epilepsy 2 | 47
Unipolar Depression 2 | 250
Visual Impairment 2 | 174
adrenocortical carcinoma 2 | 1,428
fibroadenoma 2 | 559
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
posterior fossa group A ependymoma 2 | 468
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074

Tissue

Digestive Tract 37 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Nervous System 36 | 16,725
Skin and soft tissues 35 | 17,230
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Urinary Tract 34 | 16,678
Blood and immune system 31 | 16,909
Respiratory system 29 | 16,393
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 24 | 12,091
Ion Channel 6 | 344
Transporter 5 | 473
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

Jensen-TM Tissue

Inner hair cell 38 | 38
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Regulating synaptic membrane exocytosis protein 3 RIMS3 Tbio Non-IDG -1.28577 18.9 75
Synaptotagmin-2 SYT2 Tbio Non-IDG -1.93503 86.7 222
Pejvakin PJVK Tbio Non-IDG -1.15873 16.2 55
Protein bassoon BSN Tbio Non-IDG -3.05805 1116.2 84
Phospholipase B-like 1 PLBD1 Tdark Enzyme -0.34063 2.15 52
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.14434 12.3 108
Transmembrane protein 132E TMEM132E Tdark Non-IDG -0.21085 1.74 58
Transmembrane channel-like protein 3 TMC3 Tbio Ion Channel -0.23709 1.61 11
C-terminal-binding protein 2 CTBP2 Tchem Non-IDG -2.63977 410.7 251