Development Level

Tbio 45 | 11,651
Tchem 8 | 1,388
Tclin 3 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal lens morphology 3 | 81
cataract 3 | 92
corneal opacity 3 | 32
decreased lean body mass 3 | 135
improved glucose tolerance 3 | 79
increased total body fat amoun... 3 | 134
narrow eye opening 3 | 12
abnormal behavior 2 | 298
abnormal optic disc morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal vitreous body morphol... 2 | 10
absent startle reflex 2 | 24
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
fused cornea and lens 2 | 5
impaired pupillary reflex 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
iris synechia 2 | 3
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal iris transilluminatio... 1 | 2
abnormal kidney morphology 1 | 65
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spine curvature 1 | 9
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cleft palate 1 | 8
cornea ulcer 1 | 1
cyanosis 1 | 7
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating phosphat... 1 | 26
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
long tibia 1 | 25
mammalian phenotype 1 | 17
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
short tibia 1 | 97
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 33 | 11,493
ovarian cancer 31 | 8,520
Cancer 25 | 2,499
psoriasis 23 | 6,694
lung cancer 20 | 4,740
medulloblastoma, large-cell 19 | 6,241
osteosarcoma 18 | 7,950
glioblastoma 17 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Tooth agenesis 15 | 44
atypical teratoid / rhabdoid tumor 15 | 5,112
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
Breast cancer 14 | 3,578
Cleft Lip 14 | 141
Cleft Palate 14 | 271
Autosomal recessive predisposition 13 | 1,442
group 3 medulloblastoma 13 | 4,104
invasive ductal carcinoma 13 | 2,951
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 12 | 2,890
lung adenocarcinoma 11 | 2,716
Astrocytoma, Pilocytic 10 | 3,081
adrenocortical carcinoma 10 | 1,428
adult high grade glioma 10 | 3,801
oligodendroglioma 10 | 2,850
pancreatic cancer 10 | 2,398
Amelogenesis imperfecta 9 | 29
Craniofacial Abnormalities 9 | 151
Dental caries 9 | 164
Dentin dysplasia 9 | 19
Osteoporosis 9 | 363
astrocytic glioma 9 | 2,597
colon cancer 9 | 1,478
ependymoma 9 | 4,679
lung carcinoma 9 | 2,843
spina bifida 9 | 1,074
ulcerative colitis 9 | 1,819
Dental fluorosis 8 | 20
Hypodontia 8 | 81
Intellectual disability 8 | 1,016
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
Dental Enamel Hypoplasia 7 | 43
Dentinogenesis imperfecta 7 | 25
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Seizures 7 | 596
Short stature 7 | 531
diabetes mellitus 7 | 1,728
gastric carcinoma 7 | 807
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Ameloblastoma 6 | 24
Anodontia 6 | 12
Breast Neoplasms 6 | 445
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Kidney cancer 6 | 2,613
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Oligodontia 6 | 24
Polydactyly 6 | 107
Poor school performance 6 | 645
Rickets 6 | 49
Root resorption 6 | 22
Small head 6 | 374
active ulcerative colitis 6 | 764
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
pediatric high grade glioma 6 | 1,064
Craniosynostosis 5 | 74
Decreased projection of midface 5 | 105
Decreased size of teeth 5 | 62
Decreased width of tooth 5 | 59
Epilepsy 5 | 792
Fuhrmann syndrome 5 | 7
Heart disease 5 | 306
Holoprosencephaly 5 | 56
Hydrocephalus 5 | 152
Hypohidrotic ectodermal dysplasia 5 | 15
Hypotrophic malar bone 5 | 129
Hypotrophic midface 5 | 105
Malar flattening 5 | 129
Microcephaly 5 | 166
Microdontia (disorder) 5 | 59
Microphthalmia 5 | 76
Midface retrusion 5 | 105
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
Small midface 5 | 105
Synostosis 5 | 15
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035

Tissue

Endocrine System 56 | 18,159
Digestive Tract 53 | 17,369
Female tissues 53 | 17,400
Blood and immune system 51 | 16,909
Male tissues 51 | 17,142
Liver and Pancreas 50 | 16,750
Skin and soft tissues 50 | 17,230
Respiratory system 48 | 16,393
Urinary Tract 48 | 16,678
Nervous System 47 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 11 | 4,145
Transcription Factor 9 | 1,400
GPCR 1 | 408
Kinase 1 | 634
Transporter 1 | 473

Jensen-TM Tissue

Incisor 58 | 58
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Kallikrein-4 KLK4 Tchem Enzyme -3.66176 4527.4 196
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194
Serine/threonine-protein kinase PLK2 PLK2 Tchem Kinase -2.45914 273.4 179
Protein sprouty homolog 1 SPRY1 Tbio Non-IDG -2.19105 141.2 190
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.47746 2989.0 646
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Osteocalcin BGLAP Tbio Non-IDG -3.92412 7636.8 691