Development Level

Tbio 666 | 10,625
Tchem 340 | 1,890
Tclin 127 | 602
Tdark 17 | 7,003

IMPC Term

preweaning lethality, complete... 35 | 633
preweaning lethality, incomple... 20 | 260
embryonic lethality prior to t... 16 | 187
decreased lean body mass 15 | 195
enlarged heart 15 | 111
abnormal behavior 14 | 226
decreased total body fat amoun... 13 | 186
decreased bone mineral content 12 | 157
decreased bone mineral density 12 | 126
increased circulating alkaline... 12 | 119
decreased body length 11 | 108
abnormal retina morphology 10 | 100
abnormal sleep behavior 10 | 63
decreased circulating insulin ... 10 | 75
abnormal embryo size 9 | 112
decreased circulating triglyce... 9 | 83
decreased grip strength 9 | 123
increased mean corpuscular hem... 9 | 93
abnormal bone structure 8 | 131
decreased circulating glucose ... 8 | 121
embryonic lethality prior to o... 8 | 148
increased mean corpuscular vol... 8 | 91
abnormal heart morphology 7 | 51
decreased body weight 7 | 174
increased circulating HDL chol... 7 | 63
increased grip strength 7 | 83
increased or absent threshold ... 7 | 128
short tibia 7 | 82
tremors 7 | 34
abnormal lens morphology 6 | 73
decreased circulating HDL chol... 6 | 77
decreased circulating choleste... 6 | 85
decreased heart weight 6 | 44
hypoactivity 6 | 89
increased circulating choleste... 6 | 53
increased circulating sodium l... 6 | 71
increased lean body mass 6 | 107
male infertility 6 | 62
thrombocytopenia 6 | 46
abnormal epididymis morphology 5 | 31
abnormal gait 5 | 51
abnormal retinal pigmentation 5 | 61
abnormal skin morphology 5 | 23
enlarged epididymis 5 | 27
improved glucose tolerance 5 | 56
increased body weight 5 | 42
increased circulating potassiu... 5 | 31
increased circulating triglyce... 5 | 24
cataract 4 | 26
decreased NK T cell number 4 | 28
decreased circulating alanine ... 4 | 53
decreased circulating alkaline... 4 | 41
decreased circulating free fat... 4 | 39
decreased erythrocyte cell num... 4 | 43
decreased leukocyte cell numbe... 4 | 54
decreased mean corpuscular vol... 4 | 50
decreased rib number 4 | 59
enlarged spleen 4 | 26
female infertility 4 | 34
increased circulating serum al... 4 | 25
increased erythrocyte cell num... 4 | 26
increased hematocrit 4 | 36
increased hemoglobin content 4 | 45
increased leukocyte cell numbe... 4 | 37
increased total body fat amoun... 4 | 57
limb grasping 4 | 35
small superior vagus ganglion 4 | 20
small testis 4 | 37
abnormal QRS complex 3 | 25
abnormal bone mineralization 3 | 55
abnormal coat/hair pigmentatio... 3 | 54
abnormal eye morphology 3 | 38
abnormal femur morphology 3 | 14
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
abnormal optic disc morphology 3 | 10
abnormal retinal blood vessel ... 3 | 18
abnormal retinal vasculature m... 3 | 15
abnormal snout morphology 3 | 18
abnormal testis morphology 3 | 30
abnormal tooth morphology 3 | 24
abnormal whole-body plethysmog... 3 | 4
cardiovascular system phenotyp... 3 | 35
decreased B cell number 3 | 30
decreased caudal vertebrae num... 3 | 49
decreased circulating calcium ... 3 | 33
decreased circulating serum al... 3 | 79
decreased eosinophil cell numb... 3 | 41
decreased fasted circulating g... 3 | 49
decreased hematocrit 3 | 25
decreased hemoglobin content 3 | 53
decreased mean corpuscular hem... 3 | 34
decreased mean corpuscular hem... 3 | 19
hydrops fetalis 3 | 22
increased blood urea nitrogen ... 3 | 44
increased circulating total pr... 3 | 20
increased respiratory quotient 3 | 12
increased vertical activity 3 | 18

Disease

Cancer 824 | 2,346
psoriasis 625 | 6,685
ovarian cancer 593 | 8,484
osteosarcoma 567 | 7,933
lung cancer 509 | 4,466
glioblastoma 496 | 5,572
medulloblastoma, large-cell 396 | 6,234
lung carcinoma 371 | 2,844
diabetes mellitus 348 | 1,663
ulcerative colitis 339 | 2,087
invasive ductal carcinoma 316 | 2,950
malignant mesothelioma 311 | 3,162
interstitial cystitis 307 | 2,299
non-small cell lung cancer 304 | 2,798
pilocytic astrocytoma 301 | 3,086
lung adenocarcinoma 295 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 293 | 3,289
pancreatic cancer 286 | 2,300
tuberculosis 277 | 1,557
intraductal papillary-mucinous adenoma (IPMA) 274 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 269 | 2,988
Breast cancer 260 | 3,094
Rheumatoid Arthritis 246 | 1,160
pediatric high grade glioma 243 | 2,712
atypical teratoid / rhabdoid tumor 240 | 4,369
subependymal giant cell astrocytoma 231 | 2,287
Arthritis 204 | 248
cutaneous lupus erythematosus 204 | 1,056
cystic fibrosis 204 | 1,665
Kidney disease 198 | 396
breast carcinoma 184 | 1,614
Hypersensitivity reaction type II disease 183 | 235
oligodendroglioma 180 | 2,849
astrocytoma 178 | 1,493
Multiple Sclerosis 174 | 498
posterior fossa group A ependymoma 173 | 1,511
Asthma 171 | 349
primitive neuroectodermal tumor 171 | 3,031
colon cancer 165 | 1,475
juvenile dermatomyositis 164 | 1,189
ductal carcinoma in situ 162 | 1,745
pituitary cancer 162 | 1,972
Carcinoma 161 | 2,147
primary pancreatic ductal adenocarcinoma 161 | 1,271
adrenocortical carcinoma 156 | 1,427
Vascular disease 155 | 281
pancreatic ductal adenocarcinoma liver metastasis 152 | 1,795
primary Sjogren syndrome 150 | 789
Atherosclerosis 148 | 275
group 4 medulloblastoma 148 | 1,875
ependymoma 146 | 2,514
adult high grade glioma 140 | 2,148
Multiple myeloma 139 | 1,327
group 3 medulloblastoma 134 | 2,254
Anemia 133 | 252
acute quadriplegic myopathy 131 | 1,157
Alzheimer's disease 129 | 644
Liver disease 129 | 219
dermatomyositis 129 | 933
Mammary Neoplasms 127 | 410
Obesity 126 | 616
Prostatic Neoplasms 126 | 471
Atopic dermatitis 125 | 944
Hypertension 119 | 287
gastric carcinoma 119 | 832
esophageal adenocarcinoma 115 | 737
astrocytic glioma 113 | 2,241
nasopharyngeal carcinoma 113 | 1,056
Acquired immunodeficiency syndrome 111 | 164
Heart disease 107 | 279
Duchenne muscular dystrophy 106 | 602
Cerebrovascular disease 105 | 231
Lung disease 104 | 132
mucosa-associated lymphoid tissue lymphoma 104 | 480
Pick disease 102 | 1,893
Inflammatory bowel disease 101 | 142
Coronary artery disease 100 | 240
active Crohn's disease 100 | 918
Ankylosing spondylitis 98 | 138
Down syndrome 95 | 548
Waldenstrons macroglobulinemia 95 | 765
IGA Glomerulonephritis 87 | 454
Uveitis 86 | 103
sonic hedgehog group medulloblastoma 86 | 1,482
Endometriosis 84 | 535
Lung Neoplasms 84 | 171
atypical teratoid/rhabdoid tumor 84 | 1,095
medulloblastoma 84 | 1,524
periodontitis 83 | 269
Juvenile rheumatoid arthritis 80 | 104
Stomach Neoplasms 79 | 282
acute myeloid leukemia 79 | 780
hepatocellular carcinoma 75 | 532
sarcoidosis 75 | 358
pancreatic carcinoma 74 | 567
Allergic hypersensitivity disease 73 | 123
Liver carcinoma 73 | 217
Peripheral Neuropathy 73 | 303
autosomal dominant Emery-Dreifuss muscular dystrophy 73 | 499
non-small cell lung carcinoma 72 | 413

Tissue

Female tissues 1,061 | 18,647
Nervous System 1,061 | 18,561
Digestive Tract 1,057 | 18,473
Endocrine System 1,057 | 18,512
Urinary Tract 1,057 | 18,444
Blood and immune system 1,056 | 17,995
Liver and Pancreas 1,053 | 18,136
Respiratory system 1,046 | 17,484
Male tissues 1,045 | 17,969
Cardiovascular System 1,041 | 17,958
Skin and soft tissues 1,038 | 18,115

Target Family

Non-IDG 686 | 11,971
Enzyme 217 | 4,146
Transcription Factor 85 | 1,400
Kinase 77 | 634
GPCR 38 | 406
Epigenetic 17 | 242
Transporter 11 | 473
Ion Channel 9 | 341
Nuclear Receptor 9 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Immune system 1,150 | 1,150
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303