Development Level

Tbio 761 | 11,651
Tchem 289 | 1,388
Tclin 138 | 612
Tdark 17 | 6,593

Collection

GPCR: IDG Consortium (Complete... 3 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 61 | 979
preweaning lethality, incomple... 35 | 499
enlarged heart 25 | 210
decreased vertical activity 24 | 208
embryonic lethality prior to t... 23 | 278
abnormal heart morphology 19 | 162
abnormal behavior 16 | 298
abnormal seminal vesicle morph... 15 | 114
abnormal embryo size 14 | 220
decreased total body fat amoun... 14 | 207
embryonic lethality prior to o... 14 | 239
decreased lymphocyte cell numb... 13 | 83
increased neutrophil cell numb... 13 | 46
decreased bone mineral content 12 | 151
increased total body fat amoun... 12 | 134
abnormal bone structure 11 | 187
decreased bone mineral density 11 | 126
decreased circulating insulin ... 11 | 76
decreased circulating triglyce... 11 | 79
increased circulating alkaline... 11 | 122
increased lean body mass 11 | 172
short tibia 11 | 97
abnormal retina morphology 10 | 71
abnormal sleep behavior 10 | 70
decreased mean corpuscular vol... 10 | 79
male infertility 10 | 123
cataract 9 | 92
decreased circulating glucose ... 9 | 126
decreased lean body mass 9 | 135
hypoactivity 9 | 132
increased mean corpuscular hem... 9 | 96
small superior vagus ganglion 9 | 74
abnormal lens morphology 8 | 81
decreased circulating choleste... 8 | 93
female infertility 8 | 60
improved glucose tolerance 8 | 79
increased circulating HDL chol... 8 | 80
increased mean corpuscular vol... 8 | 92
increased monocyte cell number 8 | 63
thrombocytopenia 8 | 56
abnormal gait 7 | 69
abnormal skin morphology 7 | 50
decreased body weight 7 | 161
decreased circulating HDL chol... 7 | 68
decreased heart weight 7 | 27
hyperactivity 7 | 148
impaired righting response 7 | 26
increased circulating choleste... 7 | 66
increased grip strength 7 | 41
decreased body length 6 | 101
edema 6 | 59
embryonic growth retardation 6 | 106
enlarged spleen 6 | 41
impaired glucose tolerance 6 | 75
increased bone mineral content 6 | 108
increased circulating sodium l... 6 | 71
increased erythrocyte cell num... 6 | 39
increased leukocyte cell numbe... 6 | 47
increased startle reflex 6 | 112
tremors 6 | 39
abnormal eye morphology 5 | 68
abnormal retinal blood vessel ... 5 | 26
abnormal retinal vasculature m... 5 | 27
abnormal spleen morphology 5 | 55
abnormal testis morphology 5 | 43
decreased blood urea nitrogen ... 5 | 51
decreased circulating amylase ... 5 | 28
decreased circulating serum al... 5 | 82
decreased erythrocyte cell num... 5 | 62
decreased grip strength 5 | 116
decreased hemoglobin content 5 | 68
decreased leukocyte cell numbe... 5 | 73
decreased startle reflex 5 | 75
hydrometra 5 | 53
increased circulating potassiu... 5 | 29
increased circulating triglyce... 5 | 42
increased hemoglobin content 5 | 45
increased or absent threshold ... 5 | 101
increased spleen weight 5 | 10
limb grasping 5 | 41
prolonged QT interval 5 | 38
abnormal epididymis morphology 4 | 42
abnormal lung morphology 4 | 26
cardiovascular system phenotyp... 4 | 36
decreased circulating alkaline... 4 | 46
decreased hematocrit 4 | 46
decreased mean corpuscular hem... 4 | 50
decreased mean corpuscular hem... 4 | 31
decreased neutrophil cell numb... 4 | 42
decreased red blood cell distr... 4 | 41
enlarged lymph nodes 4 | 37
increased blood urea nitrogen ... 4 | 48
increased bone mineral density 4 | 72
increased circulating iron lev... 4 | 30
increased circulating serum al... 4 | 22
increased fasted circulating g... 4 | 76
microphthalmia 4 | 26
prenatal lethality prior to he... 4 | 87
small testis 4 | 58
thin ventricular wall 4 | 24

Disease

Cancer 879 | 2,499
Carcinoma 743 | 11,493
psoriasis 661 | 6,694
ovarian cancer 637 | 8,520
osteosarcoma 595 | 7,950
lung cancer 560 | 4,740
glioblastoma 549 | 5,792
medulloblastoma, large-cell 418 | 6,241
lung carcinoma 391 | 2,843
diabetes mellitus 375 | 1,728
malignant mesothelioma 356 | 3,232
tuberculosis 345 | 2,010
invasive ductal carcinoma 339 | 2,951
Breast cancer 338 | 3,578
non-small cell lung cancer 335 | 2,890
interstitial cystitis 325 | 2,312
ependymoma 324 | 4,679
pancreatic cancer 317 | 2,398
Astrocytoma, Pilocytic 313 | 3,081
atypical teratoid / rhabdoid tumor 313 | 5,112
lung adenocarcinoma 313 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 312 | 3,291
ulcerative colitis 312 | 1,819
adult high grade glioma 299 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 290 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 287 | 2,989
group 3 medulloblastoma 265 | 4,104
Rheumatoid arthritis 255 | 1,191
subependymal giant cell astrocytoma 240 | 2,287
Schizophrenia 222 | 1,160
cystic fibrosis 222 | 1,696
Arthritis 221 | 290
cutaneous lupus erythematosus 214 | 1,057
Kidney disease 205 | 430
breast carcinoma 204 | 1,638
Hypersensitivity reaction type II disease 192 | 253
oligodendroglioma 192 | 2,850
Liver Cirrhosis, Experimental 188 | 769
primitive neuroectodermal tumor 186 | 3,035
Multiple Sclerosis 185 | 540
pancreatic ductal adenocarcinoma liver metastasis 184 | 1,962
Asthma 180 | 385
colon cancer 177 | 1,478
ductal carcinoma in situ 177 | 1,745
pituitary cancer 175 | 1,972
Kidney cancer 174 | 2,613
juvenile dermatomyositis 172 | 1,187
Autosomal recessive predisposition 170 | 1,442
adrenocortical carcinoma 169 | 1,428
dermatomyositis 169 | 966
Vascular disease 168 | 319
astrocytic glioma 161 | 2,597
Anemia 160 | 365
Hypertension 157 | 396
Atherosclerosis 156 | 291
astrocytoma 147 | 1,146
primary Sjogren syndrome 147 | 735
Multiple myeloma 145 | 1,332
Obesity 143 | 678
primary pancreatic ductal adenocarcinoma 143 | 1,109
Alzheimer's disease 140 | 658
Liver disease 139 | 237
group 4 medulloblastoma 139 | 1,855
Atopic dermatitis 136 | 952
Breast Neoplasms 135 | 445
Mammary Neoplasms 134 | 425
acute quadriplegic myopathy 134 | 1,158
Prostatic Neoplasms 131 | 495
Bipolar Disorder 125 | 666
nasopharyngeal carcinoma 123 | 1,058
esophageal adenocarcinoma 122 | 737
Coronary artery disease 116 | 268
Cerebrovascular disease 113 | 238
Acquired immunodeficiency syndrome 112 | 197
Heart disease 112 | 306
Duchenne muscular dystrophy 111 | 601
gastric carcinoma 111 | 807
Dermatitis 109 | 157
Pick disease 109 | 1,894
Inflammatory bowel disease 108 | 151
Lung disease 108 | 142
active Crohn's disease 108 | 922
mucosa-associated lymphoid tissue lymphoma 108 | 484
Human immunodeficiency virus infectious disease 107 | 138
pediatric high grade glioma 103 | 1,064
Waldenstrons macroglobulinemia 101 | 765
Melanoma 100 | 711
Ankylosing spondylitis 99 | 140
Depressive disorder 99 | 409
Lung Neoplasms 99 | 232
active ulcerative colitis 97 | 764
Down syndrome 95 | 499
Hypertensive disease 93 | 292
periodontitis 92 | 293
Pneumonia 90 | 174
acute myeloid leukemia 89 | 783
Intellectual disability 88 | 1,016
Stomach Neoplasms 88 | 300
Endometriosis 87 | 540
hepatocellular carcinoma 87 | 547

Tissue

Digestive Tract 1,092 | 17,369
Endocrine System 1,092 | 18,159
Skin and soft tissues 1,089 | 17,230
Blood and immune system 1,088 | 16,909
Female tissues 1,087 | 17,400
Urinary Tract 1,082 | 16,678
Liver and Pancreas 1,081 | 16,750
Male tissues 1,075 | 17,142
Respiratory system 1,068 | 16,393
Nervous System 1,051 | 16,725
Cardiovascular System 996 | 15,192

Target Family

Non-IDG 718 | 12,091
Enzyme 227 | 4,145
Transcription Factor 88 | 1,400
Kinase 82 | 634
GPCR 40 | 408
Epigenetic 17 | 242
Transporter 12 | 473
Ion Channel 11 | 344
Nuclear Receptor 9 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Immune system 1,205 | 1,205
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275