Development Level

Tbio 41 | 11,445
Tclin 11 | 613
Tchem 7 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 3 | 126

IMPC Phenotype

abnormal bone structure 7 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
preweaning lethality, incomple... 3 | 499
decreased bone mineral content 2 | 151
decreased hemoglobin content 2 | 68
small spleen 2 | 19
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal male genitalia morpho... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
absent startle reflex 1 | 24
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
polysyndactyly 1 | 2
preweaning lethality, complete... 1 | 979
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
thrombocytopenia 1 | 56
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 41 | 11,493
psoriasis 25 | 6,694
Autosomal recessive predisposition 23 | 1,442
ovarian cancer 23 | 8,520
Adenoma 19 | 167
Hypothyroidism 19 | 122
pituitary cancer 19 | 1,972
Cancer 18 | 2,499
Pituitary adenoma 17 | 38
lung cancer 17 | 4,740
Hypopituitarism 15 | 40
Infertility 14 | 188
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
Breast cancer 13 | 3,578
Cushing's syndrome 13 | 48
Hypogonadotropic hypogonadism 13 | 89
Polycystic ovary syndrome 13 | 360
Acromegaly 12 | 51
Amenorrhea 12 | 58
Fatigue 12 | 182
Hypogonadism 12 | 173
Hyperthyroidism 11 | 53
Kidney cancer 11 | 2,613
Osteoporosis 11 | 363
Short stature 11 | 531
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
Coarse facial features 10 | 108
Intellectual disability 10 | 1,016
McCune Albright syndrome 10 | 19
Obesity 10 | 678
Thickened facial skin with coarse facial features 10 | 108
diabetes mellitus 10 | 1,728
ductal carcinoma in situ 10 | 1,745
Constipation 9 | 181
Generalized osteopenia 9 | 99
Hypoglycemia 9 | 152
Hypogonadism, Isolated Hypogonadotropic 9 | 71
Osteopenia 9 | 99
Septooptic dysplasia 9 | 19
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
Abdomen distended 8 | 43
Carney complex 8 | 25
Cognitive delay 8 | 608
Congenital adrenal hyperplasia 8 | 73
Delayed Puberty 8 | 97
Dull intelligence 8 | 645
Dyschezia 8 | 135
Feeding difficulties 8 | 127
Global developmental delay 8 | 608
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Multiple Endocrine Neoplasia Type 1 8 | 29
Muscle hypotonia 8 | 571
Pituitary hypoplasia 8 | 23
Poor school performance 8 | 645
Sleep disturbances 8 | 37
Umbilical hernia 8 | 93
ependymoma 8 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primitive neuroectodermal tumor 8 | 3,035
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Brachydactyly 7 | 156
Decreased circulating ACTH level 7 | 12
Delayed bone age 7 | 136
Depressive disorder 7 | 409
Endometriosis 7 | 540
Holoprosencephaly 7 | 56
Hypertensive disease 7 | 292
Hypotension 7 | 82
Icterus 7 | 82
Isolated somatotropin deficiency 7 | 30
Large bregma sutures 7 | 46
Large fontanelle 7 | 46
Large, late-closing fontanelle 7 | 46
Secondary hypothyroidism 7 | 15
Small testicle 7 | 75
Wide bregma sutures 7 | 46
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
oligodendroglioma 7 | 2,850
Atopic dermatitis 6 | 952
Epilepsy 6 | 792
Increase in blood pressure 6 | 119
Liver Cirrhosis, Experimental 6 | 769
Liver cancer 6 | 604
Male infertility 6 | 206
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
subependymal giant cell astrocytoma 6 | 2,287

Tissue

Endocrine System 52 | 18,159
Digestive Tract 45 | 17,369
Liver and Pancreas 44 | 16,750
Female tissues 43 | 17,400
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Nervous System 42 | 16,725
Male tissues 37 | 17,142
Respiratory system 36 | 16,393
Urinary Tract 36 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 28 | 12,091
GPCR 12 | 408
Enzyme 9 | 4,145
Transcription Factor 8 | 1,400
Nuclear Receptor 2 | 48
Kinase 1 | 634

Jensen-TM Tissue

Hypophysis 60 | 60
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Pro-FMRFamide-related neuropeptide VF NPVF Tdark Non-IDG -1.78438 62.6 22
Chorionic somatomammotropin hormone 2 CSH2 Tbio Non-IDG -2.95755 830.6 89
Putative gonadotropin-releasing hormone II receptor GNRHR2 Tbio GPCR -1.36285 20.4 0
Probable G-protein coupled receptor 101 GPR101 Tbio GPCR -1.13310 16.7 157
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tbio Nuclear Receptor -2.73235 544.8 477
Glycogen phosphorylase, muscle form PYGM Tchem Enzyme -2.24324 158.2 208
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.43406 2729.3 264