Development Level

Tbio 69 | 11,651
Tchem 23 | 1,388
Tclin 13 | 612
Tdark 3 | 6,593

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
abnormal skin morphology 3 | 50
decreased circulating creatini... 3 | 39
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
short tibia 3 | 97
abnormal embryo size 2 | 220
abnormal snout morphology 2 | 23
decreased bone mineral content 2 | 151
decreased circulating aspartat... 2 | 34
decreased lactate dehydrogenas... 2 | 16
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
hydrometra 2 | 53
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
prolonged PR interval 2 | 15
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lip morphology 1 | 2
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
corneal opacity 1 | 32
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
hydroencephaly 1 | 14
hyperactivity 1 | 148
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
prolonged PQ interval 1 | 5
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 73 | 11,493
Cancer 62 | 2,499
ovarian cancer 52 | 8,520
diabetes mellitus 51 | 1,728
psoriasis 47 | 6,694
Osteoporosis 41 | 363
Obesity 40 | 678
Hypertension 39 | 396
Coronary artery disease 36 | 268
Kidney disease 36 | 430
lung cancer 36 | 4,740
osteosarcoma 36 | 7,950
Autosomal recessive predisposition 35 | 1,442
interstitial cystitis 34 | 2,312
Arthritis 33 | 290
Atherosclerosis 33 | 291
Cerebrovascular disease 33 | 238
glioblastoma 29 | 5,792
Heart disease 28 | 306
Liver disease 28 | 237
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
non-small cell lung cancer 27 | 2,890
invasive ductal carcinoma 26 | 2,951
pancreatic cancer 26 | 2,398
Osteoarthritis 25 | 184
lung carcinoma 25 | 2,843
Astrocytoma, Pilocytic 24 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
tuberculosis 24 | 2,010
ulcerative colitis 24 | 1,819
Anemia 23 | 365
Breast cancer 23 | 3,578
medulloblastoma, large-cell 23 | 6,241
Hypertensive disease 21 | 292
Polycystic ovary syndrome 21 | 360
Lipid metabolism disorder 20 | 114
Rheumatoid arthritis 20 | 1,191
ductal carcinoma in situ 20 | 1,745
Hypersensitivity reaction type II disease 19 | 253
Liver Cirrhosis, Experimental 19 | 769
Schizophrenia 19 | 1,160
cystic fibrosis 19 | 1,696
ependymoma 19 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung adenocarcinoma 19 | 2,716
pituitary cancer 19 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Hyperglycemia 17 | 137
Kidney cancer 17 | 2,613
Prostatic Neoplasms 17 | 495
Pulmonary embolism 17 | 55
adult high grade glioma 17 | 3,801
breast carcinoma 17 | 1,638
malignant mesothelioma 17 | 3,232
Heart failure 16 | 162
Hyperinsulinism 16 | 133
Hyperparathyroidism 16 | 48
Short stature 16 | 531
Thrombocytopenia 16 | 197
Breast Neoplasms 15 | 445
Fatty liver disease 15 | 103
Hypothyroidism 15 | 122
Mammary Neoplasms 15 | 425
atypical teratoid / rhabdoid tumor 15 | 5,112
Arthropathy 14 | 43
Alzheimer's disease 13 | 658
Asthma 13 | 385
Brain disease 13 | 96
Degenerative disc disease 13 | 35
Degenerative polyarthritis 13 | 115
Dementia 13 | 175
Diarrhea 13 | 253
Lung disease 13 | 142
Osteonecrosis 13 | 27
adrenocortical carcinoma 13 | 1,428
gastric carcinoma 13 | 807
primary pancreatic ductal adenocarcinoma 13 | 1,109
Ankylosing spondylitis 12 | 140
Arthritis, Rheumatoid 12 | 174
Atopic dermatitis 12 | 952
Cholestasis 12 | 155
Depressive disorder 12 | 409
Hypercalcemia 12 | 59
Pancreatitis 12 | 123
Peripheral vascular disease 12 | 87
Pneumonia 12 | 174
Synovitis 12 | 78
Vasculitis 12 | 80
group 3 medulloblastoma 12 | 4,104
oligodendroglioma 12 | 2,850
Infertility 11 | 188
Inflammation 11 | 120
Inflammatory bowel disease 11 | 151
Osteomyelitis 11 | 42
astrocytic glioma 11 | 2,597
cutaneous lupus erythematosus 11 | 1,057
periodontitis 11 | 293
Bipolar Disorder 10 | 666
Endometriosis 10 | 540
Epilepsy 10 | 792

Tissue

Digestive Tract 105 | 17,369
Endocrine System 105 | 18,159
Liver and Pancreas 104 | 16,750
Skin and soft tissues 104 | 17,230
Female tissues 101 | 17,400
Urinary Tract 101 | 16,678
Male tissues 99 | 17,142
Blood and immune system 97 | 16,909
Respiratory system 96 | 16,393
Nervous System 93 | 16,725
Cardiovascular System 86 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 25 | 4,145
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
GPCR 1 | 408

Jensen-TM Tissue

Hip 108 | 108
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667