Development Level

Tbio 257 | 10,625
Tchem 68 | 1,890
Tclin 44 | 602
Tdark 1 | 7,003

IMPC Phenotype

preweaning lethality, complete... 13 | 633
preweaning lethality, incomple... 7 | 260
decreased lean body mass 6 | 195
limb grasping 6 | 35
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
decreased erythrocyte cell num... 4 | 43
decreased hemoglobin content 4 | 53
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
increased blood urea nitrogen ... 4 | 44
increased circulating HDL chol... 4 | 63
increased grip strength 4 | 83
increased total body fat amoun... 4 | 57
abnormal bone mineralization 3 | 55
abnormal lens morphology 3 | 73
abnormal startle reflex 3 | 14
cataract 3 | 26
decreased circulating free fat... 3 | 39
decreased grip strength 3 | 123
decreased hematocrit 3 | 25
impaired pupillary reflex 3 | 14
increased monocyte cell number 3 | 27
abnormal bone structure 2 | 131
abnormal cornea morphology 2 | 24
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal locomotor activation 2 | 26
abnormal sleep behavior 2 | 63
corneal opacity 2 | 25
decreased circulating alkaline... 2 | 41
decreased circulating insulin ... 2 | 75
decreased circulating iron lev... 2 | 25
decreased circulating triglyce... 2 | 83
decreased effector memory CD8-... 2 | 24
decreased kidney weight 2 | 7
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
increased circulating alkaline... 2 | 119
increased circulating amylase ... 2 | 13
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
increased exploration in new e... 2 | 56
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
increased respiratory quotient 2 | 12
increased sacral vertebrae num... 2 | 62
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal whole-body plethysmog... 1 | 4
decreased CD4-positive, CD25-p... 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased monocyte cell number 1 | 28
decreased spleen weight 1 | 13
enlarged spleen 1 | 26
female infertility 1 | 34
hydrometra 1 | 13
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased Ly6C high monocyte n... 1 | 12
increased NK cell number 1 | 19
increased blood uric acid leve... 1 | 5
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased lean body mass 1 | 107
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 25
increased prepulse inhibition 1 | 21
increased vertical activity 1 | 18
mydriasis 1 | 9
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small superior vagus ganglion 1 | 20
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

Cancer 323 | 2,346
psoriasis 197 | 6,685
osteosarcoma 157 | 7,933
diabetes mellitus 140 | 1,663
ovarian cancer 138 | 8,491
glioblastoma 136 | 5,572
lung cancer 136 | 4,473
Hypersensitivity reaction type II disease 112 | 235
medulloblastoma, large-cell 111 | 6,234
Arthritis 102 | 248
Rheumatoid Arthritis 98 | 1,170
malignant mesothelioma 98 | 3,163
invasive ductal carcinoma 92 | 2,950
interstitial cystitis 90 | 2,299
Breast cancer 88 | 3,098
Anemia 87 | 252
lung carcinoma 87 | 2,844
Kidney disease 85 | 397
Multiple Sclerosis 83 | 498
pilocytic astrocytoma 83 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 82 | 3,289
tuberculosis 82 | 1,563
Acquired immunodeficiency syndrome 79 | 164
non-small cell lung cancer 79 | 2,798
Ankylosing spondylitis 78 | 138
intraductal papillary-mucinous carcinoma (IPMC) 78 | 2,988
lung adenocarcinoma 78 | 2,714
ulcerative colitis 77 | 2,087
Human immunodeficiency virus infectious disease 70 | 129
Liver disease 70 | 219
pancreatic cancer 70 | 2,300
Uveitis 68 | 103
dermatomyositis 68 | 966
atypical teratoid / rhabdoid tumor 66 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,956
pediatric high grade glioma 65 | 2,712
Juvenile rheumatoid arthritis 63 | 105
Dermatitis 62 | 141
ductal carcinoma in situ 62 | 1,745
oligodendroglioma 61 | 2,849
Carcinoma 60 | 2,147
subependymal giant cell astrocytoma 58 | 2,287
Mammary Neoplasms 57 | 410
cutaneous lupus erythematosus 57 | 1,056
Behcet's disease 56 | 74
Psoriatic arthritis 56 | 85
cystic fibrosis 56 | 1,670
Stevens-Johnson syndrome 55 | 91
pituitary cancer 54 | 1,972
primitive neuroectodermal tumor 53 | 3,031
breast carcinoma 52 | 1,614
group 4 medulloblastoma 49 | 1,875
Asthma 45 | 349
adult high grade glioma 45 | 2,148
Synovitis 44 | 72
Prostatic Neoplasms 43 | 471
posterior fossa group A ependymoma 41 | 1,511
Heart disease 40 | 279
astrocytoma 40 | 1,493
Hepatitis B 39 | 103
colon cancer 39 | 1,475
Lung disease 38 | 136
Nephritis 38 | 63
nasopharyngeal carcinoma 38 | 1,056
primary pancreatic ductal adenocarcinoma 38 | 1,271
Behcet's syndrome 37 | 50
Inflammatory bowel disease 37 | 142
Takayasu's arteritis 37 | 54
Vascular disease 37 | 281
Cerebrovascular disease 36 | 231
Congenital adrenal hyperplasia 36 | 74
astrocytic glioma 36 | 2,241
ependymoma 36 | 2,514
group 3 medulloblastoma 36 | 2,254
Alzheimer's disease 35 | 644
Atherosclerosis 35 | 275
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Thrombocytopenia 35 | 105
drug-induced hepatitis 35 | 44
primary Sjogren syndrome 35 | 788
Primary immunodeficiency disease 34 | 52
adrenocortical carcinoma 34 | 1,427
Coronary artery disease 33 | 240
Lung Neoplasms 33 | 171
Stomach Neoplasms 33 | 282
Down syndrome 32 | 548
Leprosy 32 | 77
Osteoporosis 32 | 259
esophageal adenocarcinoma 32 | 737
Adenoma 31 | 165
Obesity 31 | 616
Skin disease 31 | 65
juvenile dermatomyositis 31 | 1,189
Hypertension 30 | 293
acute quadriplegic myopathy 30 | 1,157
Endometriosis 29 | 535
Multiple myeloma 29 | 1,327
gastric carcinoma 29 | 832
sarcoidosis 29 | 368

Tissue

Endocrine System 304 | 18,511
Female tissues 303 | 18,646
Nervous System 303 | 18,560
Digestive Tract 301 | 18,472
Urinary Tract 301 | 18,443
Liver and Pancreas 299 | 18,135
Blood and immune system 298 | 17,994
Male tissues 297 | 17,968
Cardiovascular System 295 | 17,957
Skin and soft tissues 292 | 18,114
Respiratory system 290 | 17,483

Target Family

Non-IDG 232 | 11,969
Transcription Factor 73 | 1,400
Enzyme 34 | 4,146
Kinase 17 | 634
Epigenetic 5 | 242
GPCR 3 | 408
Nuclear Receptor 3 | 48
Ion Channel 1 | 341
TF/Epigenetic 1 | 38
Transporter 1 | 473

Jensen-TM Tissue

Hematopoietic stem cell 370 | 370
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.03044 1092.0 356
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.66256 471.8 306
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.70375 8561.3 896
Prominin-1 PROM1 Tbio Non-IDG -3.27144 1922.5 226
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539