Development Level

Tbio 460 | 10,625
Tchem 274 | 1,890
Tclin 137 | 602
Tdark 10 | 7,003

IMPC Term

preweaning lethality, complete... 46 | 633
embryonic lethality prior to t... 18 | 187
abnormal behavior 16 | 226
decreased body weight 14 | 174
decreased lean body mass 14 | 195
decreased bone mineral content 13 | 157
preweaning lethality, incomple... 13 | 260
abnormal embryo size 12 | 112
decreased bone mineral density 11 | 126
decreased total body fat amoun... 11 | 186
embryonic lethality prior to o... 11 | 148
abnormal retina morphology 10 | 100
enlarged heart 10 | 111
increased total body fat amoun... 10 | 57
abnormal gait 8 | 51
decreased body length 8 | 108
decreased circulating alanine ... 8 | 53
decreased circulating insulin ... 8 | 75
increased circulating choleste... 8 | 53
decreased circulating HDL chol... 7 | 77
increased circulating HDL chol... 7 | 63
increased circulating alkaline... 7 | 119
abnormal lens morphology 6 | 73
abnormal neural tube closure 6 | 37
decreased circulating triglyce... 6 | 83
decreased fasted circulating g... 6 | 49
increased grip strength 6 | 83
increased lean body mass 6 | 107
increased mean corpuscular vol... 6 | 91
thrombocytopenia 6 | 46
abnormal epididymis morphology 5 | 31
abnormal forebrain development 5 | 18
abnormal heart morphology 5 | 51
abnormal hindbrain development 5 | 24
abnormal midbrain development 5 | 22
abnormal sleep behavior 5 | 63
cataract 5 | 26
decreased blood urea nitrogen ... 5 | 31
decreased circulating LDL chol... 5 | 37
decreased circulating alkaline... 5 | 41
decreased circulating amylase ... 5 | 24
decreased circulating calcium ... 5 | 33
decreased circulating choleste... 5 | 85
decreased circulating glucose ... 5 | 121
decreased eosinophil cell numb... 5 | 41
decreased grip strength 5 | 123
hyperactivity 5 | 108
hypoactivity 5 | 89
increased bone mineral content 5 | 92
increased circulating calcium ... 5 | 32
increased circulating phosphat... 5 | 24
increased or absent threshold ... 5 | 128
abnormal behavioral response t... 4 | 52
abnormal bone mineralization 4 | 55
abnormal bone structure 4 | 131
abnormal retinal pigmentation 4 | 61
abnormal tooth morphology 4 | 24
cardiovascular system phenotyp... 4 | 35
decreased circulating creatini... 4 | 31
decreased erythrocyte cell num... 4 | 43
decreased heart weight 4 | 44
decreased lumbar vertebrae num... 4 | 62
decreased mean corpuscular vol... 4 | 50
decreased startle reflex 4 | 48
enlarged epididymis 4 | 27
impaired glucose tolerance 4 | 52
improved glucose tolerance 4 | 56
increased blood urea nitrogen ... 4 | 44
increased bone mineral density 4 | 52
increased circulating total pr... 4 | 20
increased circulating triglyce... 4 | 24
increased heart weight 4 | 37
increased hemoglobin content 4 | 45
increased mean corpuscular hem... 4 | 93
limb grasping 4 | 35
small testis 4 | 37
tremors 4 | 34
abnormal femur morphology 3 | 14
abnormal lung morphology 3 | 15
abnormal snout morphology 3 | 18
abnormal testis morphology 3 | 30
decreased circulating aspartat... 3 | 27
decreased circulating chloride... 3 | 32
decreased circulating glycerol... 3 | 19
decreased circulating serum al... 3 | 79
decreased circulating total pr... 3 | 41
decreased hematocrit 3 | 25
decreased prepulse inhibition 3 | 52
enlarged lymph nodes 3 | 27
hydrops fetalis 3 | 22
impaired righting response 3 | 19
increased body weight 3 | 42
increased circulating potassiu... 3 | 31
increased circulating serum al... 3 | 25
increased fasted circulating g... 3 | 68
increased hematocrit 3 | 36
increased sacral vertebrae num... 3 | 62
increased vertical activity 3 | 18
persistence of hyaloid vascula... 3 | 22
short tibia 3 | 82

Disease

Cancer 527 | 2,346
ovarian cancer 482 | 8,484
psoriasis 450 | 6,685
osteosarcoma 389 | 7,933
lung cancer 379 | 4,466
glioblastoma 375 | 5,572
medulloblastoma, large-cell 328 | 6,234
diabetes mellitus 289 | 1,663
invasive ductal carcinoma 273 | 2,950
malignant mesothelioma 267 | 3,162
lung carcinoma 265 | 2,844
atypical teratoid / rhabdoid tumor 260 | 4,369
lung adenocarcinoma 260 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 246 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 244 | 3,289
non-small cell lung cancer 240 | 2,798
pilocytic astrocytoma 232 | 3,086
pancreatic cancer 231 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 230 | 2,988
ulcerative colitis 225 | 2,087
Breast cancer 222 | 3,094
Heart disease 204 | 279
Hypertension 204 | 287
Kidney disease 202 | 396
interstitial cystitis 201 | 2,299
cystic fibrosis 193 | 1,665
pediatric high grade glioma 190 | 2,712
Vascular disease 177 | 281
primitive neuroectodermal tumor 176 | 3,031
tuberculosis 176 | 1,557
oligodendroglioma 171 | 2,849
ductal carcinoma in situ 169 | 1,745
Atherosclerosis 167 | 275
Carcinoma 162 | 2,147
breast carcinoma 160 | 1,614
pituitary cancer 158 | 1,972
subependymal giant cell astrocytoma 157 | 2,287
Coronary artery disease 151 | 240
Obesity 151 | 616
Cerebrovascular disease 150 | 231
colon cancer 148 | 1,475
ependymoma 146 | 2,514
Rheumatoid Arthritis 138 | 1,160
adrenocortical carcinoma 132 | 1,427
posterior fossa group A ependymoma 130 | 1,511
astrocytoma 128 | 1,493
primary pancreatic ductal adenocarcinoma 127 | 1,271
Arthritis 124 | 248
adult high grade glioma 124 | 2,148
group 4 medulloblastoma 124 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 123 | 1,795
Alzheimer's disease 116 | 644
Asthma 116 | 349
acute quadriplegic myopathy 112 | 1,157
cutaneous lupus erythematosus 111 | 1,056
Mammary Neoplasms 110 | 410
gastric carcinoma 110 | 832
astrocytic glioma 105 | 2,241
juvenile dermatomyositis 104 | 1,189
group 3 medulloblastoma 100 | 2,254
Hypertensive disease 97 | 193
medulloblastoma 97 | 1,524
Prostatic Neoplasms 96 | 471
Multiple Sclerosis 95 | 498
Pick disease 95 | 1,893
Lung disease 94 | 132
Atopic dermatitis 89 | 944
Liver disease 89 | 219
Multiple myeloma 89 | 1,327
dermatomyositis 89 | 933
nasopharyngeal carcinoma 84 | 1,056
Hypersensitivity reaction type II disease 83 | 235
Anemia 82 | 252
Myocardial Infarction 78 | 126
Duchenne muscular dystrophy 77 | 602
Inflammatory bowel disease 77 | 142
esophageal adenocarcinoma 76 | 737
sonic hedgehog group medulloblastoma 75 | 1,482
Endometriosis 73 | 535
Stomach Neoplasms 71 | 282
Neoplasm Metastasis 70 | 138
atypical teratoid/rhabdoid tumor 70 | 1,095
fibroadenoma 70 | 557
Hyperglycemia 69 | 120
Schizophrenia 69 | 501
Down syndrome 68 | 548
Metabolic syndrome X 68 | 155
mucosa-associated lymphoid tissue lymphoma 68 | 480
Neurodegenerative disease 66 | 383
active Crohn's disease 66 | 918
Inflammation 64 | 109
Lung Neoplasms 64 | 171
non-small cell lung carcinoma 64 | 413
Heart failure 63 | 80
Liver carcinoma 63 | 217
Osteoporosis 63 | 257
Myocardial Ischemia 60 | 169
spina bifida 60 | 1,064
Reperfusion Injury 59 | 84
Waldenstrons macroglobulinemia 59 | 765

Tissue

Nervous System 863 | 18,561
Endocrine System 862 | 18,512
Female tissues 862 | 18,647
Digestive Tract 861 | 18,473
Urinary Tract 860 | 18,444
Skin and soft tissues 858 | 18,115
Liver and Pancreas 856 | 18,136
Blood and immune system 854 | 17,995
Cardiovascular System 854 | 17,958
Male tissues 852 | 17,969
Respiratory system 850 | 17,484

Target Family

Non-IDG 429 | 11,971
Enzyme 193 | 4,146
Kinase 69 | 634
Transcription Factor 68 | 1,400
Ion Channel 42 | 341
GPCR 39 | 406
Transporter 22 | 473
Epigenetic 12 | 242
Nuclear Receptor 6 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Heart 881 | 881
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160