Development Level

Tbio 517 | 11,445
Tchem 248 | 1,598
Tclin 141 | 613
Tdark 8 | 6,588

IMPC Phenotype

preweaning lethality, complete... 64 | 979
preweaning lethality, incomple... 30 | 499
embryonic lethality prior to t... 28 | 278
decreased vertical activity 21 | 208
enlarged heart 19 | 210
abnormal behavior 18 | 298
embryonic lethality prior to o... 18 | 239
abnormal embryo size 16 | 220
increased total body fat amoun... 15 | 134
decreased total body fat amoun... 14 | 207
abnormal heart morphology 13 | 162
decreased body weight 12 | 161
embryonic growth retardation 11 | 106
abnormal seminal vesicle morph... 10 | 114
decreased lean body mass 10 | 135
hypoactivity 10 | 132
increased circulating HDL chol... 10 | 80
increased startle reflex 10 | 112
abnormal gait 9 | 69
decreased bone mineral content 9 | 151
increased bone mineral content 9 | 108
increased circulating choleste... 9 | 66
increased lean body mass 9 | 172
abnormal bone structure 8 | 187
abnormal retina morphology 8 | 71
decreased lymphocyte cell numb... 8 | 83
abnormal lens morphology 7 | 81
decreased bone mineral density 7 | 126
decreased circulating HDL chol... 7 | 68
decreased circulating triglyce... 7 | 79
hyperactivity 7 | 148
increased circulating alkaline... 7 | 122
increased mean corpuscular vol... 7 | 92
increased neutrophil cell numb... 7 | 46
abnormal testis morphology 6 | 43
cataract 6 | 92
decreased body length 6 | 101
decreased circulating amylase ... 6 | 28
decreased circulating calcium ... 6 | 36
decreased circulating choleste... 6 | 93
decreased circulating creatini... 6 | 39
decreased circulating insulin ... 6 | 76
decreased erythrocyte cell num... 6 | 62
decreased fasted circulating g... 6 | 65
decreased grip strength 6 | 116
decreased mean corpuscular vol... 6 | 79
impaired glucose tolerance 6 | 75
increased circulating calcium ... 6 | 34
increased heart weight 6 | 62
increased monocyte cell number 6 | 63
male infertility 6 | 123
small superior vagus ganglion 6 | 74
small testis 6 | 58
abnormal behavioral response t... 5 | 66
abnormal epididymis morphology 5 | 42
abnormal lung morphology 5 | 26
decreased circulating LDL chol... 5 | 38
decreased circulating alanine ... 5 | 47
decreased neutrophil cell numb... 5 | 42
decreased prepulse inhibition 5 | 82
edema 5 | 59
impaired righting response 5 | 26
improved glucose tolerance 5 | 79
increased circulating total pr... 5 | 28
increased lymphocyte cell numb... 5 | 32
limb grasping 5 | 41
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
short tibia 5 | 97
thrombocytopenia 5 | 56
abnormal sleep behavior 4 | 70
decreased blood urea nitrogen ... 4 | 51
decreased circulating alkaline... 4 | 46
decreased circulating aspartat... 4 | 34
decreased circulating bilirubi... 4 | 19
decreased circulating glucose ... 4 | 126
decreased circulating serum al... 4 | 82
decreased hematocrit 4 | 46
enlarged epididymis 4 | 31
enlarged lymph nodes 4 | 37
increased bone mineral density 4 | 72
increased circulating iron lev... 4 | 30
increased circulating phosphat... 4 | 26
increased hemoglobin content 4 | 45
increased spleen weight 4 | 10
abnormal kidney morphology 3 | 65
abnormal skin morphology 3 | 50
abnormal vertebrae morphology 3 | 18
decreased T cell number 3 | 15
decreased circulating total pr... 3 | 49
decreased hemoglobin content 3 | 68
decreased startle reflex 3 | 75
enlarged spleen 3 | 41
increased circulating chloride... 3 | 41
increased circulating serum al... 3 | 22
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
tremors 3 | 39

Disease

Carcinoma 603 | 11,493
Cancer 562 | 2,499
ovarian cancer 503 | 8,520
psoriasis 465 | 6,694
osteosarcoma 406 | 7,950
lung cancer 405 | 4,740
glioblastoma 399 | 5,792
medulloblastoma, large-cell 345 | 6,241
diabetes mellitus 314 | 1,728
atypical teratoid / rhabdoid tumor 313 | 5,112
malignant mesothelioma 300 | 3,232
ependymoma 289 | 4,679
Breast cancer 286 | 3,578
invasive ductal carcinoma 283 | 2,951
lung adenocarcinoma 271 | 2,716
lung carcinoma 269 | 2,843
non-small cell lung cancer 264 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 255 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 251 | 2,955
Hypertension 250 | 396
adult high grade glioma 249 | 3,801
pancreatic cancer 246 | 2,398
Astrocytoma, Pilocytic 241 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 236 | 2,989
Heart disease 212 | 306
Kidney disease 211 | 430
group 3 medulloblastoma 211 | 4,104
interstitial cystitis 206 | 2,312
tuberculosis 202 | 2,010
ulcerative colitis 197 | 1,819
cystic fibrosis 196 | 1,696
Vascular disease 191 | 319
primitive neuroectodermal tumor 179 | 3,035
ductal carcinoma in situ 176 | 1,745
oligodendroglioma 176 | 2,850
Schizophrenia 175 | 1,160
Coronary artery disease 174 | 268
Kidney cancer 174 | 2,613
breast carcinoma 173 | 1,638
Atherosclerosis 172 | 291
Obesity 172 | 678
pituitary cancer 163 | 1,972
subependymal giant cell astrocytoma 163 | 2,287
Autosomal recessive predisposition 158 | 1,442
Cerebrovascular disease 156 | 238
colon cancer 154 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 151 | 1,962
Hypertensive disease 139 | 292
Liver Cirrhosis, Experimental 139 | 769
Rheumatoid arthritis 137 | 1,191
adrenocortical carcinoma 137 | 1,428
astrocytic glioma 137 | 2,597
Arthritis 135 | 290
group 4 medulloblastoma 129 | 1,855
Alzheimer's disease 124 | 658
Asthma 122 | 385
Breast Neoplasms 117 | 445
Mammary Neoplasms 116 | 425
cutaneous lupus erythematosus 116 | 1,057
acute quadriplegic myopathy 114 | 1,158
Bipolar Disorder 107 | 666
gastric carcinoma 107 | 807
primary pancreatic ductal adenocarcinoma 107 | 1,109
astrocytoma 105 | 1,146
juvenile dermatomyositis 105 | 1,187
Multiple Sclerosis 104 | 540
Prostatic Neoplasms 102 | 495
Anemia 100 | 365
Pick disease 100 | 1,894
Depressive disorder 99 | 409
Liver disease 99 | 237
Lung disease 98 | 142
Myocardial Infarction 96 | 151
dermatomyositis 94 | 966
Multiple myeloma 93 | 1,332
Heart failure 92 | 162
Hypersensitivity reaction type II disease 91 | 253
Atopic dermatitis 90 | 952
Epilepsy 87 | 792
nasopharyngeal carcinoma 86 | 1,058
Osteoporosis 84 | 363
Duchenne muscular dystrophy 80 | 601
Inflammatory bowel disease 80 | 151
Hyperglycemia 78 | 137
Melanoma 78 | 711
Seizures 78 | 596
Stomach Neoplasms 78 | 300
esophageal adenocarcinoma 77 | 737
Mental Depression 76 | 333
Neoplasm Metastasis 76 | 168
Neurodegenerative disease 76 | 414
Major Depressive Disorder 75 | 301
fibroadenoma 75 | 559
Endometriosis 74 | 540
Lung Neoplasms 74 | 232
active ulcerative colitis 73 | 764
pediatric high grade glioma 72 | 1,064
Diarrhea 71 | 253
mucosa-associated lymphoid tissue lymphoma 71 | 484
Intellectual disability 70 | 1,016

Tissue

Endocrine System 893 | 18,159
Digestive Tract 886 | 17,369
Female tissues 881 | 17,400
Skin and soft tissues 880 | 17,230
Male tissues 877 | 17,142
Liver and Pancreas 873 | 16,750
Urinary Tract 871 | 16,678
Blood and immune system 866 | 16,909
Respiratory system 854 | 16,393
Nervous System 852 | 16,725
Cardiovascular System 822 | 15,192

Target Family

Non-IDG 444 | 12,091
Enzyme 198 | 4,145
Kinase 74 | 634
Transcription Factor 73 | 1,400
Ion Channel 42 | 344
GPCR 41 | 408
Transporter 23 | 473
Epigenetic 12 | 242
Nuclear Receptor 7 | 48

Jensen-TM Tissue

Heart 914 | 914
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121