Development Level

Tbio 185 | 11,445
Tchem 43 | 1,598
Tclin 19 | 613
Tdark 17 | 6,588

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased bone mineral content 7 | 151
male infertility 7 | 123
preweaning lethality, incomple... 7 | 499
decreased lean body mass 6 | 135
female infertility 6 | 60
improved glucose tolerance 6 | 79
increased total body fat amoun... 6 | 134
abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
increased circulating alkaline... 5 | 122
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal retina morphology 4 | 71
decreased body weight 4 | 161
decreased bone mineral density 4 | 126
enlarged heart 4 | 210
increased startle reflex 4 | 112
small testis 4 | 58
abnormal coat appearance 3 | 31
abnormal heart morphology 3 | 162
abnormal kidney morphology 3 | 65
decreased spleen weight 3 | 10
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased fasted circulating g... 3 | 76
increased grip strength 3 | 41
increased lean body mass 3 | 172
increased leukocyte cell numbe... 3 | 47
limb grasping 3 | 41
abnormal male genitalia morpho... 2 | 3
abnormal seminal vesicle morph... 2 | 114
abnormal vibrissa morphology 2 | 25
cleft palate 2 | 8
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating choleste... 2 | 66
increased hemoglobin content 2 | 45
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
pale yolk sac 2 | 25
short tibia 2 | 97
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal chorioallantoic fusio... 1 | 8
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart looping 1 | 5
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal snout morphology 1 | 23
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal visceral yolk sac mor... 1 | 6
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent spleen 1 | 3
cataract 1 | 92
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased heart left ventricle... 1 | 28
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged lymph nodes 1 | 37
increased aggression 1 | 4
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
polycystic kidney 1 | 15
shortened PQ interval 1 | 7
small kidney 1 | 16
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16
thin ventricular wall 1 | 24

Disease

Carcinoma 166 | 11,493
Cancer 124 | 2,499
ovarian cancer 112 | 8,520
psoriasis 105 | 6,694
medulloblastoma, large-cell 87 | 6,241
osteosarcoma 87 | 7,950
lung cancer 79 | 4,740
glioblastoma 78 | 5,792
Infertility 74 | 188
Male infertility 74 | 206
malignant mesothelioma 69 | 3,232
atypical teratoid / rhabdoid tumor 65 | 5,112
Breast cancer 63 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,291
Kidney cancer 57 | 2,613
ependymoma 56 | 4,679
non-small cell lung cancer 55 | 2,890
group 3 medulloblastoma 51 | 4,104
invasive ductal carcinoma 51 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,989
pancreatic cancer 48 | 2,398
Astrocytoma, Pilocytic 45 | 3,081
ductal carcinoma in situ 43 | 1,745
primitive neuroectodermal tumor 43 | 3,035
oligodendroglioma 41 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
lung adenocarcinoma 40 | 2,716
breast carcinoma 39 | 1,638
adult high grade glioma 38 | 3,801
astrocytic glioma 38 | 2,597
adrenocortical carcinoma 37 | 1,428
diabetes mellitus 37 | 1,728
Breast Neoplasms 36 | 445
Schizophrenia 36 | 1,160
cystic fibrosis 36 | 1,696
pituitary cancer 36 | 1,972
Mammary Neoplasms 35 | 425
ulcerative colitis 34 | 1,819
interstitial cystitis 32 | 2,312
tuberculosis 32 | 2,010
Autosomal recessive predisposition 31 | 1,442
subependymal giant cell astrocytoma 31 | 2,287
Cryptorchidism 30 | 296
Prostatic Neoplasms 29 | 495
Osteoporosis 28 | 363
colon cancer 28 | 1,478
Polycystic ovary syndrome 26 | 360
Short stature 26 | 531
group 4 medulloblastoma 26 | 1,855
lung carcinoma 26 | 2,843
Endometriosis 25 | 540
Azoospermia 24 | 110
Premature ovarian failure 24 | 65
Carcinoma, Hepatocellular 23 | 228
Intellectual disability 23 | 1,016
Liver carcinoma 23 | 240
acute quadriplegic myopathy 23 | 1,158
Adenoma 22 | 167
Alzheimer's disease 22 | 658
Epilepsy 22 | 792
Gonadoblastoma 22 | 34
Hypogonadism 22 | 173
Pick disease 22 | 1,894
Stomach Neoplasms 22 | 300
Vascular disease 22 | 319
Kidney disease 21 | 430
Rheumatoid arthritis 21 | 1,191
juvenile dermatomyositis 21 | 1,187
Cognitive delay 20 | 608
Global developmental delay 20 | 608
Heart disease 20 | 306
Lung Neoplasms 20 | 232
Mental and motor retardation 20 | 608
Seizures 20 | 596
cutaneous lupus erythematosus 20 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pediatric high grade glioma 20 | 1,064
Melanoma 19 | 711
nasopharyngeal carcinoma 19 | 1,058
Atopic dermatitis 18 | 952
Cleft Palate 18 | 271
Obesity 18 | 678
Bipolar Disorder 17 | 666
Dull intelligence 17 | 645
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Skin cancer 17 | 469
primary pancreatic ductal adenocarcinoma 17 | 1,109
Down syndrome 16 | 499
Hypertension 16 | 396
Neurodegenerative disease 16 | 414
gastric carcinoma 16 | 807
spina bifida 16 | 1,074
Adenocarcinoma 15 | 122
Colorectal Neoplasms 15 | 243
Klinefelter's syndrome 15 | 56
Multiple myeloma 15 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510

Tissue

Endocrine System 256 | 18,159
Digestive Tract 229 | 17,369
Female tissues 228 | 17,400
Male tissues 224 | 17,142
Blood and immune system 217 | 16,909
Skin and soft tissues 217 | 17,230
Liver and Pancreas 209 | 16,750
Nervous System 203 | 16,725
Respiratory system 202 | 16,393
Urinary Tract 202 | 16,678
Cardiovascular System 174 | 15,192

Target Family

Non-IDG 144 | 12,091
Enzyme 44 | 4,145
Transcription Factor 32 | 1,400
Kinase 15 | 634
Epigenetic 9 | 242
Nuclear Receptor 6 | 48
Transporter 5 | 473
GPCR 4 | 408
TF/Epigenetic 3 | 38
Ion Channel 2 | 344

Jensen-TM Tissue

Germ cell 264 | 264
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Solute carrier family 2, facilitated glucose transporter member 8 SLC2A8 Tbio Transporter -1.54482 35.6 110
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Sal-like protein 4 SALL4 Tbio Transcription Factor -2.64737 454.3 165
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 SOHLH2 Tbio Transcription Factor -1.26578 21.4 126
HORMA domain-containing protein 1 HORMAD1 Tbio Non-IDG -1.44656 27.9 135
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
Sperm protamine P1 PRM1 Tbio Non-IDG -2.17603 144.2 30