Development Level

Tbio 170 | 11,651
Tclin 86 | 612
Tchem 76 | 1,388
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 13 | 499
abnormal behavior 9 | 298
decreased bone mineral content 7 | 151
decreased vertical activity 7 | 208
hyperactivity 7 | 148
hypoactivity 7 | 132
increased circulating sodium l... 7 | 71
decreased total body fat amoun... 6 | 207
increased circulating alkaline... 6 | 122
increased total body fat amoun... 6 | 134
prolonged ST segment 6 | 36
decreased body weight 5 | 161
decreased grip strength 5 | 116
decreased lean body mass 5 | 135
increased circulating chloride... 5 | 41
increased lean body mass 5 | 172
prolonged QT interval 5 | 38
abnormal behavioral response t... 4 | 66
abnormal bone structure 4 | 187
decreased neutrophil cell numb... 4 | 42
embryonic lethality prior to t... 4 | 278
limb grasping 4 | 41
abnormal gait 3 | 69
decreased circulating LDL chol... 3 | 38
decreased circulating alkaline... 3 | 46
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
embryonic lethality prior to o... 3 | 239
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased circulating choleste... 3 | 66
increased circulating triglyce... 3 | 42
increased fasted circulating g... 3 | 76
increased startle reflex 3 | 112
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal social-conspecific in... 2 | 3
cardiovascular system phenotyp... 2 | 36
decreased basophil cell number 2 | 16
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased circulating amylase ... 2 | 28
decreased circulating calcium ... 2 | 36
decreased circulating sodium l... 2 | 22
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased fasted circulating g... 2 | 65
decreased heart left ventricle... 2 | 28
decreased heart weight 2 | 27
decreased hemoglobin content 2 | 68
decreased mean platelet volume 2 | 25
edema 2 | 59
embryonic growth retardation 2 | 106
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating alanine ... 2 | 13
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased exploration in new e... 2 | 8
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal epididymis morphology 1 | 42
abnormal neural tube closure 1 | 46
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatine... 1 | 4
decreased circulating magnesiu... 1 | 13
decreased food intake 1 | 13
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
premature death 1 | 5

Disease

Carcinoma 233 | 11,493
Schizophrenia 185 | 1,160
glioblastoma 166 | 5,792
medulloblastoma, large-cell 157 | 6,241
psoriasis 155 | 6,694
ependymoma 145 | 4,679
atypical teratoid / rhabdoid tumor 143 | 5,112
ovarian cancer 136 | 8,520
osteosarcoma 130 | 7,950
Depressive disorder 128 | 409
Cancer 126 | 2,499
Bipolar Disorder 121 | 666
adult high grade glioma 121 | 3,801
Astrocytoma, Pilocytic 114 | 3,081
Parkinson's disease 114 | 392
oligodendroglioma 114 | 2,850
Alzheimer's disease 112 | 658
lung cancer 108 | 4,740
group 3 medulloblastoma 106 | 4,104
Mental Depression 104 | 333
primitive neuroectodermal tumor 94 | 3,035
Epilepsy 93 | 792
Toxic encephalopathy 93 | 141
Alcoholic Intoxication, Chronic 89 | 289
astrocytic glioma 89 | 2,597
malignant mesothelioma 89 | 3,232
Major Depressive Disorder 85 | 301
lung carcinoma 84 | 2,843
Breast cancer 83 | 3,578
diabetes mellitus 77 | 1,728
Mood Disorders 74 | 184
Seizures 72 | 596
Unipolar Depression 71 | 250
Hypertension 68 | 396
Obesity 68 | 678
invasive ductal carcinoma 65 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
Dementia 61 | 175
Kidney cancer 61 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 61 | 2,989
pituitary cancer 61 | 1,972
subependymal giant cell astrocytoma 61 | 2,287
Autistic Disorder 58 | 364
Cerebrovascular disease 58 | 238
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,291
Neurodegenerative disease 57 | 414
interstitial cystitis 57 | 2,312
non-small cell lung cancer 56 | 2,890
Brain disease 55 | 96
Pick disease 55 | 1,894
lung adenocarcinoma 55 | 2,716
Cocaine-Related Disorders 52 | 92
breast carcinoma 52 | 1,638
colon cancer 52 | 1,478
Neuropathy 49 | 261
cystic fibrosis 49 | 1,696
Pain agnosia 48 | 104
Heart disease 47 | 306
Intellectual disability 47 | 1,016
Autosomal recessive predisposition 46 | 1,442
Alcohol dependence 45 | 107
Attention deficit hyperactivity disorder 45 | 278
group 4 medulloblastoma 45 | 1,855
ulcerative colitis 45 | 1,819
Down syndrome 44 | 499
Kidney disease 44 | 430
pancreatic cancer 42 | 2,398
Hyperalgesia 40 | 83
Migraine 40 | 83
ductal carcinoma in situ 40 | 1,745
tuberculosis 40 | 2,010
Hypertensive disease 39 | 292
Vascular disease 39 | 319
Nerve Degeneration 38 | 121
Amyotrophic lateral sclerosis 37 | 451
Asthma 37 | 385
astrocytoma 36 | 1,146
Substance abuse 35 | 59
Endometriosis 34 | 540
Huntington's disease 34 | 76
Pain 34 | 103
Liver Cirrhosis, Experimental 33 | 769
adrenocortical carcinoma 33 | 1,428
Cognitive delay 32 | 608
Constipation 32 | 181
Global developmental delay 32 | 608
Mental and motor retardation 32 | 608
Diarrhea 31 | 253
Hyperglycemia 31 | 137
Hypotension 31 | 82
Osteoporosis 30 | 363
Prostatic Neoplasms 30 | 495
Rheumatoid arthritis 30 | 1,191
Arthritis 29 | 290
Breast Neoplasms 29 | 445
Mammary Neoplasms 29 | 425
Adenoma 28 | 167
Melanoma 28 | 711
Multiple Sclerosis 28 | 540
Status Epilepticus 28 | 98

Tissue

Endocrine System 324 | 18,159
Nervous System 311 | 16,725
Female tissues 306 | 17,400
Skin and soft tissues 306 | 17,230
Digestive Tract 305 | 17,369
Male tissues 288 | 17,142
Liver and Pancreas 286 | 16,750
Blood and immune system 284 | 16,909
Urinary Tract 279 | 16,678
Respiratory system 268 | 16,393
Cardiovascular System 235 | 15,192

Target Family

Non-IDG 140 | 12,091
Enzyme 48 | 4,145
GPCR 44 | 408
Ion Channel 35 | 344
Transcription Factor 26 | 1,400
Kinase 18 | 634
Transporter 16 | 473
Nuclear Receptor 6 | 48
Epigenetic 1 | 242

Jensen-TM Tissue

Ganglion 334 | 334
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610