Development Level

Tbio 152 | 10,625
Tchem 89 | 1,890
Tclin 79 | 602
Tdark 2 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 9 | 226
decreased lean body mass 9 | 195
preweaning lethality, incomple... 9 | 260
decreased bone mineral content 7 | 157
decreased grip strength 7 | 123
increased circulating alkaline... 6 | 119
abnormal bone structure 5 | 131
decreased body weight 5 | 174
decreased total body fat amoun... 5 | 186
hyperactivity 5 | 108
hypoactivity 5 | 89
increased circulating sodium l... 5 | 71
increased lean body mass 5 | 107
embryonic lethality prior to t... 4 | 187
impaired glucose tolerance 4 | 52
increased circulating HDL chol... 4 | 63
increased circulating chloride... 4 | 43
male infertility 4 | 62
abnormal behavioral response t... 3 | 52
abnormal epididymis morphology 3 | 31
abnormal gait 3 | 51
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased heart weight 3 | 44
decreased prepulse inhibition 3 | 52
decreased vertical activity 3 | 22
enlarged epididymis 3 | 27
increased blood urea nitrogen ... 3 | 44
increased circulating choleste... 3 | 53
increased startle reflex 3 | 38
limb grasping 3 | 35
straub tail 3 | 26
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
abnormal social/conspecific in... 2 | 3
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 35
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating serum al... 2 | 79
decreased circulating sodium l... 2 | 18
decreased circulating triglyce... 2 | 83
decreased exploration in new e... 2 | 9
decreased fasted circulating g... 2 | 49
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
immune system phenotype 2 | 17
improved glucose tolerance 2 | 56
increased body weight 2 | 42
increased circulating alanine ... 2 | 11
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased mean corpuscular vol... 2 | 91
persistence of hyaloid vascula... 2 | 22
short tibia 2 | 82
tremors 2 | 34
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased effector memory CD8-... 1 | 24
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
decreased red blood cell distr... 1 | 11
decreased total retina thickne... 1 | 20
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased blood uric acid leve... 1 | 5
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
premature death 1 | 5
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

glioblastoma 150 | 5,572
psoriasis 149 | 6,685
medulloblastoma, large-cell 147 | 6,234
osteosarcoma 129 | 7,933
ovarian cancer 126 | 8,484
Cancer 120 | 2,346
Schizophrenia 111 | 501
Parkinson's disease 110 | 364
oligodendroglioma 109 | 2,849
pilocytic astrocytoma 108 | 3,086
atypical teratoid / rhabdoid tumor 106 | 4,369
Alzheimer's disease 104 | 644
primitive neuroectodermal tumor 93 | 3,031
lung cancer 91 | 4,466
Toxic encephalopathy 87 | 131
pediatric high grade glioma 85 | 2,712
malignant mesothelioma 83 | 3,162
lung carcinoma 78 | 2,844
Epilepsy 76 | 346
diabetes mellitus 76 | 1,663
Obesity 66 | 616
astrocytic glioma 64 | 2,241
ependymoma 64 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 62 | 2,956
invasive ductal carcinoma 61 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,988
subependymal giant cell astrocytoma 58 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,289
pituitary cancer 57 | 1,972
Dementia 56 | 129
astrocytoma 56 | 1,493
Breast cancer 55 | 3,094
Carcinoma 55 | 2,147
Neurodegenerative disease 55 | 383
Cerebrovascular disease 54 | 231
Pick disease 54 | 1,893
interstitial cystitis 54 | 2,299
Bipolar Disorder 53 | 266
adult high grade glioma 53 | 2,148
posterior fossa group A ependymoma 53 | 1,511
Autistic Disorder 52 | 320
lung adenocarcinoma 52 | 2,713
Cocaine-Related Disorders 51 | 88
group 4 medulloblastoma 51 | 1,875
Brain disease 49 | 83
Hypertension 49 | 287
Pain agnosia 48 | 99
colon cancer 48 | 1,475
non-small cell lung cancer 48 | 2,798
breast carcinoma 47 | 1,614
cystic fibrosis 47 | 1,665
ulcerative colitis 47 | 2,087
Alcohol dependence 44 | 107
Seizures 44 | 95
sonic hedgehog group medulloblastoma 43 | 1,482
Down syndrome 42 | 548
Heart disease 42 | 279
Kidney disease 42 | 396
atypical teratoid/rhabdoid tumor 41 | 1,095
medulloblastoma 40 | 1,524
Major Depressive Disorder 39 | 106
Migraine 39 | 79
Neuropathy 39 | 210
Vascular disease 37 | 281
ductal carcinoma in situ 37 | 1,745
pancreatic cancer 37 | 2,300
Attention deficit hyperactivity disorder 36 | 156
group 3 medulloblastoma 36 | 2,254
posterior fossa group B ependymoma 35 | 1,530
Amyotrophic Lateral Sclerosis 33 | 431
Asthma 33 | 349
Endometriosis 33 | 535
Hyperalgesia 33 | 71
Nerve Degeneration 33 | 73
Pain 33 | 70
adrenocortical carcinoma 33 | 1,427
Hypertensive disease 32 | 193
tuberculosis 32 | 1,557
Huntington's disease 31 | 72
Diarrhea 30 | 155
Hypotension 30 | 53
Intellectual disability 30 | 573
Substance abuse 30 | 55
Adenoma 28 | 165
Mammary Neoplasms 28 | 410
Prostatic Neoplasms 28 | 471
Rheumatoid Arthritis 28 | 1,160
Hyperglycemia 27 | 120
Parkinson Disease 27 | 102
Substance Withdrawal Syndrome 27 | 52
Brain Ischemia 26 | 87
Arthritis 25 | 248
Status Epilepticus 25 | 85
Inflammation 24 | 109
Multiple Sclerosis 24 | 498
Osteoporosis 24 | 257
aldosterone-producing adenoma 24 | 664
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Amphetamine-Related Disorders 23 | 74
Atopic dermatitis 23 | 944

Tissue

Endocrine System 321 | 18,512
Female tissues 321 | 18,647
Nervous System 320 | 18,561
Digestive Tract 319 | 18,473
Urinary Tract 317 | 18,444
Skin and soft tissues 312 | 18,115
Liver and Pancreas 310 | 18,136
Cardiovascular System 309 | 17,958
Blood and immune system 305 | 17,995
Male tissues 302 | 17,969
Respiratory system 298 | 17,484

Target Family

Non-IDG 135 | 11,971
Enzyme 47 | 4,146
GPCR 44 | 406
Ion Channel 31 | 341
Transcription Factor 25 | 1,400
Kinase 17 | 634
Transporter 16 | 473
Nuclear Receptor 6 | 48
Epigenetic 1 | 242

Jensen-TM Tissue

Ganglion 322 | 322
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Properdin CFP Tbio Non-IDG -3.16935 1491.5 297
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95